The Bench
GLP-1 cost calculators: semaglutide & tirzepatide
Three auditable models built on published provider prices. Run the numbers on what a program really costs before you commit — then check the Cost-Efficiency Index to see which price is actually good value.
The short answer
Across the providers we track with a published compounded semaglutide price, monthly cash cost runs $49–$399/mo, with a median near $179/mo. The lowest disclosed sticker is $49/mo at NextMeds. Our partner CoreAge Rx models to $99/mo = $1,188/yr on a flat, all-50 price with no teaser step-up — the lowest cost over a year isn't always the lowest sticker. The calculators below let you model any provider yourself.
Semaglutide cost-per-month, at a glance
The ten lowest disclosed compounded-semaglutide monthly prices among the programs we track, with the modeled annual cost (the price × the charges in a year: 13, not 12, for a plan billed every four weeks, plus any membership the company requires and publishes at a fixed amount). Figures reflect each provider's published price at last review — illustrative, not a quote.
| Provider | Semaglutide / mo | Modeled / yr | Index |
|---|---|---|---|
| NextMeds | $49 | $588 | 87 |
| Collective | $59 | $907includes $199/yr membership | 65 |
| Ivy Rx | $77 | $924 | 76 |
| Tryozi | $79 | $948 | 88 |
| Lean Meds | $79 | $948 | 84 |
| NuuVim | $79 | $948 | 81 |
| Vivanta Care | $79 | $948 | 80 |
| Embody | $79 | $948 | 77 |
| Good Girl Rx | $79 | $948 | 66 |
| RxPepsDirect | $79 | $948 | 60 |
Want the buyer's shortlist instead of the raw table? See the cheapest GLP-1 providers worth using.
GLP-1 monthly cost calculator — semaglutide & tirzepatide
Monthly Cost Calculator
Live modelModeled / month
$99
Modeled / year
$1,188
As CoreAge Rx publishes it: $99/mo
Lowest modeled monthly total for semaglutide among the programs we track: NextMeds at $49/mo — but check the full Cost-Efficiency Index before you decide on price alone.
Monthly total = modeled annual cost divided by 12, including required fixed fees and billing cadence. Excludes shipping, labs, and consult fees where not bundled. Prices change — confirm on the provider's site. Not medical advice.
Compounded vs. brand savings calculator
Compounded-vs-Brand Savings
EstimatorSave / mo
$1,250
Save / yr
$15,000
Cheaper by
93%
As CoreAge Rx publishes it: $99/mo
Modeled monthly cost is annual cost divided by 12, including required fixed fees and billing cadence. Baseline uses approximate US manufacturer list (cash) prices — $1,349/mo Wegovy, $1,059/mo Zepbound — which change over time and may be lower with insurance or manufacturer savings programs. Compounded GLP-1s are not FDA-approved finished drugs. Illustrative only; confirm current prices. Not medical advice.
GLP-1 cost-per-month table — every provider
Open the full sortable table
Browse the providers we track, toggle semaglutide or tirzepatide, sorted by disclosed monthly price with the Cost-Efficiency Index alongside each row.
GLP-1 cost questions, answered
- How much does semaglutide cost per month?
- Across the providers we track with a published compounded semaglutide price, the monthly cash cost runs from $49 to $399, with a median of about $179/mo. The lowest disclosed sticker is $49/mo at NextMeds. Use the Monthly Cost Calculator above to model any provider's monthly and annual cost.
- What is the cheapest GLP-1 provider?
- NextMeds lists the lowest disclosed monthly semaglutide price at $49/mo. The cheapest sticker is not always the lowest cost over a year — our partner CoreAge Rx, for example, models to $99/mo ($1,188/yr) because its flat, all-50 pricing has no teaser step-up. The Cost-per-Month table lets you sort every provider and cross-check the Cost-Efficiency Index.
- How much can I save with compounded semaglutide vs. brand-name Wegovy?
- Brand-name Wegovy lists near $1,349/mo cash. A compounded semaglutide program at the median $179/mo models to roughly $1,170/mo — about $14,040/yr — in savings before insurance or manufacturer programs. The Savings Estimator above shows the figure for any provider you pick. Compounded GLP-1s are not FDA-approved finished drugs.
- Are these GLP-1 cost calculators free?
- Yes. Every calculator here is free, requires no account, and runs entirely in your browser. The math is modeled from each provider's published price at last review and is illustrative, not a quote — always confirm the current price on the provider's own site.
Every figure is modeled from each provider's published price at last review and is illustrative, not a quote. Compounded GLP-1 medications are not FDA-approved finished drug products. Talk to a licensed clinician before starting any weight-management medication. See our methodology and disclosure.