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The Bench · annual readout · updated July 2026

The cheapest tirzepatide over twelve months, not over one.

We multiplied every disclosed monthly tirzepatide rate on the bench out to a year and sorted on that — ascending, nothing pinned. The spread between the cheapest and the dearest year on this board is $3,468.

Read this before the board

Almost everything below is compounded tirzepatide — a medication prepared by a compounding pharmacy that is not an FDA-approved drug. The FDA-approved brand tirzepatide is Zepbound (and Mounjaro for type 2 diabetes), both from Eli Lilly. They are not the same regulatory product, and this page does not blur the two. If you specifically want the brand and what it actually costs, start with the Zepbound cost page instead — this board is the compounded, twelve-month comparison.

Annual readout · tirzepatide

25 priced · sorted by 12-month cost

Ordered by twelve-month compounded-tirzepatide cost, ascending — not by the Cost-Efficiency Index, and not with partners floated up. For a single flat monthly rate, ×12 preserves the same order a monthly-only list would show; what it adds is everything below the board.

  1. 01

    Primary Clinic (Direct GLP)

    WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA · Index 77 C · Tirz $110/mo · Sema $780/yr

    $1,320 / 12 mo

  2. 02

    Trimi Health

    All 50 states · Index 85 B · Tirz $125/mo · Sema $1,188/yr

    $1,500 / 12 mo

  3. 03

    Found

    All 50 states · Index 88 B+ · Tirz $129/mo · Sema $1,548/yr

    $1,548 / 12 mo

  4. 04

    bmiMD

    All 50 states · Index 84 B · Tirz $139/mo · Sema $1,188/yr

    $1,668 / 12 mo

  5. 05

    NewSelf

    All 50 states · Index 87 B+ · Tirz $144/mo · Sema $1,200/yr

    $1,728 / 12 mo

  6. 06

    Alan Meds

    All 50 states · Index 84 B · Tirz $145/mo · Sema $1,188/yr

    $1,740 / 12 mo

  7. 07

    Vitara RX

    All 50 states · Index 87 B+ · Tirz $149/mo · Sema $1,188/yr

    $1,788 / 12 mo

  8. 08

    Gimme Care

    All 50 states · Index 87 B+ · Tirz $163/mo · Sema $1,560/yr

    $1,956 / 12 mo

  9. 09

    Ondra Health

    All 50 states · Index 90 A− · Tirz $166/mo · Sema $1,116/yr

    $1,992 / 12 mo

  10. 10

    Live Vital

    All 50 states · Index 82 B− · Tirz $183/mo · Sema $1,188/yr

    $2,196 / 12 mo

  11. 11

    Precision Telemed

    All 50 states · Index 87 B+ · Tirz $199/mo · Sema $1,788/yr

    $2,388 / 12 mo

  12. 12

    Sprout Health

    Most states · Index 85 B · Tirz $199/mo · Sema $1,788/yr

    $2,388 / 12 mo

  13. 13

    Curex

    All 50 states · Index 85 B · Tirz $199/mo · Sema $2,388/yr

    $2,388 / 12 mo

  14. 14

    Piper

    All 50 states · Index 82 B− · Tirz $199/mo · Sema $1,620/yr

    $2,388 / 12 mo

  15. 15

    Kongo

    All 50 states · Index 86 B · Tirz $229/mo · Sema $1,428/yr

    $2,748 / 12 mo

  16. 16

    Shed (tryshed.com)

    Not disclosed · Index 85 B · Tirz $239/mo · Sema $1,908/yr

    $2,868 / 12 mo

  17. 17

    Effecty

    All 50 states · Index 86 B · Tirz $240/mo · Sema $1,920/yr

    $2,880 / 12 mo

  18. 18

    PepHaūs

    All 50 states · Index 85 B · Tirz $246/mo · Sema $1,824/yr

    $2,952 / 12 mo

  19. 19

    NP2GO

    AK, AZ, AR, CA, CO, CT, DE, DC, FL, HI, ID, IL, IA, KS, KY, ME, MD, MA, MI, MN, MT, NE, NV, NH, NJ, NM, NY, ND, OK, OR, PA, RI, SD, TX, UT, VT, VA, WA, WV, WY · Index 79 C · Tirz $250/mo · Sema $1,800/yr

