PlexusDx review
PlexusDx is a nationwide compounded-GLP-1 telehealth platform offering both semaglutide (injection or oral tablet) and tirzepatide from published starting prices, LegitScript certified.
- Semaglutide
- $149/mo (all doses, compounded)
- Tirzepatide
- $249/mo (all doses, compounded)
- Coverage
- All 50 states
- Brand-name
- Compounded only
Semaglutide · modeled / year
$1,788
Tirzepatide · modeled / year
$2,988
Pricing verified August 2026
The Index scorecard
PlexusDx scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- LegitScript Certified, stated directly on the homepage
- Both injection and oral tablet formats for semaglutide from the same starting price
- All 50 states served
- 10% first-protocol promo code (GETSTARTED) published openly
- CLIA-certified labs and 503A pharmacies referenced, though not individually named
The tradeoffs
- 'Starts at' pricing — the page does not disclose what higher doses cost, so $149/$249 is a floor, not what most patients settling into a maintenance dose will pay
- No named prescriber, medical director, or specific compounding pharmacy
- Genetic-panel upsell (Precision Peptide) is marketed alongside the core GLP-1 offer
The bottom line
Best for: Shoppers who want a published starting price with an oral semaglutide option, all 50 states. PlexusDx is a nationwide compounded-GLP-1 telehealth platform offering both semaglutide (injection or oral tablet) and tirzepatide from published starting prices, LegitScript certified.
Ranked #27 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to PlexusDx.
- #22Ro— The widest formulary — brand-name and oral access, with a named CMO — but the $149/mo (or $74/mo prepaid annual) membership fee is separate from the drug's own opaque, insurance-dependent price.84/100
- #23Lean Meds— Lean Meds charges $79 a month for compounded semaglutide and $109 for tirzepatide, flat at every dose, names the four pharmacies that fill the prescriptions, and advertises a $49 figure that is really its twelve-month rate.84/100
- #24Hims & Hers— Nationwide reach and a slick app at a mid-market semaglutide price — but an undisclosed tirzepatide price leaves part of the value equation blank.83/100
- #25Care Bare Rx— A LegitScript-certified, HIPAA-compliant multi-service platform bundling weight loss with hair, TRT, sexual health and NAD+ — both oral (Rybelsus, oral tirzepatide) and injectable compounded routes, real brand Ozempic from ~$705/mo, and coverage across all 50 states plus Puerto Rico, but the 3-month plan is a real trap: it costs more per month than either month-to-month or the 6-month plan.80/100
- #26Live Vital— A very low $99 semaglutide nationwide, with tirzepatide disclosed too — cheap and all-50, but without LegitScript verification.82/100
- #28No BS RX— Twenty-four prices on one public page, four dispensing pharmacies named with street addresses, and a no-intro-rate promise the arithmetic on its own page supports.82/100
The 23 programs nearest this one
- #29 Curex81
- #30 Henry Meds81
- #31 Luma Health Co81
- #32 Trimi Health78
- #33 REMEVi80
- #34 Vaylen80
- #35 NP2GO79
- #36 KERNX Health79
- #37 Mondae79
- #38 Idgie Health79
- #39 Trava Health78
- #40 Welling Health78
- #41 FMmeds78
- #42 Renlo Health78
- #43 Enhance MD75
- #44 PreventiveMD77
- #45 Rx.com77
- #46 HealthRX74
- #47 Pallas Health74
- #48 EverSlim76
- #49 Maves76
- #50 NiceRx76
- #51 Vytora Health76
Pricing, states and verification reflect PlexusDx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on PlexusDx's site. Not medical advice; see our disclosure.