Evidence review
What Compounded GLP-1 Actually Costs Per Month
A cost guide to compounded semaglutide and tirzepatide: real disclosed ranges of roughly $65–$349/mo, what drives the spread, and how to model your own number.
Section index04
Ask five telehealth sites what compounded GLP-1 costs and you will get five different answers, several of them intro rates that will not last. This is a plain cost guide: the real disclosed ranges across the providers we track, what moves the number up or down, and how to model what you will personally pay for a year.
CoreAge Rx
$99/mo sema · $149/mo tirz
- Semaglutide
- $99/mo
- Tirzepatide
- $149/mo
- Coverage
- All 50 states
- Brand-name
- Compounded only
- Modeled / yr
- $1,188
Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
Read the full CoreAge Rx review →Assume any provider we list may compensate us — we may earn a commission at no cost to you. It never moves the Index. See our disclosure.
Strut Health
87/100- Semaglutide
- From $99/mo sublingual, $149/mo injectable
- Tirzepatide
- From $199/mo either route
Regulatory note: FDA warning letter issued to Strut Health, LLC dba Strut, February 2026.
The headline range: about $65 to $349 per month
Across the compounded GLP-1 providers on the Cost-Efficiency Index, disclosed monthly prices run from roughly $74 at the low end to about $349 at the high end (per each provider's published pricing, last reviewed 2026). The cheapest sticker here is OrderlyMeds at $74 for semaglutide — and that figure is a two-month starter plan open only to patients new to GLP-1s, against a standing rate of $149, which is exactly why sticker price alone is misleading. One more thing belongs next to that name rather than one click away on its review: the FDA issued a warning letter to OrderlyMeds LLC dba OrderlyMeds in June 2026, and it is on the public record in the agency's own warning-letter database, which our review of OrderlyMeds links directly. We still list the company and still quote its price; a superlative that puts a name at the top of a cost guide should not be the one place that fact is missing. In the value tier, verified all-50-state providers such as Vitara RX at $99 semaglutide and Ondra Health at $93 show what a low price plus nationwide access actually looks like.
What drives the spread
Four things move your monthly cost:
Molecule. Semaglutide is usually cheaper than tirzepatide; some providers list both at the same price, others charge a clear premium for tirzepatide. We compare them in semaglutide vs tirzepatide, and rank every provider's tirzepatide line by twelve-month cost in the cheapest tirzepatide ranking. If you want the FDA-approved brand instead, Zepbound's real cost is the place to start.
Dose. Compounded pricing is often flat per month regardless of dose at a given provider, but not always — some tiers rise as your dose escalates, which matters because most people titrate upward over their first few months.
Provider positioning. Budget operators compete on raw price; premium ones charge more for stronger disclosure, oversight, or brand access. A mid-market $149–$199 flat price from an all-50, verified provider is often the best true value even though it is not the lowest sticker.
Bundling. Some prices include clinician visits and shipping; others add fees. Always confirm what the number includes.
Billing cadence. Check whether "per month" means a calendar month at all. A plan billed every four weeks charges thirteen times a year, not twelve, which quietly adds a full extra cycle to any annual figure you calculate from the monthly one. Where a provider sells prepaid blocks instead, check the division: The Edit's three- and six-month blocks divide back to the per-month figures it advertises exactly, which is not something every published ladder survives.
Sticker price is not annual cost
The number on the landing page is a starting point, not a total. Two things routinely make your real cost higher: teaser rates that step up after the first month, and dose escalation that can shift you into a higher price tier. A $99 intro that becomes $199 in month two costs about $2,090 over a year, not $1,188 — a difference that changes which provider is actually cheapest. There is a third version worth naming, because it looks like neither: a price that is monthly-shaped but is really a prepaid year divided by twelve. Try Ageless does this three times on one page — its hero reads "$159/mo from" and its two "entry price" cards read "from $199/mo" and "from $249/mo", and all three are the twelve-month rungs, payable in full up front. The month-to-month prices on the same page are $199, $279 and $349. We walk through the full method in the true monthly cost of GLP-1.
Model your own number
Do not trust a single sticker — build the year. Use the cost calculators to plug in a provider's disclosed price, add any month-two step-up, and multiply out 12 months. Then compare finalists on total annual cost side by side with the compare tool. One note on what you are buying: compounded GLP-1 medication is not FDA-approved, and the FDA does not verify the safety, effectiveness, or quality of compounded drugs1 — so weigh price against a verifiable pharmacy, not in isolation. The compounded market exists at this price largely because these molecules spent time on the FDA drug-shortage list, which permits compounding under defined conditions2; we cover what that means for you in is compounded semaglutide legit and safe, and specifically for tirzepatide, is compounded tirzepatide still legal covers what narrowed once that molecule came off the shortage list. A structurally different oral drug sometimes gets lumped into this same compounded-cost conversation on cost grounds alone — see orforglipron, the FDA-approved oral GLP-1 pill, for why it isn't actually a compounded-market option today. For the ranked cash price across every provider we track, see the cheapest GLP-1 ranking, or the full provider review index for the cost breakdown behind each one.
Frequently asked questions
How much does compounded semaglutide cost per month?
Across the providers we track, disclosed compounded semaglutide runs from roughly $65 to about $249 per month, with several verified all-50-state options in the $93–$149 range (per each provider's published pricing, last reviewed 2026).
Why is the cheapest provider not always the best value?
The lowest sticker often comes from providers serving only a few states or from intro rates that step up after month one. Value is price plus access, verification, and a modelable full-year total.
Does the monthly price go up as my dose increases?
At many providers the price is flat per month regardless of dose, but some tier pricing by dose. Since most people titrate upward early on, confirm whether escalation moves you into a higher tier.
References
- U.S. Food and Drug Administration (2024). Compounding and the FDA: Questions and Answers. U.S. Food and Drug Administration. https://www.fda.gov/drugs/human-drug-compounding/compounding-and-fda-questions-and-answers
- U.S. Food and Drug Administration (2024). FDA Drug Shortages Database. U.S. Food and Drug Administration. https://www.accessdata.fda.gov/scripts/drugshortages/
Medical disclaimer: This content is for general educational purposes only and is not medical advice, diagnosis, or treatment. Always consult a licensed healthcare professional before starting, stopping, or changing any treatment.
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