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Grade C76/100 IndexPartner

Enhance MD Review: Price, Pros & Cons

By The WeighLab Bench, Tools & Data Desk

Enhance MD charges $212 a month for compounded semaglutide and $280 for tirzepatide at every dose, with lab work every six months included; the first month is $100 less.

In this review

Compounded drugs are not FDA-approved. Treatment requires a clinician's assessment. Understand compounded GLP-1 treatment.

Check Enhance MD prices Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.

Prices at a glance

Semaglutide
$212/moFirst month $112
Tirzepatide
$280/moFirst month $180
Coverage
40 states + DC
Brand-name
Not confirmed

Semaglutide · estimated annual cost

$2,544

Tirzepatide · estimated annual cost

$3,360

Who Enhance MD may suit

Shoppers who want flat pricing that doesn't rise with the dose, routine lab monitoring and a semaglutide-plus-tirzepatide combo option, and who don't need a brand-name or oral route.

Where the value is

  • Every plan is priced on the homepage before any quiz: semaglutide $212, tirzepatide $280, a semaglutide-plus-tirzepatide combo $322 and microdosed tirzepatide $169
  • The monthly price stays the same as your dose goes up
  • Lab testing every six months and ongoing provider messaging are built into the price rather than sold separately
  • A NAD+ line sits on the same account, from $169 a month, for readers who want it

The tradeoffs

  • Compounded only, with no brand-name Wegovy, Ozempic, Mounjaro or Zepbound
  • No oral or sublingual GLP-1, so every option is an injection
  • The $112 and $180 on the homepage are first-month prices; from month two you pay $212 and $280
  • Available in 40 states and D.C. so far; not in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina or Tennessee
  • Semaglutide at $212 a month costs more than at many programs we track

How Enhance MD prices its plans

Enhance MD charges one flat price per drug, whatever your dose. The first month costs $100 less, and the regular price starts with the second. The related EverPrime review covers another offering from Enhance MD, LLC with separate medication and optional membership pricing; its terms and rates differ.

PlanFirst monthAfter that
Semaglutide ("GLP-1 Core")$112$212
Tirzepatide ("GLP-1 Advanced")$180$280
Semaglutide plus tirzepatide ("GLP-1 Elite")$222$322
Microdosed tirzepatide, 1 mg a week—$169

Memberships renew every 28 days, so a year has 13 charges rather than 12. At $212, a year of semaglutide comes to about $2,656 after the discounted first month. The price includes lab work, provider visits, medication and two-day priority shipping. Enhance MD takes major credit cards but not HSA or FSA cards, and it doesn't bill insurance.

Considering Enhance MD?

Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.

Enhance MD pays us a commission if you start there. This does not change its Index score.

Labs come first

Enhance MD requires bloodwork before it prescribes. After the intake, you book a draw at a Quest Diagnostics location. The panel covers a comprehensive metabolic panel, lipids, thyroid (TSH) and HbA1c. Results usually post to your account within one to two business days. Then you schedule a video visit with a provider to go over them.

Labs repeat every six months while you're enrolled, at no extra cost. That makes the start slower than an intake-only service, so plan for a few extra days before your first shipment.

Who prescribes and who fills it

Enhance MD itself is a management company. The physicians and nurse practitioners work for two medical groups, Enhance Wellness PC and iThriveMD PC. Its site names Dr. Erik Stark as medical director.

Prescriptions go to one of three pharmacies Enhance MD works with, Tru Meds Rx, Strive Pharmacy or Pharmacy Hub, which ship to a physical address. You can also send the prescription to a pharmacy of your choice, but then that pharmacy bills you for the drug at its own price.

Where it's available, and canceling

Enhance MD currently serves 40 states and D.C. It isn't available in Alabama, Arkansas, Georgia, Hawaii, Louisiana, Mississippi, Missouri, North Dakota, South Carolina or Tennessee.

You can pause or cancel at any time by emailing or calling support. If a provider finds you ineligible during onboarding, you get a full refund of your first payment. Prescription products can't be returned once shipped.

The Index scorecard

Enhance MD scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month65/100
Price Transparency88/100
Nationwide Access66/100
Formulation Options74/100
Clinical Oversight85/100
Contract Flexibility82/100

The bottom line

Enhance MD charges $212 a month for compounded semaglutide and $280 for tirzepatide at every dose, with lab work every six months included; the first month is $100 less.

Compare the total cost of other GLP-1 programs and alternatives to Enhance MD before deciding. A clinician should help you choose the right treatment.

Other programs to compare with Enhance MD

These are partners: we may earn a commission if you sign up, at no cost to you.

  • CollectivePartner

    Semaglutide modeled $75.58/mo · Tirzepatide modeled $85.58/mo

    Collective sells compounded semaglutide at $59 and tirzepatide at $69 a month, both genuinely medication prices, on top of a $199 annual membership that is required, auto-renewing and not refundable.

  • LttlPartner

    Semaglutide modeled $107.25/mo · Tirzepatide modeled $161.42/mo

    Lttl charges $99 every four weeks for compounded semaglutide and $149 for tirzepatide on a cancel-anytime auto-refill, with small discounts for longer supplies.

  • CoreAge RxPartner

    Semaglutide modeled $99/mo · Tirzepatide modeled $149/mo

    CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.

Compare with other providers

The providers whose Cost-Efficiency Index scores sit closest to Enhance MD's. See the alternatives to Enhance MD.

Explore more provider reviews

Pricing, states and verification reflect Enhance MD's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Enhance MD's site. Not medical advice; see our disclosure.

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