Skip to content
WeighLab
Menu

Best-value alternatives

Alternatives to SkyRx

SkyRx scores 55/100 on our Cost-Efficiency Index (ranked #346 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.

Read the SkyRx review →CoreAge Rx vs SkyRx →
  1. Our #1 pick
    01A

    CoreAge Rx

    Ranked #1

    Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded
    Visit CoreAge Rx CoreAge Rx vs SkyRx →
  2. 02C

    Rivas Medical Weight Loss

    Ranked #345

    Rivas Medical Weight Loss is primarily a 15-location in-person clinic chain in Maryland, Virginia, and Florida run by Dr. Paul Rivas, with a newer telehealth option for compounded semaglutide and tirzepatide.

    Sema
    $399/mo (all doses, plus a separate fee, compounded)
    Tirz
    $599/mo (all doses, plus a separate fee, compounded)
    Coverage
    3 states
    Brand
    Compounded
    Visit Rivas Medical Weight Loss Rivas Medical Weight Loss vs SkyRx →
  3. 03C

    Revive Meds

    Ranked #344

    Revive Meds is a telehealth weight-loss brand offering compounded semaglutide and tirzepatide injections nationwide, but it discloses zero pricing publicly -- cost only appears after intake.

    Sema
    Not disclosed
    Tirz
    Not disclosed
    Coverage
    All 50 states
    Brand
    Yes
    Visit Revive Meds Revive Meds vs SkyRx →
  4. 04C

    PeptidesRx

    Ranked #343

    PeptidesRx (PeptidesRx LLC, Fort Worth, TX) is a legitimate clinical telehealth platform, not a research-chemical vendor: it requires a licensed-provider consultation before any prescription, compounds through PCAB-accredited U.S.

    Sema
    $321/mo (10 mg dose, compounded)
    Tirz
    $576/mo (40 mg dose, compounded)
    Coverage
    Multi-state
    Brand
    Compounded
    Visit PeptidesRx PeptidesRx vs SkyRx →
  5. 05C

    Optimized Health

    Ranked #342

    Optimized Health (optimized.care) is a small, single-prescriber telehealth practice serving five states (Missouri, Iowa, Kansas, Utah, Washington) plus an in-person Joplin, MO clinic.

    Sema
    $200/mo (starting dose, plus a separate fee, compounded)
    Tirz
    $250/mo (starting dose, bundle, compounded)
    Coverage
    5 states
    Brand
    Compounded
    Visit Optimized Health Optimized Health vs SkyRx →
  6. 06C

    Nucore Health

    Ranked #341

    Nucore Health is a nationwide (all 50 states, per its own claim) DTC telehealth platform selling compounded semaglutide plus B12 at a flat $299/month regardless of dose, alongside anti-aging, sexual health, and hair-restoration products.

    Sema
    $299/mo (all doses, compounded)
    Tirz
    Not disclosed
    Coverage
    Multi-state
    Brand
    Compounded
    Visit Nucore Health Nucore Health vs SkyRx →
  7. 07C

    Mint Medical Clinic

    Ranked #340

    Mint Medical Clinic is primarily an in-person medical clinic with locations in Sandy and Layton, Utah.

    Sema
    $299/mo (starting dose, compounded)
    Tirz
    $299/mo (starting dose, compounded)
    Coverage
    1 state
    Brand
    Compounded
    Visit Mint Medical Clinic Mint Medical Clinic vs SkyRx →
  8. 08C

    MediRX

    Ranked #339

    MediRx is a weight-loss telehealth storefront that white-labels OpenLoop Health's clinician network for actual prescribing and pharmacy fulfillment.

    Sema
    $149/mo (starting dose, compounded)
    Tirz
    $199/mo (starting dose, compounded)
    Coverage
    Multi-state
    Brand
    Compounded
    Visit MediRX MediRX vs SkyRx →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

← All comparisons & head-to-heads