He & She MD review
He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral) plus a microdose option, with brand-name…
- Semaglutide
- $139/mo (starting dose, promotional rate, compounded)
- Tirzepatide
- $199/mo (starting dose, compounded)
- Coverage
- All 50 states
- Brand-name
- Yes
Semaglutide · modeled / year
$1,668
Tirzepatide · modeled / year
$2,388
The Index scorecard
He & She MD scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Transparent intro pricing: injectable GLP-1 from $139/month, oral from $199, microdose from $99
- Compounded semaglutide and tirzepatide (injectable or oral) plus brand access to Ozempic, Wegovy, Zepbound
- Only charged if medication is prescribed; no hidden fees
- Free expedited shipping and unlimited board-certified clinician access
- GLP-1 coaching, nutrition guidance, and in-app progress tracking
The tradeoffs
- Compounded GLP-1s are not FDA-approved finished products (per the site FDA disclaimer)
- Does not ship to Louisiana or to PO boxes
- Introductory pricing rises after the 6-month (or 3-month microdose) plan
- Cash-pay model — insurance billing not indicated
The bottom line
Best for: Cost-first shoppers who want transparent low intro-priced GLP-1 (injectable, oral, or microdose) with brand-name access. He & She MD is a nationwide telehealth weight-loss clinic offering doctor-prescribed GLP-1 medications: compounded semaglutide and tirzepatide (injectable or oral) plus a microdose option, with brand-name…
Ranked #60 of 492 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 491 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to He & She MD.
- #64PlexusDx— PlexusDx (plexusdx.com) is a US GLP-1 telehealth platform offering compounded weight-loss medications with licensed providers in all 50 states.74/100
- #65Trava Health— Houston-based DTC telehealth offering compounded semaglutide+B12 and tirzepatide+B12 through SIX named 503A compounding pharmacy partners disclosed on Trava's own Terms + Telehealth Consent pages…74/100
- #66ZYP Medical— ZYP Medical is a men's-health-oriented telehealth practice prescribing compounded GLP-1 medications for weight loss across six states.74/100
- #67Synergy Rx— Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact — at prices its own site never shows.71/100
- #68Gala Health— Every dose at one published price, with the whole price list visible before you hand over an email — but the only terms it sells on are a yearly subscription at $179 or a three-month plan at $199, so there is no monthly number here to compare with anyone else's.71/100
- #69Direct Meds— The widest set of routes on this board — sublingual and injection on both semaglutide and tirzepatide, every SKU priced in the open — sold well above the median, on a plan that only ever bills against a 90-day supply.71/100
Pricing, states and verification reflect He & She MD's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on He & She MD's site. Not medical advice; see our disclosure.