Fifty 410 Review: Price, Pros & Cons
Fifty 410 is a direct-to-consumer compounded-GLP-1 telehealth service.
In this review
Compounded drugs are not FDA-approved. Treatment requires a clinician's assessment. Understand compounded GLP-1 treatment.
Prices at a glance
- Semaglutide
- $199/moAll doses, compounded
- Tirzepatide
- $133/moStarting dose, 3-month plan, compounded
- Coverage
- Coverage not published
- Brand-name
- Not confirmed
Semaglutide · estimated annual cost
$2,388
Tirzepatide · estimated annual cost
$1,596
Who Fifty 410 may suit
Shoppers who want a one-time-payment compounded tirzepatide bundle and understand the 'per month' figure is really a 3-month lump sum.
Where the value is
- No recurring subscription — you pay once per order and are not auto-billed
- Transparent per-tier tirzepatide totals ($399/$499/$549) shown alongside the per-month math, so the real charge is visible if you read past the headline
- Free overnight/2-day shipping and refrigerated packaging included in every tier
- Afterpay/Affirm and FSA/HSA payment flexibility offered
The tradeoffs
- Tirzepatide's advertised '$133/month' is a 3-month prepay of $399 charged in one transaction, not a monthly recurring price — the cheapest advertised number is not what most shoppers will assume
- Semaglutide has no discounted multi-month tier and, at $199 flat, actually costs more per month than tirzepatide's cheapest bundle
- Compounding pharmacy is never named — only a generic '503A & 503B' claim
- No served-states list, no named medical director, and no LegitScript certification
- FDA issued Aspen Aesthetics dba Fifty 410 a warning letter in February 2026; the letter is public in FDA's warning-letter database
What Fifty 410 charges
Fifty 410 lists compounded semaglutide from $199 a month. Compounded tirzepatide is cheaper per month on paper, $133, but only on a three-month program paid in one charge of $399 for the starting dose tier. The high-dose tier works out to $183 a month, $549 for three months.
| Price | How it's charged | |
|---|---|---|
| Semaglutide | from $199/mo | per order |
| Tirzepatide, starting tier | $133/mo | $399 for 3 months, upfront |
| Tirzepatide, high-dose tier | $183/mo | $549 for 3 months, upfront |
The tirzepatide price climbs with the dose tier, so check which tier your provider puts you on. A monthly tirzepatide option is also shown, at a higher price than the three-month rate.
The price includes the provider consultation and free one- to two-day refrigerated shipping. There's no membership fee and no insurance billing. You can pay with Afterpay, Affirm, or an FSA or HSA card.
Considering Fifty 410?
Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.
You don't pay until you're prescribed
Fifty 410's intake is a five-minute online form, and no credit card is needed to start. A licensed provider reviews it. If you're prescribed, you get a secure payment link to choose your pharmacy and supply length, and only then are you charged.
Fifty 410 is a telehealth platform; independent compounding pharmacies prepare the medication, and Fifty 410 doesn't name them. You get written and video instructions for injecting, and only your provider can change your dose. It doesn't list the states it serves, so confirm yours in the intake. Compounded medications are not FDA-approved.
The refund window is short
Fifty 410 publishes its refund rules as a simple table:
- After you pay, before compounding starts: full refund. The cancellation counts only if Fifty 410 confirms it arrived before the pharmacy began work.
- After compounding starts, or once shipped: no routine refund.
- Pharmacy can't fill the order: the unfilled amount is refunded.
- Wrong, damaged, lost or warm shipment: reviewed for a replacement, refund or credit. Report it within 48 hours of delivery with photos.
Since pharmacies start quickly, cancel right away if you change your mind after paying. Approved refunds are processed within five business days and reach a card five to ten business days after that.
The Index scorecard
Fifty 410 scored on our six Cost-Efficiency Index factors. See the methodology.
The bottom line
Fifty 410 is a direct-to-consumer compounded-GLP-1 telehealth service.
Compare the total cost of other GLP-1 programs and alternatives to Fifty 410 before deciding. A clinician should help you choose the right treatment.
Other programs to compare with Fifty 410
These are partners: we may earn a commission if you sign up, at no cost to you.
OakPartner
Semaglutide modeled $250/mo · Tirzepatide modeled $300/mo
Oak's order form charges $250 a month for compounded semaglutide and $300 for tirzepatide at every dose, with no subscription and brand-name pens on the same menu, while its marketing pages advertise figures from $89 to $190 that the form does not offer.
EmbodyPartner
Semaglutide modeled $79/mo · Tirzepatide modeled $129/mo
Embody sells compounded semaglutide from $79 a month and tirzepatide from $129, marked as sale prices, with prescribers from the OpenLoop Health network.
Enhance MDPartner
Semaglutide modeled $212/mo · Tirzepatide modeled $280/mo
Enhance MD charges $212 a month for compounded semaglutide and $280 for tirzepatide at every dose, with lab work every six months included; the first month is $100 less.
Compare with other providers
The providers whose Cost-Efficiency Index scores sit closest to Fifty 410's. See the alternatives to Fifty 410.
- Better MedSpa— Better MedSpa is a Chicago-based, statewide-Illinois med spa and telehealth practice under medical director Dr. Brett Brechner, DO, offering semaglutide and tirzepatide with an in-person location in Lincoln Park, Chicago.59/100
- eMed— eMed, the at-home testing company, sells individuals a brand-name Wegovy program: a $49 screening blood test, a $149.99 monthly membership, and the pill or pen from $149.99 a month.59/100
- System Labs— System Labs is a peptide and longevity telehealth service selling NAD+, glutathione, sermorelin and a MIC+B12 injection; it doesn't sell semaglutide, tirzepatide or any GLP-1 medication.59/100
- Mixx Health & Wellness— Mixx Health & Wellness offers a compounded GLP-1/GIP program through Elevis Medical Group, with a named medical director and Promise Pharmacy listed as a dispensing partner.58/100
- Bon Health— Bon Health is a physician-led GLP-1 weight-loss telehealth service selling compounded semaglutide and tirzepatide on commitment tiers.58/100
- Spry— Spry offers weekly GLP-1 injections with four-week refills and online provider review. Its advertised starting prices are $199 for semaglutide and $299 for tirzepatide; confirm the price at your prescribed dose.58/100
Pricing, states and verification reflect Fifty 410's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Fifty 410's site. Not medical advice; see our disclosure.