Annual price comparison · updated October 2026
The cheapest GLP-1 over twelve months, not over one.
Compare disclosed compounded semaglutide prices over a full year, including required published fees. Compounded drugs are not FDA-approved. Four-week plans count as 13 charges. Partners appear first; providers are ordered by annual cost within each group.
Listed firstPartner
Collective
Index 65 C · 44 states (not AL, CA, LA, MA, MS or WA)
$907/ yr (includes $199/yr membership)
Compare annual costs
Priced programs · sorted by 12-month cost
Partners appear first; providers are ordered by annual cost within each group. Four-week plans count as 13 charges. See our disclosure.
- 01
Collective
44 states (not AL, CA, LA, MA, MS or WA) · Index 65 C
Price terms: $59/mo for the medication, plus a required $199/year membership billed separately
Price & billing details
Semaglutide: $59/mo for the medication, plus a required $199/year membership billed separately
$907 / yr (includes $199/yr membership)
- 02
Embody
All 50 states · Index 77 C
Price terms: sale price, compounded
Price & billing details
Semaglutide: $79/mo (sale price, compounded)
$948 / yr
- 03
CoreAge Rx
All 50 states · Index 94 A
Price & billing details
Semaglutide: $99/mo
$1,188 / yr
- 04
Eden
All 50 states · Index 94 A
Price terms: all doses, compounded
Price & billing details
Semaglutide: $99/mo (all doses, compounded)
$1,188 / yr
- 05
Strut Health
49 states (not Arkansas) · Index 87 B+
Price & billing details
Semaglutide: From $99/mo lozenge, $129/mo injection (auto-refill)
$1,188 / yr
- 06
Lttl
Coverage not published · Index 61 C
Price terms: $99 per 4 weeks
Price & billing details
Semaglutide: $99 per 4 weeks (compounded, auto-refill)
$1,287 / yr (13 charges)
- 07
Belle Health
Confirm state eligibility before enrolling · Index 71 C
Price & billing details
Semaglutide: From $109/mo (compounded; confirm your plan at checkout)
$1,308 / yr
- 08
Peter MD
Varies by treatment — semaglutide not in AL, AK, HI or ID, tirzepatide not in AL or ID; additional reported restrictions need confirmation · Index 72 C
Price terms: $149/mo first-time
Price & billing details
Semaglutide: $149/mo first-time (Level 1), $139/mo returning (Level 2)
$1,788 / yr
- 09
bmiMD
All 50 states · Index 83 B
Price terms: $119/mo on a prepaid 12-month plan
Price & billing details
Semaglutide: $159/mo month to month ($119/mo on a prepaid 12-month plan)
$1,908 / yr
- 10
Sprout Health
44 states (not AL, AR, CA, LA, MS or ND) · Index 80 B−
Price terms: $149 per 4 weeks; $99/mo on a prepaid 12-month plan
Price & billing details
Semaglutide: $149 per 4 weeks ($99/mo on a prepaid 12-month plan)
$1,937 / yr (13 charges)
- 11
Bodybuilding Health+
50 states claimed, no list published · Index 74 C
Price & billing details
Semaglutide: $179/mo month-to-month; $159.33 on three months, $158 on six and $141.50 on twelve
$2,148 / yr
- 12
HealthRX
All 50 states · Index 74 C
Price terms: all doses, compounded
Price & billing details
Semaglutide: $190/mo (all doses, compounded)
$2,280 / yr
- 13
RNK Health
Not published (US only) · Index 59 C
Price & billing details
Semaglutide: From $197/mo (compounded, month to month)
$2,364 / yr
- 14
ShedRx (Shed)
All 50 states · Index 87 B+
Price terms: $159 on a 12-month plan
Price & billing details
Semaglutide: $199/mo ($159 on a 12-month plan)
$2,388 / yr
- 15
Enhance MD
40 states + DC · Index 76 C
Price terms: first month $112
Price & billing details
Semaglutide: $212/mo (first month $112)
$2,544 / yr
- 16
Found
All 50 states · Index 92 A−
Price terms: insurance-linked
Price & billing details
