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Best-value alternatives

Alternatives to Open Water Rx

Open Water Rx scores 53/100 on our Cost-Efficiency Index (ranked #379 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.

Read the Open Water Rx review →CoreAge Rx vs Open Water Rx →
  1. Our #1 pick
    01A

    CoreAge Rx

    Ranked #1

    Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded
    Visit CoreAge Rx CoreAge Rx vs Open Water Rx →
  2. 02C

    Nuform Health

    Ranked #378

    Nuform Health is a Troy, Michigan-based multi-vertical telehealth brand (TRT, GLP-1, NAD+, peptides) whose GLP-1 products are compounded vitamin blends sold only as mandatory multi-month prepaid plans.

    Sema
    $129/mo (starting dose, compounded)
    Tirz
    $199/mo (starting dose, compounded)
    Coverage
    Multi-state
    Brand
    Yes
    Visit Nuform Health Nuform Health vs Open Water Rx →
  3. 03C

    Mojoon

    Ranked #377

    Mojoon is a bilingual (Chinese/English) DTC telehealth platform selling compounded injectable and oral semaglutide, LegitScript-claimed and licensed across 48 states (excluding New Mexico and Mississippi).

    Sema
    $350/mo (0.25 mg dose, compounded)
    Tirz
    Not disclosed
    Coverage
    Multi-state
    Brand
    Compounded
    Visit Mojoon Mojoon vs Open Water Rx →
  4. 04C

    Mevo Health

    Ranked #376

    Mevo Health is a direct-pay telemedicine platform selling compounded semaglutide ('as low as $199') and tirzepatide ('as low as $259') under named Medical Director Dr. David Wasef, head of the Mevo Provider Network.

    Sema
    $199/mo (starting dose, compounded)
    Tirz
    $259/mo (starting dose, quarterly plan, compounded)
    Coverage
    Multi-state
    Brand
    Compounded
    Visit Mevo Health Mevo Health vs Open Water Rx →
  5. 05C

    Metabolyz

    Ranked #375

    Metabolyz is a nationwide GLP-1 telehealth program (semaglutide, tirzepatide, microdosing) that explicitly withholds all pricing from its public pages, disclosing cost only after a consultation begins.

    Sema
    Not disclosed
    Tirz
    Not disclosed
    Coverage
    All 50 states
    Brand
    Compounded
    Visit Metabolyz Metabolyz vs Open Water Rx →
  6. 06C

    LifespanningRx

    Ranked #374

    LifespanningRx is a longevity/peptide-therapy telehealth brand (NAD+, Sermorelin, glutathione, B12) rather than a dedicated GLP-1 weight-loss provider.

    Sema
    Not disclosed
    Tirz
    Not disclosed
    Coverage
    All 50 states
    Brand
    Yes
    Visit LifespanningRx LifespanningRx vs Open Water Rx →
  7. 07C

    Heros Health

    Ranked #373

    Heros Health is a direct-to-consumer telehealth platform offering compounded semaglutide and tirzepatide for weight loss on a flat program price — $149 the first month.

    Sema
    $199/mo (compounded)
    Tirz
    $199/mo (compounded)
    Coverage
    Multi-state
    Brand
    Compounded
    Visit Heros Health Heros Health vs Open Water Rx →
  8. 08C

    Freya Meds

    Ranked #372

    Freya Meds is a GLP-1-only telehealth brand bundling medication with unlimited doctor consultations, monthly group calls, and a dietitian consultation.

    Sema
    $297/mo (0.20 mg dose, compounded)
    Tirz
    $390/mo (0.20 mg dose, compounded)
    Coverage
    Multi-state
    Brand
    Yes
    Visit Freya Meds Freya Meds vs Open Water Rx →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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