Sesame Care review
The widest real brand-name GLP-1 access on the board — a LegitScript- and BBB-recognized national marketplace running since 2018 that dispenses FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro and Rybelsus, not compounded copies.
- Semaglutide
- $149/mo (brand)
- Tirzepatide
- Brand (Zepbound)
- Coverage
- Nationwide
- Brand-name
- Yes
The Index scorecard
Sesame Care scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Widest brand-name formulary we list — Wegovy pen and pill, Zepbound, Ozempic, Mounjaro and oral Rybelsus, all FDA-approved rather than compounded
- Established national marketplace operating since 2018, with LegitScript certification and BBB recognition
- Wegovy pill starts around $149/mo, and oral routes are available for the needle-averse
The tradeoffs
- Two-part cost — the medication price is separate from a platform subscription, so the all-in monthly runs above the $149 headline
- A generalist telehealth marketplace, not a dedicated GLP-1 program
The bottom line
Best for: People who specifically want FDA-approved brand-name medication (including the Wegovy pill or oral Rybelsus) from an established, verified marketplace and will budget for a two-part cost. The widest real brand-name GLP-1 access on the board — a LegitScript- and BBB-recognized national marketplace running since 2018 that dispenses FDA-approved Wegovy, Zepbound, Ozempic, Mounjaro and Rybelsus, not compounded copies.
Ranked #6 of 30 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 29 other providers we've modeled, in Cost-Efficiency Index order.
- #5Breeze Meds— The most transparent operator in our partner tier — all-50 compounded GLP-1 with NPI-verifiable named physicians, named pharmacies and LegitScript backing, so you can actually audit who's behind the script.86/100
- #7Eden— You pay a premium per month, but you buy back certainty: all-50 access and high-disclosure clinical oversight that hold their value.86/100
- #8Found— The cheapest identical price on both molecules nationwide — unbeatable raw cost-per-month, capped only by a coaching subscription you can't fully unbundle.88/100
- #9Sprout Health— Low-friction and well-priced — $149 compounded semaglutide and $199 tirzepatide from a LegitScript-certified operator, with a brand Wegovy/Zepbound path if you want to step up.85/100
- #10Shed (tryshed.com)— The widest set of formats in the partner tier — compounded semaglutide (~$159) and tirzepatide (~$239) injections plus drops, lozenges and microdosing, or a brand Wegovy pill (~$149) — all behind a named care team and a 120-day guarantee. (Not to be confused with ShedRx, a separate brand on this board.)85/100
- #11Trimi Health— The board's cheapest all-50 combined ticket — $99 semaglutide and $125 tirzepatide, both disclosed up front so the year-one math is clean. The catch is a thinner oversight paper trail, which is exactly why it sits mid-pack rather than higher.85/100
Every other program we track (23)
- #1 CoreAge Rx94
- #2 Invigor Medical88
- #3 Ondra Health90
- #4 ShedRx87
- #12 AgelessRx85
- #13 Vitara RX87
- #14 NewSelf87
- #15 Gimme Care87
- #16 Precision Telemed87
- #17 Effecty86
- #18 Kongo86
- #19 Curex85
- #20 PepHaūs85
- #21 Alan Meds84
- #22 bmiMD84
- #23 Ro84
- #24 Hims & Hers83
- #25 Care Bare Rx80
- #26 Live Vital82
- #27 Piper82
- #28 Henry Meds81
- #29 NP2GO79
- #30 Primary Clinic (Direct GLP)77
Pricing, states and verification reflect Sesame Care's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Sesame Care's site. Not medical advice; see our disclosure.