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Ranked #339 · Grade C

MediRX review

MediRx is a weight-loss telehealth storefront that white-labels OpenLoop Health's clinician network for actual prescribing and pharmacy fulfillment.

Visit MediRX Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.
Semaglutide
$149/mo (starting dose, compounded)
Tirzepatide
$199/mo (starting dose, compounded)
Coverage
Coverage not published
Brand-name
Compounded only

Semaglutide · modeled / year

$1,788

Tirzepatide · modeled / year

$2,388

Pricing verified August 2026

The Index scorecard

MediRX scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month58/100
Price Transparency78/100
Nationwide Access24/100
Formulation Options66/100
Clinical Oversight74/100
Contract Flexibility20/100

Where the value is

  • Publishes specific dollar pricing for both injection and oral-tablet forms of both drugs
  • Rare self-disclosed distinction between promotional ($149) and standard ($179) semaglutide pricing
  • LegitScript badge displayed on the page
  • Genuine prescribing via OpenLoop Health's licensed clinician network, not a pure pass-through pharmacy

The tradeoffs

  • MediRx itself has no named medical director -- all clinical care is outsourced to OpenLoop Health's network
  • Tirzepatide's wide $199-$399 range makes the true likely monthly cost at a therapeutic dose unclear
  • No specific compounding pharmacy is named beyond OpenLoop's unnamed 'partnered' pharmacies
  • No states-served list found in accessible page content

The bottom line

Best for: Shoppers who want transparent published pricing and don't mind that prescribing is handled by a third-party clinician network (OpenLoop) rather than an in-house medical team. MediRx is a weight-loss telehealth storefront that white-labels OpenLoop Health's clinician network for actual prescribing and pharmacy fulfillment.

Ranked #339 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.

Compare with other providers

All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to MediRX.

The 24 programs nearest this one

Pricing, states and verification reflect MediRX's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on MediRX's site. Not medical advice; see our disclosure.

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