PlexusDx review
PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states.
- Semaglutide
- $149/mo (starting dose, compounded)
- Tirzepatide
- $249/mo (starting dose, compounded)
- Coverage
- All 50 states
- Brand-name
- Compounded only
Semaglutide · modeled / year
$1,788
Tirzepatide · modeled / year
$2,988
The Index scorecard
PlexusDx scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Licensed providers available in all 50 states
- Range of options including low-cost microdose GLP-1 from $129/mo
- Optional Precision Peptide genetic panel adds a personalization angle
- Independent clinician review via state-licensed telehealth platform
- Compounded medications from state-licensed pharmacies
The tradeoffs
- Compounded medications only; no FDA-approved brand options
- Specific compounding pharmacies not named
- Genetic-panel upsell may not add clinical value for everyone
- Tirzepatide pricing from $249/mo is higher than budget rivals
- No insurance accepted
The bottom line
Best for: Shoppers wanting nationwide compounded GLP-1 with optional genetic-test personalization. PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states.
Ranked #64 of 492 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 491 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to PlexusDx.
- #63Luma Health Co— Luma Health Co is a nurse-practitioner-led virtual weight-loss and wellness clinic founded by Tiffani McKnight, FNP-C.74/100
- #65Trava Health— Houston-based DTC telehealth offering compounded semaglutide+B12 and tirzepatide+B12 through SIX named 503A compounding pharmacy partners disclosed on Trava's own Terms + Telehealth Consent pages…74/100
- #66ZYP Medical— ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states.74/100
- #67Synergy Rx— Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact — at prices its own site never shows.71/100
- #68Gala Health— Every dose at one published price, with the whole price list visible before you hand over an email — but the only terms it sells on are a yearly subscription at $179 or a three-month plan at $199, so there is no monthly number here to compare with anyone else's.71/100
- #69Direct Meds— The widest set of routes on this board — sublingual and injection on both semaglutide and tirzepatide, every SKU priced in the open — sold well above the median, on a plan that only ever bills against a 90-day supply.71/100
The 19 programs nearest this one
Pricing, states and verification reflect PlexusDx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on PlexusDx's site. Not medical advice; see our disclosure.