Nucific review
Nucific -- historically a Bio X4 supplement brand -- now runs a GLP-1 telehealth funnel with clinical care delivered through OpenLoop Health's licensed-provider network, prescribing real compounded semaglutide and tirzepatide.
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Yes
Pricing verified August 2026
The Index scorecard
Nucific scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Uses OpenLoop Health, a known legitimate telehealth clinical backend, for prescribing
- Offers real compounded semaglutide and tirzepatide, not just a supplement
- Established consumer brand with existing customer base from its supplement business
The tradeoffs
- No price for the prescription GLP-1 program could be found or verified
- Same brand simultaneously sells an unrelated OTC 'GLP-1 Balance' supplement, high risk of shopper confusion
- No medical director named
- No specific compounding pharmacy, states-served list, or LegitScript certification found
The bottom line
Best for: Cost-first shoppers who want not currently recommendable without verified pricing; flag for re-check before publishing a review. Nucific -- historically a Bio X4 supplement brand -- now runs a GLP-1 telehealth funnel with clinical care delivered through OpenLoop Health's licensed-provider network, prescribing real compounded semaglutide and tirzepatide.
Ranked #521 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Nucific.
- #522Teladoc Health— Teladoc Health is the large, publicly traded telehealth company; its GLP-1 program is only accessible through an employer- or insurance-sponsored plan.41/100
- #523Thriving Again— Thriving Again is a men's health telehealth platform bundling TRT, peptides, hair restoration, and GLP-1 weight loss under one membership model, claiming coverage in all 50 states.41/100
- #524Ways2Well— Ways2Well is a concierge functional-medicine membership (founded by Brigham Buhler) built around biannual biomarker panels and personalized protocols that CAN include semaglutide/tirzepatide, peptides.41/100
- #525Cabana— Cabana is a concierge wellness brand offering compounded GLP-1 semaglutide and tirzepatide (injections and a semaglutide tablet) alongside NAD+ energy products, advertised from $249/month.40/100
- #526LevelUp Rx— LevelUp Rx is a broad multi-vertical telehealth pharmacy that lists GLP-1/weight-loss medications among several unrelated categories (hair loss, beauty, sexual health, longevity) but discloses zero actual pricing anywhere on its public site.40/100
- #527Wellspring Longevity Clinic— Wellspring Longevity Clinic is a longevity-focused telehealth service offering compounded GLP-1 (semaglutide) and dual GLP-1/GIP (tirzepatide) for weight management, plus NAD+, peptide therapy.40/100
The 18 programs nearest this one
- #528 LovelyMeds39
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- #531 Bodyshop Wellness39
- #532 Vital Harmony Rx39
- #533 Immortals38
- #534 Modern Age38
- #535 myRocky38
- #536 RxSaludable38
- #537 California Trim Clinic37
- #538 Believe Health37
- #539 Thryve22
- #1 CoreAge Rx94
- #2 Found88
- #3 Ondra Health90
- #4 ShedRx (Shed)87
- #5 Strut Health87
- #6 Breeze Meds86
Pricing, states and verification reflect Nucific's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Nucific's site. Not medical advice; see our disclosure.