Semaglutide: $199/mo (insurance-linked)
$2,587 / yr (13 charges)
- 17
Luvo Health
50 states claimed, no list published · Index 66 C
Price terms: $209 per 4 weeks
Price & billing details
Semaglutide: $209 per 4 weeks (injection, compounded)
$2,717 / yr (13 charges)
- 18
RxSpan MD
All 50 states · Index 83 B
Price & billing details
Semaglutide: $249/mo month-to-month for the injection; $219 on three months, $199 on six and $194 on twelve
$2,988 / yr
- 19
SkinnyRx
Most states · Index 74 C
Price terms: $249/mo month to month after a $99 first month; $199/mo on a 12-month plan
Price & billing details
Semaglutide: $249/mo month to month after a $99 first month ($199/mo on a 12-month plan)
$2,988 / yr
- 20
Direct Meds
Not disclosed · Index 71 C
Price terms: sublingual, 90-day supply billed monthly
Price & billing details
Semaglutide: $249/mo (sublingual, 90-day supply billed monthly)
$2,988 / yr
- 21
MyDrHank
Not published; program excludes KS, LA, MS, NM, ND, WV · Index 65 C
Price terms: yearly prepay: $171 / $178
Price & billing details
Semaglutide: $249/mo oral, $259/mo injectable (yearly prepay: $171 / $178)
$2,988 / yr
- 22
Oak
45 states (list not published) · Index 77 C
Price terms: same price at every dose; $200/mo on a 3-month supply paid upfront
Price & billing details
Semaglutide: $250/mo (same price at every dose; $200/mo on a 3-month supply paid upfront)
$3,000 / yr
- 23
Willow
35 states + Puerto Rico · Index 68 C
Price & billing details
Semaglutide: $299/mo (compounded, month to month)
$3,588 / yr
- 24
MEDGm
All 50 states · Index 67 C
Price terms: the advertised $179 is the first month only, after an automatically applied coupon
Price & billing details
Semaglutide: $299/mo month-to-month (the advertised $179 is the first month only, after an automatically applied coupon)
$3,588 / yr
- 25
Wellorithm
All 50 states and D.C. · Index 72 C
Price terms: fine print ties the price to a 3-month plan paid upfront
Price & billing details
Semaglutide: $899/mo (brand Wegovy; fine print ties the price to a 3-month plan paid upfront)
$10,788 / yr
- 26
Sesame Care
Nationwide · Index 86 B
Price terms: that rate needs a 12-month commitment
Price & billing details
Semaglutide: $149/mo medication + $59/mo care subscription (that rate needs a 12-month commitment)
Price not disclosed — sorted last
- 27
Gala Health
50 states claimed, no list published · Index 71 C
Price & billing details
Semaglutide: Compounded from $129/mo (plan length not stated); brand Ozempic $1,299/mo
Price not disclosed — sorted last
- 28
WellMedr
50 states claimed, no list published · Index 54 C
Price terms: Not disclosed — sale price only, no standing rate
Price & billing details
Semaglutide: Not disclosed — sale price only, no standing rate
Price not disclosed — sorted last
- 29
EverPrime
Varies by treatment and state; confirmed during intake · Index 50 C
Price terms: optional membership pricing
Price & billing details
Semaglutide: $249 standard one-month plan; optional membership pricing
Price not disclosed — sorted last
- 30
YourEra
Coverage not published · Index 43 C
Price terms: Not disclosed — advertised from $79/mo with a new-patient coupon
Price & billing details
Semaglutide: Not disclosed — advertised from $79/mo with a new-patient coupon; the standing monthly rate shows only after you enter an email
Price not disclosed — sorted last
- 31
HumeCare+
Coverage not published · Index 42 C
Price terms: $199/mo on a 3-month plan with a welcome credit applied; medication and dose not stated; plus a separate fee at enrollment and every refill, never published
Price & billing details
