Open Water Rx review
Open Water Rx is a self-pay telehealth platform selling compounded semaglutide ($199/mo standing, $159/mo with a promo code), tirzepatide ($339/mo standing, $219/mo with a different promo code), and an oral GLP-1 option.
- Semaglutide
- $199/mo (promotional rate, plus a separate fee, compounded)
- Tirzepatide
- $339/mo (compounded)
- Coverage
- Coverage not published
- Brand-name
- Compounded only
Semaglutide · modeled / year
$2,388
Tirzepatide · modeled / year
$4,068
Pricing verified August 2026
The Index scorecard
Open Water Rx scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Names four specific 503A compounding pharmacies (RedRock, HealthWarehouse, Precision Compounding, Triad Rx) — most competitors disclose zero
- Pricing is genuinely all-inclusive — clinician review, medication, and shipping bundled with no separate visit fee
- LegitScript certification seals displayed
- HSA/FSA eligible and 'no insurance required,' stated plainly
The tradeoffs
- The lower, more prominent $159/$219 figures depend on promo codes (SEMASUMMER, FOUNDER) stacked on top of stated $199/$339 standing prices — unclear whether these codes are permanent
- A '12-Week Plan' at $169/month strongly implies a multi-month prepay requirement, but the page never states the actual upfront total
- No specific mg dose is published for the standard semaglutide/tirzepatide tiers
- No named medical director found; coverage is described only as 'over 25 states' with no full published list
The bottom line
Best for: Cost-first shoppers who want all-inclusive compounded GLP-1 pricing from four named 503A pharmacies, if you qualify for the promo codes. Open Water Rx is a self-pay telehealth platform selling compounded semaglutide ($199/mo standing, $159/mo with a promo code), tirzepatide ($339/mo standing, $219/mo with a different promo code), and an oral GLP-1 option.
Ranked #379 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Open Water Rx.
- #381Strive Pharmacy— Strive Pharmacy is a 503A/503B compounding pharmacy that primarily serves OTHER healthcare providers and clinics — not a direct-to-consumer telehealth site.53/100
- #382T2D.com— T2D.com is primarily a type-2-diabetes/pre-diabetes telehealth platform ('Life in Control™') that also runs a GLP-1 weight-loss offer.53/100
- #383ZipHealth— ZipHealth is a compounded-GLP-1 telehealth platform delivering to 19 named states, advertising personalized programs 'from $149/month' but layering on a $79 clinical service fee that recurs on repeat visits, not just at signup.53/100
- #384Joi + Blokes— Joi + Blokes is a hormone-first telehealth platform running parallel women's (Joi) and men's (Blokes) programs, now including compounded GLP-1s at $199/mo semaglutide and $299/mo tirzepatide (after a discounted $99/$149 first month).52/100
- #385Alegro Health— Alegro Health is a McKinney, Texas telehealth practice offering compounded GLP-1 weight-loss care, advertised through a $199 8-week semaglutide-plus-B12 starter promo available only in select states.52/100
- #386CVS MinuteClinic— CVS MinuteClinic is a general retail urgent-care service (in-store and some virtual) that can prescribe FDA-approved branded GLP-1s for weight loss 'when appropriate' as one of dozens of services it offers.52/100
The 18 programs nearest this one
- #380 Reset Solutions53
- #387 EllieMD52
- #388 Hormonally Balanced52
- #389 Lyfe Rx52
- #390 PCOS Sisters52
- #391 Remi Meds52
- #392 Shape Vantage52
- #393 Vyora Wellness52
- #394 Empower Pharmacy51
- #395 BioGlow Health51
- #396 Bloom MD51
- #397 Gaya Wellness51
- #398 JRNYS51
- #399 LIV by WellNow51
- #400 LVNG RX51
- #401 Noom51
- #402 Onyx Weight Loss51
- #403 TRT Nation51
Pricing, states and verification reflect Open Water Rx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Open Water Rx's site. Not medical advice; see our disclosure.