What is the cheapest semaglutide provider over a full year?

At its disclosed rate, plus any required published fee, Collective carries the lowest twelve-month semaglutide cost we track — $59/mo for the medication, plus a required $199/year membership billed separately works out to about $907 a year. It serves 44 states (not AL, CA, LA, MA, MS or WA), which is the catch. Among providers publishing an all-50-state footprint, the lowest twelve-month figure is Tryozi at about $948.

Is cheap compounded semaglutide the same as Wegovy or Ozempic?

No. Wegovy and Ozempic are Novo Nordisk's FDA-approved brand semaglutide — Wegovy for chronic weight management, Ozempic for type 2 diabetes, both reviewed by the FDA for safety, effectiveness and quality. Wegovy's approximate US cash list price is around $1,349/mo. Compounded semaglutide, which is almost everything here, is a different product prepared by a compounding pharmacy — same active ingredient in most cases, but not FDA-approved and not FDA-reviewed as a finished drug.

How much less does semaglutide cost than tirzepatide at the same provider?

Across the providers we track that disclose both molecules, choosing semaglutide over tirzepatide saves $-3,600 to $4,596 a year, averaging about $893. 19 providers on that list price both molecules identically, so the saving there is zero.

Does pricing a full year change which provider is cheapest?

Sometimes. A plan billed monthly is twelve charges a year, so it keeps the order a monthly list would show; a plan billed every four weeks is thirteen charges, so its year costs one charge more than its sticker suggests. What can also move a row on the page you're looking at is placement: partners are surfaced first, as they are on every ranking on this site (see our disclosure), and every row is still ordered strictly by twelve-month cost within its group. The dollar figure next to each provider is never adjusted either way.

What does the twelve-month semaglutide figure leave out?

It is the disclosed semaglutide rate times the charges in a year (13, not 12, for a plan billed every four weeks), plus any membership or care fee the company requires and publishes at a fixed monthly or yearly amount, such as a $199 annual membership. Nothing is estimated. It does not model dose escalation into a higher price tier, a promotional first month that resets, one-time consultation or lab fees, optional add-ons, or a fee the company does not publish. Every one of those pushes the real figure up, never down.

Annual price comparison · updated November 2026

The cheapest semaglutide online, over twelve months, not one.

Compare compounded semaglutide programs over a full year, including required published fees. Compounded drugs are not FDA-approved. Four-week plans count as 13 charges. Partners appear first; providers are ordered by annual cost within each group.

Listed firstPartner

Collective

Index 65 C · 44 states (not AL, CA, LA, MA, MS or WA)

$907semaglutide / yr (includes $199/yr membership)

Check price Review

Read this before the ranking

Almost everything below is compounded semaglutide — a medication prepared by a compounding pharmacy that is not an FDA-approved drug. The FDA-approved brand semaglutide is Wegovy (for chronic weight management) and Ozempic (the same molecule, approved for type 2 diabetes), both from Novo Nordisk. Wegovy's approximate US cash list price is around $1,349/mo. They are not the same regulatory product as a compounded copy, and this page does not blur the two — read the compounded-vs-brand cost breakdown for the full comparison, or is compounded semaglutide legit and safe before you buy. This ranking is the compounded, twelve-month comparison.

Compare annual semaglutide costs

Priced programs · sorted by 12-month cost

Partners appear first; providers are ordered by annual cost within each group. Four-week plans count as 13 charges. See our disclosure.

