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Ranked #65 · Grade C

He & She MD review

He & She MD is a nationwide telehealth weight-loss clinic offering compounded semaglutide and tirzepatide (injectable, oral, or microdose) plus brand-name access.

Visit He & She MD Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.
Semaglutide
$199/mo (month to month, compounded; every lower rate is a prepaid term)
Tirzepatide
$299/mo (month to month, compounded; every lower rate is a prepaid term)
Coverage
All states except Louisiana (GLP-1)
Brand-name
Yes

Semaglutide · modeled / year

$2,388

Tirzepatide · modeled / year

$2,388

Pricing verified August 2026

The Index scorecard

He & She MD scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month51/100
Price Transparency78/100
Nationwide Access86/100
Formulation Options90/100
Clinical Oversight85/100
Contract Flexibility33/100

Where the value is

  • Compounded semaglutide and tirzepatide (injectable or oral), with brand-name access to Ozempic, Wegovy, and Zepbound also offered
  • Named pharmacy (F&F Pharmacies Inc DBA Jungle Jim's Pharmacy, Fairfield OH) and named CMO (Dr. Ozita Cooper, MD)
  • Free expedited shipping and unlimited board-certified clinician access
  • LegitScript certified, with third-party batch testing disclosed for sterile compounds
  • Only charged if medication is actually prescribed

The tradeoffs

  • Its own FAQ says the pharmacy it names holds a license in 44 US states, none in California, Nevada, New Jersey, North Carolina, Texas, Massachusetts, Mississippi, New Hampshire, West Virginia or Delaware, and “cannot dispense sterile compounds” — while the same FAQ says GLP-1s ship everywhere except Louisiana. Injectable GLP-1s are sterile compounds, and the site never says which of its two pharmacies covers the gap
  • The uniform '$199 to start' banner across all three tracks obscures that only injectable semaglutide holds at $199 ongoing — oral semaglutide rolls to $239/mo and injectable tirzepatide rolls to $289/mo after the first 6-month cycle
  • The named pharmacy is licensed in only 44 states (cannot serve CA, NV, NJ, NC, TX, MA, MS, NH, WV, DE) while the site separately claims coverage in 'all U.S. states except Louisiana' — an unreconciled gap of roughly 9 states
  • Recurring 6-month billing cycle, not simple month-to-month
  • Compounded GLP-1s are not FDA-approved finished products
  • Does not ship to Louisiana or to PO boxes

The bottom line

Best for: Shoppers comparing injectable semaglutide specifically, where the advertised $199 genuinely is the standing price — not oral semaglutide or tirzepatide, which roll higher after 6 months. He & She MD is a nationwide telehealth weight-loss clinic offering compounded semaglutide and tirzepatide (injectable, oral, or microdose) plus brand-name access.

Ranked #65 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.

Compare with other providers

All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to He & She MD.

The 18 programs nearest this one

Pricing, states and verification reflect He & She MD's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on He & She MD's site. Not medical advice; see our disclosure.

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