Rx.com review
Prints "No automatic renewals" on the plan card and names the pharmacy that dispenses, with a street address — then advertises another drug's prepay rate.
- Semaglutide
- $175/mo month-to-month; $165 on three months and $146 on six
- Tirzepatide
- $285/mo month-to-month; $265 on three months and $259 on six
- Coverage
- 49 states on its plan page; its own banner says all 50
- Brand-name
- Compounded only
Semaglutide · modeled / year
$2,100
Tirzepatide · modeled / year
$3,420
Pricing verified September 2026
The Index scorecard
Rx.com scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- "No automatic renewals" is printed under the plan card itself rather than buried in the terms
- Names Manifest Pharmacy in Greer, South Carolina with a full street address, and MD Integrations as the provider network, on the same page as the price
- One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included
- A provider who declines to prescribe does not charge for medication
The tradeoffs
- The advertised "$146/mo FOR LIFE" is a six-month prepay on semaglutide; month-to-month tirzepatide is $285
- The plan page says 49 states served while the banner on the same site says all 50
- Injection only — no oral route and no brand-name lane
- LegitScript is claimed in the footer and we did not verify who holds the id
The bottom line
Best for: Someone who will judge it by the plan card rather than the banner, and who values no auto-renewal and a named pharmacy over the lowest sticker. Prints "No automatic renewals" on the plan card and names the pharmacy that dispenses, with a street address — then advertises another drug's prepay rate.
Ranked #45 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Rx.com.
- #40Welling Health— Welling Health is a clinician-led metabolic telehealth platform charging a flat $190/month for compounded semaglutide and $275/month for compounded tirzepatide, all doses, with no setup or consultation fees.78/100
- #41FMmeds— FMmeds is a compounded-GLP-1 telehealth membership selling semaglutide from $95/mo and tirzepatide from $145/mo, both co-formulated with Vitamin B12 and dispensed by Manifest Pharmacy.78/100
- #42Renlo Health— A price lock, a named prescriber and a named pharmacy — and a headline that is the actual monthly rate rather than a prepay divided down.78/100
- #43Enhance MD— The clearest tiered price ladder in this ranking — separate published lines for semaglutide, tirzepatide, a microdose tier and a sema+tirz combo — with lab work built into every tier.75/100
- #44PreventiveMD— PreventiveMD is a physician-guided telehealth platform for GLP-1 weight loss and peptide therapy, offering compounded semaglutide from $83/mo all-in and compounded tirzepatide from $97/mo all-in.77/100
- #46HealthRX— Publishes its entire term ladder as machine-readable data — and advertises the twelve-month rung, so the price on the tin is roughly half the price you pay month to month.74/100
The 23 programs nearest this one
- #47 Pallas Health74
- #48 EverSlim76
- #49 Maves76
- #50 NiceRx76
- #51 Vytora Health76
- #52 Rylo Health75
- #53 Synergy Rx72
- #54 Peter MD72
- #55 EdgeRx74
- #56 Amble74
- #57 Aspen74
- #58 DoctorAdam74
- #59 Jyra Health74
- #60 Nalena74
- #61 NextMeds74
- #62 Science & Co74
- #63 Gala Health71
- #64 Direct Meds71
- #65 He & She MD71
- #66 SkinnyRx71
- #67 Amazon One Medical73
- #68 MyFastRx73
- #69 Navio MD73
Pricing, states and verification reflect Rx.com's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Rx.com's site. Not medical advice; see our disclosure.