    $3,000 / 12 mo

  20. 20

    ShedRx

    Not disclosed · Index 87 B+ · Tirz $299/mo · Sema $2,388/yr

    $3,588 / 12 mo

  21. 21

    Invigor Medical

    Not disclosed · Index 88 B+ · Tirz $339/mo · Sema $2,388/yr

    $4,068 / 12 mo

  22. 22

    CoreAge Rx

    All 50 states · Index 94 A · Tirz $349/mo · Sema $1,788/yr

    $4,188 / 12 mo

  23. 23

    Eden

    All 50 states · Index 86 B · Tirz $349/mo · Sema $2,868/yr

    $4,188 / 12 mo

  24. 24

    Henry Meds

    Multi-state · Index 81 B− · Tirz $349/mo · Sema $2,988/yr

    $4,188 / 12 mo

  25. 25

    Breeze Meds

    All 50 states · Index 86 B · Tirz $399/mo · Sema $2,388/yr

    $4,788 / 12 mo

  26. 26

    Sesame Care

    Nationwide · Index 86 B · Tirz Brand (Zepbound) · Sema not disclosed

    Not disclosed — sorted last

  27. 27

    AgelessRx

    Not disclosed · Index 85 B · Tirz Not disclosed · Sema $1,668/yr

    Not disclosed — sorted last

  28. 28

    Ro

    Multi-state · Index 84 B · Tirz Not disclosed · Sema not disclosed

    Not disclosed — sorted last

  29. 29

    Hims & Hers

    All 50 states · Index 83 B · Tirz Not disclosed · Sema $2,388/yr

    Not disclosed — sorted last

  30. 30

    Care Bare Rx

    Multi-state · Index 80 B− · Tirz Not disclosed · Sema not disclosed

    Not disclosed — sorted last

Method · Twelve-month figures are the disclosed monthly tirzepatide rate × 12 — the sticker taken at its word, not a quote. Nothing is estimated: dose escalation, first-month promotions, consult and lab fees and separate memberships are not in the number, so read every row as a floor. This board is ordered purely by annual cost; on our other ranking surfaces affiliate partners carry a capped 3-point edge in listing ORDER only, never in the score, and we disclose that rather than deny it. See the disclosure and methodology.

$3,468 separates the cheapest tirzepatide year from the dearest

Primary Clinic (Direct GLP) anchors the bottom of the board at $110/mo — about $1,320 across a year. At the other end, Breeze Meds runs $4,788 for the same twelve months of the same molecule. That gap does not come from the drug — it comes from the program wrapped around it.

Primary Clinic (Direct GLP) serves WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA — a price you cannot legally buy in your state is not a price. Among providers publishing an all-50-state footprint the cheapest tirzepatide year is Trimi Health at $1,500, and that is the number most readers should actually compare against.

What monthly-only lists don't show: the sema-to-tirz premium

For a flat monthly rate, multiplying by 12 keeps the same order a monthly list already shows — we won't pretend otherwise. Where this board earns its keep is the number no sticker-price list computes: at the 25 providers on our roster that disclose both molecules, tirzepatide costs more than semaglutide over a year at every one of them except where the two are priced identically. The premium ranges from $0 a year (as low as Found) to $2,400 a year (at Breeze Meds), averaging about $921. 2 providers on that list — Found and Curex — charge the same price for both molecules.

