Trillium Meds review
Trillium Meds is a small, Portland-OR-based telehealth platform connecting patients to independent licensed providers and compounding pharmacies for GLP-1 therapy, serving all 50 states plus Puerto Rico.
- Semaglutide
- $159/mo (all doses, compounded)
- Tirzepatide
- $249/mo (all doses, compounded)
- Coverage
- All 50 states
- Brand-name
- Compounded only
Semaglutide · modeled / year
$1,908
Tirzepatide · modeled / year
$2,988
Pricing verified August 2026
The Index scorecard
Trillium Meds scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Discloses both a real month-to-month rate ($159/$249) and the 3-month prepay rate, rather than only advertising the lower prepay number
- LegitScript certified, all 50 states plus Puerto Rico, with a real street address published
- Syringes and alcohol wipes included; Klarna and Affirm financing available
- Small, owner-operated support model with direct email/phone contact
The tradeoffs
- The lowest advertised rate ($119/mo semaglutide, ~$200/mo tirzepatide) requires a $357 or $599 upfront 3-month payment, not a standing monthly charge
- Partner pharmacy names are referenced in the FAQ structure but were not visible in the page text pulled this session — re-verify before citing a specific pharmacy
- Small single-operator platform; no labs, coaching, or clinical monitoring beyond the telehealth Rx and pharmacy fulfillment
The bottom line
Best for: Cost-first shoppers who want all-50-state compounded GLP-1 with a real month-to-month option and a cheaper 3-month prepay path. Trillium Meds is a small, Portland-OR-based telehealth platform connecting patients to independent licensed providers and compounding pharmacies for GLP-1 therapy, serving all 50 states plus Puerto Rico.
Ranked #71 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Trillium Meds.
- #50NiceRx— NiceRx is a compounded GLP-1 telehealth platform charging $199/mo for semaglutide and $299/mo for tirzepatide on an ongoing month-to-month basis (first month discounted to $99 and $199 respectively).76/100
- #51Vytora Health— Vytora Health (Wasef Health, PC) is a 50-state-plus-DC telehealth platform selling flat-rate compounded semaglutide and tirzepatide alongside retail-priced brand-name Mounjaro and Zepbound ($1,399/mo each).76/100
- #52Rylo Health— Rylo Health is a compounded GLP-1/NAD+/peptide telehealth platform operating in all 50 states through Lone Star Virtual Health PLLC and dispensing via VialsRX in Houston, TX.75/100
- #53Synergy Rx— Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact — at prices its own site never shows.72/100
- #54Peter MD— One account across six verticals — TRT, ED, weight loss, GLP-1, men's hair loss and NAD+ — from a physician-prescribed telehealth brand running since 2021, at a renewal price ($249/mo tirzepatide) well above its own $149 first-month headline.72/100
- #55EdgeRx— The best clinical documentation of any newly added row — a named Chief Medical Advisor and a named 503A pharmacy — but it's a men's-only platform, not a fit for every reader.74/100
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Pricing, states and verification reflect Trillium Meds's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Trillium Meds's site. Not medical advice; see our disclosure.