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Ranked #346 · Grade C

SkyRx review

SkyRx is a telehealth platform selling compounded semaglutide (tirzepatide listed as 'coming soon') behind a headline $199/mo price that is actually a 12-month prepaid commitment rather than a monthly cash rate.

Visit SkyRx Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.
Semaglutide
$199/mo (compounded)
Tirzepatide
Not disclosed
Coverage
Coverage not published
Brand-name
Compounded only

Semaglutide · modeled / year

$2,388

Pricing verified August 2026

The Index scorecard

SkyRx scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month51/100
Price Transparency86/100
Nationwide Access24/100
Formulation Options64/100
Clinical Oversight76/100
Contract Flexibility20/100

Where the value is

  • Simple, single headline price displayed on the weight-loss page
  • Claims LegitScript certification
  • Straightforward telehealth intake flow
  • Free/discreet home delivery mentioned

The tradeoffs

  • The '$199/mo' price is a 12-month prepay rate, not a cancel-anytime monthly price -- a major disclosure trap
  • Tirzepatide not yet available ('coming soon'), so half the category is unpriced
  • No medical director named
  • No specific compounding pharmacy named, and not available in all 50 states with no published list

The bottom line

Best for: Shoppers willing to commit and prepay a full year upfront in exchange for a lower blended monthly rate. SkyRx is a telehealth platform selling compounded semaglutide (tirzepatide listed as 'coming soon') behind a headline $199/mo price that is actually a 12-month prepaid commitment rather than a monthly cash rate.

Ranked #346 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.

Compare with other providers

All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to SkyRx.

The 24 programs nearest this one

Pricing, states and verification reflect SkyRx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on SkyRx's site. Not medical advice; see our disclosure.

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