#Provider & coverage12-month sema costDetails

01
Collective
44 states (not AL, CA, LA, MA, MS or WA) · Index 65 C
Price terms: $59/mo for the medication, plus a required $199/year membership billed separately
Price & billing details
Semaglutide: $59/mo for the medication, plus a required $199/year membership billed separately
$907 / yr (includes $199/yr membership)
Check price Read review
02
Embody
All 50 states · Index 77 C
Price terms: sale price, compounded
Price & billing details
Semaglutide: $79/mo (sale price, compounded)
$948 / yr
Check price Read review
03
CoreAge Rx
All 50 states · Index 94 A
Price & billing details
Semaglutide: $99/mo
$1,188 / yr
Check price Read review
04
Eden
All 50 states · Index 94 A
Price terms: all doses, compounded
Price & billing details
Semaglutide: $99/mo (all doses, compounded)
$1,188 / yr
Check price Read review
05
Strut Health
49 states (not Arkansas) · Index 87 B+
Price & billing details
Semaglutide: From $99/mo lozenge, $129/mo injection (auto-refill)
$1,188 / yr
Check price Read review
06
Lttl
Coverage not published · Index 61 C
Price terms: $99 per 4 weeks
Price & billing details
Semaglutide: $99 per 4 weeks (compounded, auto-refill)
$1,287 / yr (13 charges)
Check price Read review
07
Belle Health
Confirm state eligibility before enrolling · Index 71 C
Price & billing details
Semaglutide: From $109/mo (compounded; confirm your plan at checkout)
$1,308 / yr
Check price Read review
08
Peter MD
Varies by treatment — semaglutide not in AL, AK, HI or ID, tirzepatide not in AL or ID; additional reported restrictions need confirmation · Index 72 C
Price terms: $149/mo first-time
Price & billing details
Semaglutide: $149/mo first-time (Level 1), $139/mo returning (Level 2)
$1,788 / yr
Check price Read review
09
bmiMD
All 50 states · Index 83 B
Price terms: $119/mo on a prepaid 12-month plan
Price & billing details
Semaglutide: $159/mo month to month ($119/mo on a prepaid 12-month plan)
$1,908 / yr
Check price Read review
10
Sprout Health
44 states (not AL, AR, CA, LA, MS or ND) · Index 80 B−
Price terms: $149 per 4 weeks; $99/mo on a prepaid 12-month plan
Price & billing details
Semaglutide: $149 per 4 weeks ($99/mo on a prepaid 12-month plan)
$1,937 / yr (13 charges)
Check price Read review
11
Bodybuilding Health+
50 states claimed, no list published · Index 74 C
Price & billing details
Semaglutide: $179/mo month-to-month; $159.33 on three months, $158 on six and $141.50 on twelve
$2,148 / yr
Check price Read review
12
HealthRX
All 50 states · Index 74 C
Price terms: all doses, compounded
Price & billing details
Semaglutide: $190/mo (all doses, compounded)
$2,280 / yr
Check price Read review
13
ShedRx (Shed)
All 50 states · Index 87 B+
Price terms: $159 on a 12-month plan
Price & billing details
Semaglutide: $199/mo ($159 on a 12-month plan)
$2,388 / yr
Check price Read review
14
Enhance MD
40 states + DC · Index 76 C
Price terms: first month $112
Price & billing details
Semaglutide: $212/mo (first month $112)
$2,544 / yr
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15
Found
All 50 states · Index 92 A−
Price terms: insurance-linked
Price & billing details
Semaglutide: $199/mo (insurance-linked)
$2,587 / yr (13 charges)
Check price Read review
16
Luvo Health
50 states claimed, no list published · Index 66 C
Price terms: $209 per 4 weeks
Price & billing details
Semaglutide: $209 per 4 weeks (injection, compounded)
$2,717 / yr (13 charges)
Check price Read review
17
RxSpan MD
All 50 states · Index 83 B
Price & billing details
Semaglutide: $249/mo month-to-month for the injection; $219 on three months, $199 on six and $194 on twelve
$2,988 / yr
Check price Read review
18
SkinnyRx
Most states · Index 74 C
Price terms: $249/mo month to month after a $99 first month; $199/mo on a 12-month plan
Price & billing details
Semaglutide: $249/mo month to month after a $99 first month ($199/mo on a 12-month plan)
$2,988 / yr
Check price Read review
19
Direct Meds
Not disclosed · Index 71 C
Price terms: sublingual, 90-day supply billed monthly
Price & billing details
Semaglutide: $249/mo (sublingual, 90-day supply billed monthly)
$2,988 / yr
Check price Read review
20
MyDrHank
Not published; program excludes KS, LA, MS, NM, ND, WV · Index 65 C
Price terms: yearly prepay: $171 / $178
Price & billing details
Semaglutide: $249/mo oral, $259/mo injectable (yearly prepay: $171 / $178)
$2,988 / yr
Check price Read review
21
Oak
45 states (list not published) · Index 77 C
Price terms: same price at every dose; $200/mo on a 3-month supply paid upfront
Price & billing details
Semaglutide: $250/mo (same price at every dose; $200/mo on a 3-month supply paid upfront)
$3,000 / yr
Check price Read review
22
Willow
35 states + Puerto Rico · Index 68 C
Price & billing details
Semaglutide: $299/mo (compounded, month to month)
$3,588 / yr