ProviderSema / yrTirz / yrAnnual premium
Found$1,548$1,548Same price
Curex$2,388$2,388Same price
Trimi Health$1,188$1,500+$312
Gimme Care$1,560$1,956+$396
bmiMD$1,188$1,668+$480
NewSelf$1,200$1,728+$528
Primary Clinic (Direct GLP)$780$1,320+$540
Alan Meds$1,188$1,740+$552
Sprout Health$1,788$2,388+$600
Vitara RX$1,188$1,788+$600
Precision Telemed$1,788$2,388+$600
Piper$1,620$2,388+$768
Ondra Health$1,116$1,992+$876
Shed (tryshed.com)$1,908$2,868+$960
Effecty$1,920$2,880+$960
Live Vital$1,188$2,196+$1,008
PepHaūs$1,824$2,952+$1,128
ShedRx$2,388$3,588+$1,200
Henry Meds$2,988$4,188+$1,200
NP2GO$1,800$3,000+$1,200
Eden$2,868$4,188+$1,320
Kongo$1,428$2,748+$1,320
Invigor Medical$2,388$4,068+$1,680
CoreAge Rx$1,788$4,188+$2,400
Breeze Meds$2,388$4,788+$2,400

What the annual figure leaves out

Every number above is the disclosed monthly rate multiplied by twelve — we invent no cost the roster does not record. That multiplier also does not tell you where you can legally buy the price. Of the 25 providers on this priced board, 7 do not publish an all-50-state footprint:

  • Primary Clinic (Direct GLP)WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA
  • Sprout HealthMost states
  • Shed (tryshed.com)Not disclosed
  • NP2GOAK, AZ, AR, CA, CO, CT, DE, DC, FL, HI, ID, IL, IA, KS, KY, ME, MD, MA, MI, MN, MT, NE, NV, NH, NJ, NM, NY, ND, OK, OR, PA, RI, SD, TX, UT, VT, VA, WA, WV, WY
  • ShedRxNot disclosed
  • Invigor MedicalNot disclosed
  • Henry MedsMulti-state

Dose escalation, a promotional first month that resets, and consult, lab or membership fees are also not in the number — the method is the same one behind the true monthly cost of GLP-1, and the cost calculators will run your own numbers.

Cheapest tirzepatide, answered

What is the cheapest tirzepatide provider over a full year?
At its disclosed monthly rate, Primary Clinic (Direct GLP) carries the lowest twelve-month tirzepatide cost we track — $110/mo works out to about $1,320 a year. It serves WA, NM, AZ, UT, FL, DC, KS, OK, VA, GA, which is the catch. Among providers publishing an all-50-state footprint, the lowest twelve-month figure is Trimi Health at about $1,500.
Is the cheapest tirzepatide compounded or brand-name Zepbound?
Compounded, on every row of this board. Zepbound is Eli Lilly's FDA-approved brand tirzepatide, and it is not what most of this roster sells — compounded tirzepatide is a different, non-FDA-approved product from a compounding pharmacy. If you specifically want the brand, start at /best/zepbound-cost rather than here.
How much more does tirzepatide cost than semaglutide at the same provider?
Across the 25 providers on our roster that disclose both molecules, the annual premium for tirzepatide over semaglutide ranges from $0 to $2,400 a year, averaging about $921. 2 providers on that list price both molecules identically.
Does multiplying the monthly rate by 12 change the ranking versus a monthly-only list?
No — for a single flat monthly rate, multiplying by 12 preserves the same order a monthly list would show. What a monthly-only list does not show is the dollar spread over a full year, the sema-to-tirz premium at the same provider, and which of the cheapest rows are actually available nationwide. That is what the rest of this page adds.
What does the twelve-month tirzepatide figure leave out?
It is the disclosed monthly tirzepatide rate multiplied by twelve — the sticker taken at its word, nothing added and nothing estimated. It does not model dose escalation into a higher price tier, a promotional first month that resets, one-time consultation or lab fees, or a membership charged alongside the medication. Every one of those pushes the real figure up, never down.

The other boards

Related reading: compounded vs brand-name GLP-1 cost, is compounded medication legit and safe, semaglutide vs tirzepatide value, or line two finalists up side by side.

Prices are each provider's public disclosures at last check and move fast — confirm before you buy. Compounded medications are not FDA-approved. Not medical advice; see our medical disclaimer.