Semaglutide: $199/mo on a 3-month plan with a welcome credit applied (medication and dose not stated; plus a separate fee at enrollment and every refill, never published; compounded)
Price not disclosed — sorted last
- 32
NextMeds
All 50 states · Index 87 B+
Price terms: dated enrollment offer, all doses, compounded; ends October 31
Price & billing details
Semaglutide: $49/mo (dated enrollment offer, all doses, compounded; ends October 31)
$588 / yr
- 33
Ivy Rx
Not published; confirm eligibility · Index 76 C
Price & billing details
Semaglutide: $77/mo from (standard shared GLP-1 injection headline, compounded; confirm selected plan)
$924 / yr
- 34
Tryozi
All 50 states · Index 88 B+
Price terms: current enrollment offer, all doses, compounded
Price & billing details
Semaglutide: $79/mo (current enrollment offer, all doses, compounded; usual price $279)
$948 / yr
- 35
Lean Meds
All 50 states · Index 84 B
Price terms: $79/mo month-to-month, flat at every dose; the advertised $49 is the 12-month plan
Price & billing details
Semaglutide: $79/mo month-to-month, flat at every dose (the advertised $49 is the 12-month plan)
$948 / yr
- 36
NuuVim
All 50 states and DC (some services vary by state) · Index 81 B−
Price terms: all doses, 3-mo plan, new patients only, compounded
Price & billing details
Semaglutide: $79/mo (all doses, 3-mo plan, new patients only, compounded)
$948 / yr
- 37
Vivanta Care
All 50 states and D.C. · Index 80 B−
Price terms: starting dose; $169, $229 and $299 at higher dose stages, compounded
Price & billing details
Semaglutide: $79/mo (starting dose; $169, $229 and $299 at higher dose stages, compounded)
$948 / yr
- 38
Hello Alpha
Coverage not published · Index 67 C
Price terms: brand Wegovy, plus a separate fee
Price & billing details
Semaglutide: $79/mo (brand Wegovy, plus a separate fee)
$948 / yr
- 39
Good Girl Rx
All 50 states · Index 66 C
Price terms: microdose tier, 12-month plan, compounded
Price & billing details
Semaglutide: $79/mo (microdose tier, 12-month plan, compounded)
$948 / yr
- 40
RxPepsDirect
28 states · Index 60 C
Price terms: starting dose, visit fee and shipping included, compounded
Price & billing details
Semaglutide: $79/mo (starting dose, visit fee and shipping included, compounded)
$948 / yr
- 41
Potere Health MD
1 state · Index 62 C
Price terms: starting dose, compounded
Price & billing details
Semaglutide: $80/mo (starting dose, compounded)
$960 / yr
- 42
PreventiveMD
36 states · Index 77 C
Price & billing details
Semaglutide: $83/mo (as low as, term not published, all-in, compounded)
$996 / yr
- 43
Vaylen
Terms say 49 states; marketing says all 50 · Index 75 C
Price terms: 12-month program prepaid, compounded
Price & billing details
Semaglutide: $83/mo advertised from (12-month program prepaid, compounded; exact total to confirm)
$996 / yr
- 44
Balanced Hormone Health
47 contiguous states (excluding CA; package limits apply) · Index 81 B−
Price terms: ~$85.37/mo equivalent; $197 vial, estimated 10 weeks at starting dose, compounded
Price & billing details
Semaglutide: ~$85.37/mo equivalent ($197 vial, estimated 10 weeks at starting dose, compounded)
$1,024 / yr
- 45
Sunlight
All 50 states · Index 84 B
Price terms: starting price, flat monthly, compounded
Price & billing details
Semaglutide: $88/mo (starting price, flat monthly, compounded)
$1,056 / yr
- 46
LevelsRx
All 50 states · Index 81 B−
Price terms: starting price, shown as a sale from a struck-through $249
Price & billing details
Semaglutide: $88/mo (starting price, shown as a sale from a struck-through $249; oral liquid from $108, compounded)
$1,056 / yr
- 47