Check price Read review
23
MEDGm
All 50 states · Index 67 C
Price terms: the advertised $179 is the first month only, after an automatically applied coupon
Price & billing details
Semaglutide: $299/mo month-to-month (the advertised $179 is the first month only, after an automatically applied coupon)
$3,588 / yr
Check price Read review
24
Wellorithm
All 50 states and D.C. · Index 72 C
Price terms: fine print ties the price to a 3-month plan paid upfront
Price & billing details
Semaglutide: $899/mo (brand Wegovy; fine print ties the price to a 3-month plan paid upfront)
$10,788 / yr
Check price Read review
25
Sesame Care
Nationwide · Index 86 B
Price terms: that rate needs a 12-month commitment
Price & billing details
Semaglutide: $149/mo medication + $59/mo care subscription (that rate needs a 12-month commitment)
Not disclosed — sorted last
Check price Read review
26
Gala Health
50 states claimed, no list published · Index 71 C
Price & billing details
Semaglutide: Compounded from $129/mo (plan length not stated); brand Ozempic $1,299/mo
Not disclosed — sorted last
Check price Read review
27
WellMedr
50 states claimed, no list published · Index 54 C
Price terms: Not disclosed — sale price only, no standing rate
Price & billing details
Semaglutide: Not disclosed — sale price only, no standing rate
Not disclosed — sorted last
Check price Read review
28
EverPrime
Varies by treatment and state; confirmed during intake · Index 50 C
Price terms: optional membership pricing
Price & billing details
Semaglutide: $249 standard one-month plan; optional membership pricing
Not disclosed — sorted last
Check price Read review
29
YourEra
Coverage not published · Index 43 C
Price terms: Not disclosed — advertised from $79/mo with a new-patient coupon
Price & billing details
Semaglutide: Not disclosed — advertised from $79/mo with a new-patient coupon; the standing monthly rate shows only after you enter an email
Not disclosed — sorted last
Check price Read review
30
HumeCare+
Coverage not published · Index 42 C
Price terms: $199/mo on a 3-month plan with a welcome credit applied; medication and dose not stated; plus a separate fee at enrollment and every refill, never published
Price & billing details
Semaglutide: $199/mo on a 3-month plan with a welcome credit applied (medication and dose not stated; plus a separate fee at enrollment and every refill, never published; compounded)
Not disclosed — sorted last
Check price Read review
31
Ivy Rx
Not published; confirm eligibility · Index 76 C
Price & billing details
Semaglutide: $77/mo from (standard shared GLP-1 injection headline, compounded; confirm selected plan)
$924 / yr
Check price Read review
32
Tryozi
All 50 states · Index 88 B+
Price terms: current enrollment offer, all doses, compounded
Price & billing details
Semaglutide: $79/mo (current enrollment offer, all doses, compounded; usual price $279)
$948 / yr
Check price Read review
33
Lean Meds
All 50 states · Index 84 B
Price terms: $79/mo month-to-month, flat at every dose; the advertised $49 is the 12-month plan
Price & billing details
Semaglutide: $79/mo month-to-month, flat at every dose (the advertised $49 is the 12-month plan)
$948 / yr
Check price Read review
34
NuuVim
All 50 states and DC (some services vary by state) · Index 81 B−
Price terms: all doses, 3-mo plan, new patients only, compounded
Price & billing details
Semaglutide: $79/mo (all doses, 3-mo plan, new patients only, compounded)
$948 / yr
Check price Read review
35
Vivanta Care
All 50 states and D.C. · Index 80 B−
Price terms: starting dose; $169, $229 and $299 at higher dose stages, compounded
Price & billing details
Semaglutide: $79/mo (starting dose; $169, $229 and $299 at higher dose stages, compounded)
$948 / yr
Check price Read review
36
Hello Alpha
Coverage not published · Index 67 C
Price terms: brand Wegovy, plus a separate fee
Price & billing details
Semaglutide: $79/mo (brand Wegovy, plus a separate fee)
$948 / yr
Check price Read review
37
Good Girl Rx
All 50 states · Index 66 C
Price terms: microdose tier, 12-month plan, compounded
Price & billing details
Semaglutide: $79/mo (microdose tier, 12-month plan, compounded)
$948 / yr
Check price Read review
38
RxPepsDirect
28 states · Index 60 C
Price terms: starting dose, visit fee and shipping included, compounded
Price & billing details
Semaglutide: $79/mo (starting dose, visit fee and shipping included, compounded)
$948 / yr
Check price Read review
39
Potere Health MD
1 state · Index 62 C
Price terms: starting dose, compounded
Price & billing details
Semaglutide: $80/mo (starting dose, compounded)
$960 / yr
Check price Read review
40
PreventiveMD
36 states · Index 77 C
Price & billing details
Semaglutide: $83/mo (as low as, term not published, all-in, compounded)
$996 / yr
Check price Read review
41
Vaylen
