Enhance MD review
The clearest tiered price ladder in this ranking — separate published lines for semaglutide, tirzepatide, a microdose tier and a sema+tirz combo — with lab work built into every tier.
- Semaglutide
- $212/mo (first month $112)
- Tirzepatide
- $280/mo (first month $180)
- Coverage
- Not disclosed
- Brand-name
- Compounded only
Semaglutide · modeled / year
$2,544
Tirzepatide · modeled / year
$3,360
Pricing verified August 2026
The Index scorecard
Enhance MD scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Fully published, dose-flat tiered pricing — sema $212/mo, tirz $280/mo, microdose $169/mo, sema+tirz combo $322/mo — no quiz or quote wall
- The rate does not climb as your dose is titrated up, unlike per-mg pricing elsewhere in this ranking
- Routine lab work at the 6-month mark plus ongoing provider messaging is bundled into the price, not sold separately
- An adjacent NAD+ longevity line sits on the same account for readers who want it
The tradeoffs
- Compounded only — no FDA-approved brand-name route (no Wegovy, Ozempic, Mounjaro or Zepbound)
- No oral or sublingual GLP-1 option (injection only)
- The $212 semaglutide and $280 tirzepatide rates are the ONGOING price — the homepage's $112/$180 figures are a first-month-only teaser
- States served are not publicly listed — confirm coverage before signing up
- Above this ranking's ~$144 median on both molecules
The bottom line
Best for: Shoppers who want to see every price on the ladder before they commit, value dose-flat billing and routine lab monitoring, and don't need a brand-name or oral route. The clearest tiered price ladder in this ranking — separate published lines for semaglutide, tirzepatide, a microdose tier and a sema+tirz combo — with lab work built into every tier.
Ranked #43 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Enhance MD.
- #42Renlo Health— A price lock, a named prescriber and a named pharmacy — and a headline that is the actual monthly rate rather than a prepay divided down.78/100
- #44PreventiveMD— PreventiveMD is a physician-guided telehealth platform for GLP-1 weight loss and peptide therapy, offering compounded semaglutide from $83/mo all-in and compounded tirzepatide from $97/mo all-in.77/100
- #45Rx.com— Prints "No automatic renewals" on the plan card and names the pharmacy that dispenses, with a street address — then advertises another drug's prepay rate.77/100
- #46HealthRX— Publishes its entire term ladder as machine-readable data — and advertises the twelve-month rung, so the price on the tin is roughly half the price you pay month to month.74/100
- #47Pallas Health— Prices both molecules openly and bills them in 12-week blocks — $597 and $897 up front, with no monthly option to fall back on.74/100
- #48EverSlim— EverSlim is a US telehealth program selling doctor-prescribed compounded GLP-1 medication delivered to the door, with compounded semaglutide from $117 a month and compounded tirzepatide from $140 a month.76/100
The 19 programs nearest this one
Pricing, states and verification reflect Enhance MD's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Enhance MD's site. Not medical advice; see our disclosure.