Dollar Dad Club
All 50 states (per FAQ; therapy restrictions vary) · Index 83 B
Price terms: compounded, any dose; confirm plan length and renewal
Price & billing details
Semaglutide: $89/mo advertised (compounded, any dose; confirm plan length and renewal)
$1,068 / yr
- 48
Mint Med
36 states (published list; confirm yours) · Index 81 B−
Price terms: all doses, month-to-month, compounded
Price & billing details
Semaglutide: $89/mo (all doses, month-to-month, compounded)
$1,068 / yr
- 49
Nu Image Medical
All 50 states · Index 74 C
Price terms: as low as, 6-month supply, compounded
Price & billing details
Semaglutide: $89/mo (as low as, 6-month supply, compounded)
$1,068 / yr
- 50
Revel RX
Coverage not published · Index 72 C
Price terms: all doses, compounded
Price & billing details
Semaglutide: $89/mo (all doses, compounded)
$1,068 / yr
- 51
altRX
Coverage not published · Index 70 C
Price terms: all doses, compounded
Price & billing details
Semaglutide: $89/mo (all doses, compounded)
$1,068 / yr
- 52
Enhanced
Not published · Index 65 C
Price terms: starting price, compounded
Price & billing details
Semaglutide: $89/mo (starting price, compounded)
$1,068 / yr
- 53
LumiMeds
Coverage not published · Index 57 C
Price terms: first month as low as $39
Price & billing details
Semaglutide: $89/mo (as low as, fixed-term plan, plan length not stated, compounded; first month as low as $39)
$1,068 / yr
- 54
LVNG RX
All 50 states · Index 72 C
Price terms: new-patient offer, starting price, compounded
Price & billing details
Semaglutide: $90/mo (new-patient offer, starting price, compounded)
$1,080 / yr
- 55
BiltRx
Coverage not published · Index 66 C
Price terms: $81/mo + $9.99/mo required membership
Price & billing details
Semaglutide: $81/mo + $9.99/mo required membership (compounded; consultation and shipping extra)
$1,092 / yr (includes $9.99/mo membership)
- 56
Novera MD
Not published · Index 64 C
Price terms: starting price, plan length not shown before the intake, compounded
Price & billing details
Semaglutide: $94.31/mo (starting price, plan length not shown before the intake, compounded)
$1,128 / yr
- 57
Mondae
All 50 states · Index 79 C
Price terms: $87 every 28 days month-to-month; the advertised $75 is the three-month prepay
Price & billing details
Semaglutide: $87 every 28 days month-to-month (13 charges a year; the advertised $75 is the three-month prepay)
$1,131 / yr (13 charges)
- 58
FMmeds
All 50 states · Index 84 B
Price terms: all doses, physician review and medication included, compounded
Price & billing details
Semaglutide: $95/mo (all doses, physician review and medication included, compounded)
$1,140 / yr
- 59
Vitara RX
49 states · Index 87 B+
Price & billing details
Semaglutide: $99/mo
$1,188 / yr
- 60
Alan Meds
All 50 states · Index 84 B
Price & billing details
Semaglutide: $99/mo
$1,188 / yr
Method · Year figures are the disclosed semaglutide rate × the charges in a year (13 for a plan billed every four weeks), plus any membership the company requires and publishes at a fixed amount (the row says so) — not a quote. Nothing is estimated: dose escalation, first-month promotions, one-time consult and lab fees and unpublished fees are not in the number, so read every row as a floor. The Cost-Efficiency Index is our own and is printed unmodified — no provider can buy a point. Partners are placed first; every row is still ordered by annual cost within its group. Assume any provider we list may compensate us — we may earn a commission at no extra cost to you, which we disclose rather than leave you to infer. See the disclosure and methodology.