Terms say 49 states; marketing says all 50 · Index 75 C
Price terms: 12-month program prepaid, compounded
Price & billing details
Semaglutide: $83/mo advertised from (12-month program prepaid, compounded; exact total to confirm)
$996 / yr
Check price Read review
42
Balanced Hormone Health
47 contiguous states (excluding CA; package limits apply) · Index 81 B−
Price terms: ~$85.37/mo equivalent; $197 vial, estimated 10 weeks at starting dose, compounded
Price & billing details
Semaglutide: ~$85.37/mo equivalent ($197 vial, estimated 10 weeks at starting dose, compounded)
$1,024 / yr
Check price Read review
43
Sunlight
All 50 states · Index 84 B
Price terms: starting price, flat monthly, compounded
Price & billing details
Semaglutide: $88/mo (starting price, flat monthly, compounded)
$1,056 / yr
Check price Read review
44
LevelsRx
All 50 states · Index 81 B−
Price terms: starting price, shown as a sale from a struck-through $249
Price & billing details
Semaglutide: $88/mo (starting price, shown as a sale from a struck-through $249; oral liquid from $108, compounded)
$1,056 / yr
Check price Read review
45
Dollar Dad Club
All 50 states (per FAQ; therapy restrictions vary) · Index 83 B
Price terms: compounded, any dose; confirm plan length and renewal
Price & billing details
Semaglutide: $89/mo advertised (compounded, any dose; confirm plan length and renewal)
$1,068 / yr
Check price Read review
46
Mint Med
36 states (published list; confirm yours) · Index 81 B−
Price terms: all doses, month-to-month, compounded
Price & billing details
Semaglutide: $89/mo (all doses, month-to-month, compounded)
$1,068 / yr
Check price Read review
47
Nu Image Medical
All 50 states · Index 74 C
Price terms: as low as, 6-month supply, compounded
Price & billing details
Semaglutide: $89/mo (as low as, 6-month supply, compounded)
$1,068 / yr
Check price Read review
48
Revel RX
Coverage not published · Index 72 C
Price terms: all doses, compounded
Price & billing details
Semaglutide: $89/mo (all doses, compounded)
$1,068 / yr
Check price Read review
49
altRX
Coverage not published · Index 70 C
Price terms: all doses, compounded
Price & billing details
Semaglutide: $89/mo (all doses, compounded)
$1,068 / yr
Check price Read review
50
Enhanced
Not published · Index 65 C
Price terms: starting price, compounded
Price & billing details
Semaglutide: $89/mo (starting price, compounded)
$1,068 / yr
Check price Read review
51
LumiMeds
Coverage not published · Index 57 C
Price terms: first month as low as $39
Price & billing details
Semaglutide: $89/mo (as low as, fixed-term plan, plan length not stated, compounded; first month as low as $39)
$1,068 / yr
Check price Read review
52
LVNG RX
All 50 states · Index 72 C
Price terms: new-patient offer, starting price, compounded
Price & billing details
Semaglutide: $90/mo (new-patient offer, starting price, compounded)
$1,080 / yr
Check price Read review
53
BiltRx
Coverage not published · Index 66 C
Price terms: $81/mo + $9.99/mo required membership
Price & billing details
Semaglutide: $81/mo + $9.99/mo required membership (compounded; consultation and shipping extra)
$1,092 / yr (includes $9.99/mo membership)
Check price Read review
54
Novera MD
Not published · Index 64 C
Price terms: starting price, plan length not shown before the intake, compounded
Price & billing details
Semaglutide: $94.31/mo (starting price, plan length not shown before the intake, compounded)
$1,128 / yr
Check price Read review
55
Mondae
All 50 states · Index 79 C
Price terms: $87 every 28 days month-to-month; the advertised $75 is the three-month prepay
Price & billing details
Semaglutide: $87 every 28 days month-to-month (13 charges a year; the advertised $75 is the three-month prepay)
$1,131 / yr (13 charges)
Check price Read review
56
FMmeds
All 50 states · Index 84 B
Price terms: all doses, physician review and medication included, compounded
Price & billing details
Semaglutide: $95/mo (all doses, physician review and medication included, compounded)
$1,140 / yr
Check price Read review
57
Vitara RX
49 states · Index 87 B+
Price & billing details
Semaglutide: $99/mo
$1,188 / yr
Check price Read review
58
Alan Meds
All 50 states · Index 84 B
Price & billing details
Semaglutide: $99/mo
$1,188 / yr
Check price Read review
59
SnagRx
All states except Louisiana (Nebraska: 19 and older) · Index 81 B−
Price terms: $99/mo month-to-month, same price at every dose; $89 on a 3-month plan, $79 on 6 months, $69 on 12 months
Price & billing details
Semaglutide: $99/mo month-to-month, same price at every dose ($89 on a 3-month plan, $79 on 6 months, $69 on 12 months)
$1,188 / yr
Check price Read review
60
Teleios Health
All 50 states · Index 77 C
Price & billing details
Semaglutide: $99/mo (includes medication, provider visits and shipping, compounded)
$1,188 / yr
Check price Read review

Method · Year figures are the disclosed semaglutide rate × the charges in a year (13 for a plan billed every four weeks), plus any membership the company requires and publishes at a fixed amount (the row says so) — not a quote. Nothing is estimated: dose escalation, first-month promotions, one-time consult and lab fees and unpublished fees are not in the number, so read every row as a floor. Partners are placed first; every row is still ordered by annual cost within its group. Assume any provider we list may compensate us — we may earn a commission at no extra cost to you, which we disclose rather than leave you to infer. See the disclosure and methodology.

$15,881 separates the cheapest semaglutide year from the dearest

Collective anchors the bottom of the ranking at $59/mo for the medication, plus a required $199/year membership billed separately — about $907 across a year. At the other end, Layla runs $16,788 for the same twelve months of the same molecule. That gap does not come from the drug — it comes from the program wrapped around it.

Collective serves 44 states (not AL, CA, LA, MA, MS or WA) — a price you cannot legally buy in your state is not a price. Among providers publishing an all-50-state footprint the cheapest semaglutide year is Tryozi at $948, and that is the number most readers should actually compare against.

What you save by choosing semaglutide over tirzepatide

Pricing the year mostly keeps the order a monthly list already shows; the exception is a plan billed every four weeks, which charges 13 times a year. Where this site earns its keep is the number no sticker-price list computes: at providers we track that disclose both molecules, semaglutide costs less than tirzepatide over a year at every one of them except where the two are priced identically — see semaglutide vs. tirzepatide, cost and efficacy for how the two actually compare on outcomes, not just price. The saving ranges from $-3,600 a year (as low as Nurx) to $4,596 a year (at Docberry), averaging about $893. 19 providers on that list — Amble and Teleios Health and Aspen and Nu Image Medical and Clume Health and InstaRX and Hello Alpha and Iron Med RX and Lighter You and CaliberRx and Gaya Wellness and DadVantage Men's Health and AVArx and Layla and Arc-1 and Lemonaid Health and Mint Medical Clinic and Meto and Thryve — charge the same price for both molecules, so there is no saving there either way.