$16,200 separates the cheapest year from the dearest
NextMeds anchors the bottom of the ranking at $49/mo (dated enrollment offer, all doses, compounded; ends October 31) — about $588 across a year. At the other end, Layla runs $16,788 for the same twelve months of the same molecule. Nothing about the medication differs by $16,200; what differs is the program wrapped around it.
The bottom of a price-sorted ranking is also where the trade-offs live. NextMeds publishes an all-50-state footprint, which is unusual at that price.
What a headline monthly price leaves out
Four things routinely sit between the number on a landing page and the number on your statements: a promotional first month that resets in month two, dose escalation into a higher price tier as you titrate, a 6- or 12-month commitment quoted as though it were month-to-month, and fees charged alongside the medication — consult, labs, shipping, a coaching membership you cannot unbundle. A required membership the company publishes at a fixed price is already in the readout above, and the row says so; the rest are not, because they are not figures the company states up front. All four push the real cost up, which is why every row here is a floor rather than a forecast. The arithmetic, step by step, is in the true monthly cost of GLP-1, and the cost calculators will run your own numbers.
“Which GLP-1 is cheapest” has two answers
The molecule decides more of your annual bill than the brand of telehealth does. Across this site the cheapest disclosed semaglutide line is $49/mo (dated enrollment offer, all doses, compounded; ends October 31) from NextMeds; the cheapest tirzepatide line is $69/mo for the medication, plus the same required $199/year membership from Collective. They are rarely the same desk, and the gap between them over twelve months is real money. Pick the molecule on evidence and tolerability first — our semaglutide vs tirzepatide value guide weighs that trade — then price the year for the molecule you chose, not for the cheapest line on the page. If tirzepatide is the molecule you land on, its own dedicated annual board is at cheapest tirzepatide over 12 months.
Annual GLP-1 cost, answered
- What is the cheapest GLP-1 program over a full year?
- At its disclosed rate, plus any required published fee, NextMeds carries the lowest twelve-month cost on the bench — $49/mo (dated enrollment offer, all doses, compounded; ends October 31) works out to about $588 a year. Coverage is the catch: it serves All 50 states. Among providers publishing an all-50-state footprint, the lowest twelve-month figure is NextMeds at about $588.
- Which GLP-1 medication is the cheapest?
- Semaglutide, almost everywhere. Across this site the cheapest disclosed semaglutide line is $49/mo (dated enrollment offer, all doses, compounded; ends October 31) (NextMeds) against $69/mo for the medication, plus the same required $199/year membership (Collective) for tirzepatide — and the same provider is rarely cheapest on both. Decide the molecule first, then price the year for that molecule.
- Why rank by twelve-month cost instead of monthly price?
- Because a GLP-1 is an annual purchase, not a one-month one — the result depends on staying on it. A first-month teaser you abandon in spring costs more than a slightly higher flat rate you can sustain. Twelve months is the shortest window in which a step-up, a commitment tier or a membership fee shows up in the number.
- What does this twelve-month figure not include?
- It is the disclosed rate times the charges in a year (13, not 12, for a plan billed every four weeks), plus any membership or care fee the company requires and publishes at a fixed monthly or yearly amount, such as a $199 annual membership. Nothing is estimated. It does not model dose escalation into a higher price tier, a promotional first month that resets, one-time consultation or lab fees, optional add-ons, or a fee the company does not publish. Every one of those pushes the real figure up, never down.
The other rankings
- Cheapest GLP-1 providers that are actually worth it — partners listed first, each with its Cost-Efficiency Index score across both molecules.
- Cheapest tirzepatide over 12 months — this same annual method, isolated to tirzepatide, if that's the molecule you've decided on.
- Cheapest semaglutide over 12 months — the molecule-first cut for semaglutide, including the Wegovy/Ozempic brand split.
- Zepbound cost — for the brand-name answer first, if FDA-approved tirzepatide is what you actually want.
Also useful: what a GLP-1 costs without insurance, or line two finalists up side by side.
Prices are each provider's public disclosures at last check and move fast — confirm before you buy. Not medical advice; see our medical disclaimer.