Provider	Sema / yr	Tirz / yr	Annual saving on sema
Docberry	$2,388	$6,984	$4,596
VirtualCare2Go	$3,348	$7,548	$4,200
Neo Soma Healthcare	$2,587	$6,435	$3,848
Wellorithm	$10,788	$14,388	$3,600
Bioverse	$1,548	$4,788	$3,240
Youth & Soul	$1,788	$4,788	$3,000
MediRX	$2,148	$4,788	$2,640
Breeze Meds	$2,388	$4,788	$2,400
Heva Health	$2,388	$4,788	$2,400
Options Medical Weight Loss	$2,388	$4,788	$2,400
Rivas Medical Weight Loss	$4,788	$7,188	$2,400
FuturHealth	$2,376	$4,740	$2,364
Care Clinics	$1,920	$4,277	$2,357
Wholesome Clinic	$1,908	$4,188	$2,280
Injectco	$2,988	$5,100	$2,112
Henry Meds	$2,148	$4,188	$2,040
Oria Meds	$2,388	$4,428	$2,040
Premium Health	$3,300	$5,340	$2,040
Fidelity Medical Clinic	$2,587	$4,537	$1,950
MadeMed	$2,868	$4,788	$1,920
FitRx	$3,564	$5,388	$1,824
Zealthy	$3,564	$5,388	$1,824
AM Rx	$3,564	$5,388	$1,824
Heally	$1,788	$3,588	$1,800
OrderlyMeds	$1,788	$3,588	$1,800
Synergy Rx	$2,388	$4,188	$1,800
Knownwell	$1,788	$3,588	$1,800
Walgreens Weight Management	$1,788	$3,588	$1,800
LifeMD	$3,576	$5,376	$1,800
PrideRx	$2,976	$4,776	$1,800
GetRelief Rx	$2,508	$4,308	$1,800
ZipHealth	$1,788	$3,588	$1,800
Maven Clinic	$3,588	$5,388	$1,800
Try Ageless	$1,188	$2,988	$1,800
Levers Health	$2,964	$4,752	$1,788
Lean Rx	$3,192	$4,788	$1,596
GobyMeds	$2,028	$3,588	$1,560
EOS Health	$2,028	$3,588	$1,560
NuBloom	$1,788	$3,348	$1,560
Unique Physique	$1,908	$3,468	$1,560
Neuvé Health	$2,628	$4,188	$1,560
Invigor Medical	$2,700	$4,200	$1,500
Call-On-Doc	$3,000	$4,500	$1,500
Tonik Wellness	$2,700	$4,188	$1,488
DrBrainRx	$1,848	$3,288	$1,440
Transparent Meds	$2,748	$4,188	$1,440
LeanDose	$1,908	$3,348	$1,440
Fitish	$2,628	$4,068	$1,440
Tru2u	$2,700	$4,140	$1,440
MedLeanRx	$1,788	$3,228	$1,440
HealthOn	$3,060	$4,500	$1,440
The Calibrate Clinic	$2,580	$3,948	$1,368
Yucca Health	$1,752	$3,096	$1,344
Kongo	$1,428	$2,748	$1,320
Rx.com	$2,100	$3,420	$1,320
Näky	$2,220	$3,540	$1,320
Fridays	$2,988	$4,308	$1,320
Pallas Health	$2,587	$3,887	$1,300
NiceRx	$1,937	$3,237	$1,300
Contour Health	$1,300	$2,600	$1,300

What the annual figure leaves out

Every number above is the disclosed rate times the charges in a year (13, not 12, for a plan billed every four weeks) — we invent no cost the ranking does not record. That multiplier also does not tell you where a program is available. These providers do not publish an all-50-state footprint:

Collective — 44 states (not AL, CA, LA, MA, MS or WA)
Ivy Rx — Not published; confirm eligibility
Hello Alpha — Coverage not published
RxPepsDirect — 28 states
Potere Health MD — 1 state
PreventiveMD — 36 states
Balanced Hormone Health — 47 contiguous states (excluding CA; package limits apply)
Mint Med — 36 states (published list; confirm yours)
Revel RX — Coverage not published
altRX — Coverage not published
Enhanced — Not published
LumiMeds — Coverage not published
BiltRx — Coverage not published
Novera MD — Not published
Strut Health — 49 states (not Arkansas)
Vitara RX — 49 states
SnagRx — All states except Louisiana (Nebraska: 19 and older)
Harbor — Coverage not published
Liv Body — Not published
HealthHub — Coverage not published
Zeuss — Coverage not published
AbundRX — Coverage not published
Luci — Coverage not published
Trinity Meds — Coverage not published
Livea — 4 states
Medi-Weightloss — Coverage not published
Try Ageless — Not published
Thryve — Not disclosed
Medical Health Institute — Coverage not published
RxPros — Coverage not published
Factor Health MD — Coverage not published
Stealth Health — Coverage not published
Lttl — Coverage not published
Contour Health — 46 states (not MI, MS, KY or AR)
OurView Health — 46 states plus DC (excludes AR, CT, HI and NJ)
Blis MD — 29 states
Belle Health — Confirm state eligibility before enrolling
JustAnswer Weight Loss — Coverage not published
Lumen Meds — Coverage not published
Bliv — Coverage not published
Nucific — Coverage not published
Trava Health — Confirm availability in your state before paying
Measured — Coverage not published
Pomegranate Health — Coverage not published
VevaRX — 36 states
Luma Health Co — 30 states
BeyondMD — Coverage not published
Citizen Meds — Coverage not published
VitaStir — Coverage not published
Woodwork — Coverage not published
Brightmeds — 38 states + DC
DoctorAdam — 44 states
Novi — Coverage not published
Roboclinic — Coverage not published
One80Rx — Not published
Alternate Health Club — Coverage not published
Metaboost Rx — Coverage not published
Yes Clinic — Not published
Nuform Health — Coverage not published
Liberty — Coverage not published

Dose escalation, a promotional first month that resets, one-time consult or lab fees and any fee a company does not publish are also not in the number (a required membership with a published price is) — the method is the same one behind the true monthly cost of GLP-1, and the cost calculators will run your own numbers.

Cheapest semaglutide, answered

What is the cheapest semaglutide provider over a full year?: At its disclosed rate, plus any required published fee, Collective carries the lowest twelve-month semaglutide cost we track — $59/mo for the medication, plus a required $199/year membership billed separately works out to about $907 a year. It serves 44 states (not AL, CA, LA, MA, MS or WA), which is the catch. Among providers publishing an all-50-state footprint, the lowest twelve-month figure is Tryozi at about $948.
Is cheap compounded semaglutide the same as Wegovy or Ozempic?: No. Wegovy and Ozempic are Novo Nordisk's FDA-approved brand semaglutide — Wegovy for chronic weight management, Ozempic for type 2 diabetes, both reviewed by the FDA for safety, effectiveness and quality. Wegovy's approximate US cash list price is around $1,349/mo. Compounded semaglutide, which is almost everything here, is a different product prepared by a compounding pharmacy — same active ingredient in most cases, but not FDA-approved and not FDA-reviewed as a finished drug.
How much less does semaglutide cost than tirzepatide at the same provider?: Across the providers we track that disclose both molecules, choosing semaglutide over tirzepatide saves $-3,600 to $4,596 a year, averaging about $893. 19 providers on that list price both molecules identically, so the saving there is zero.
Does pricing a full year change which provider is cheapest?: Sometimes. A plan billed monthly is twelve charges a year, so it keeps the order a monthly list would show; a plan billed every four weeks is thirteen charges, so its year costs one charge more than its sticker suggests. What can also move a row on the page you're looking at is placement: partners are surfaced first, as they are on every ranking on this site (see our disclosure), and every row is still ordered strictly by twelve-month cost within its group. The dollar figure next to each provider is never adjusted either way.
What does the twelve-month semaglutide figure leave out?: It is the disclosed semaglutide rate times the charges in a year (13, not 12, for a plan billed every four weeks), plus any membership or care fee the company requires and publishes at a fixed monthly or yearly amount, such as a $199 annual membership. Nothing is estimated. It does not model dose escalation into a higher price tier, a promotional first month that resets, one-time consultation or lab fees, optional add-ons, or a fee the company does not publish. Every one of those pushes the real figure up, never down.

The other rankings

Cheapest tirzepatide over 12 months — the same annual method, for readers who already know they want tirzepatide instead.
Compounded semaglutide, plainly explained — what compounded semaglutide is and its FDA status, plus a top-picks version of this same ranking.
Wegovy & Ozempic cost — the brand-first answer, if FDA-approved semaglutide is what you actually want.
Cheapest GLP-1 providers that are actually worth it — partners listed first, each with its Cost-Efficiency Index score across both molecules.
Cheapest GLP-1 for a full year — the broader annual ranking, not narrowed to one molecule.

Prices are each provider's public disclosures at last check and move fast — confirm before you buy. Compounded medications are not FDA-approved. Not medical advice; see our medical disclaimer.