PrescrYbe Review: Price, Pros & Cons
PrescrYbe lists compounded semaglutide at $249 and tirzepatide at $339 per four-week cycle before you start, with oral semaglutide at $279 and microdose plans at $179; a four-week cycle means 13 charges a year.
- Semaglutide
- $249Every 4 weeks (compounded injection; oral $279, microdose $179)
- Tirzepatide
- $339Every 4 weeks (compounded injection; microdose $179)
- Coverage
- All 50 states + DC
- Brand-name
- Compounded only
Semaglutide · modeled / year
$3,237
13 charges a year: billed every four weeks
Tirzepatide · modeled / year
$4,407
13 charges a year: billed every four weeks
The Index scorecard
PrescrYbe scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Five GLP-1 plans are priced on the weight-loss page before any questionnaire: semaglutide injection $249, tirzepatide injection $339, oral semaglutide $279, and microdose semaglutide or tirzepatide at $179
- Offers an oral semaglutide formulation as well as weekly injections
- Names its clinical partner, OpenLoop Health, and says plans are evaluated by board-certified clinicians, with follow-ups to adjust dosing and manage side effects
- You can cancel at any time from your account or by email, and a full refund applies if you cancel within 72 hours before any service is delivered or if a provider finds you ineligible
The tradeoffs
- Every price is charged per four weeks, not per month, so a year is 13 charges: $3,237 for semaglutide injections rather than 12 × $249
- Cancellations must reach support at least 72 hours before the next billing date, and a cycle that has already been charged is not refunded
- The dispensing pharmacy is not named; the site says only that a licensed pharmacy partner fills prescriptions
- The weight-loss FAQ describes a different kind of program (insurance help, prior authorizations, weekly group coaching, lab testing) than the cash-pay medication plans priced above it, so confirm what your plan includes before paying
- The site claims all 50 states and D.C. but adds that some services may not be available everywhere, and it publishes no state-by-state list
- Compounded semaglutide and tirzepatide are not FDA-approved products
The bottom line
Best for: Shoppers who want an injection, an oral tablet or a microdose plan priced up front on one page, and who budget by the four-week cycle rather than the month. PrescrYbe lists compounded semaglutide at $249 and tirzepatide at $339 per four-week cycle before you start, with oral semaglutide at $279 and microdose plans at $179; a four-week cycle means 13 charges a year.
For comparison, read our review of CoreAge Rx, one of our partners. Partners are listed first on our leaderboard; every provider is scored on the same six factors.
Other programs to compare with PrescrYbe
These are partners: we may earn a commission if you sign up, at no cost to you.
CollectivePartner
Semaglutide from $59/mo · tirzepatide from $69/mo
Collective sells compounded semaglutide at $59 and tirzepatide at $69 a month, both genuinely medication prices, on top of a $199 annual membership that is required, auto-renewing and not refundable.
LttlPartner
Semaglutide from $99/mo · tirzepatide from $149/mo
Lttl charges $99 every four weeks for compounded semaglutide and $149 for tirzepatide on a cancel-anytime auto-refill, with small discounts for longer supplies.
RNK HealthPartner
Semaglutide from $197/mo · tirzepatide from $297/mo
Compounded semaglutide from $197 a month and tirzepatide from $297, with the doctor visit, medication, supplies and shipping in one monthly price you can cancel.
Compare with other providers
The providers whose Cost-Efficiency Index scores sit closest to PrescrYbe's. See the alternatives to PrescrYbe.
- Pallas Health— Prices both molecules openly and bills them in 12-week blocks — $597 and $897 up front, with no monthly option to fall back on.74/100
- Science & Co— Declares in its own footer that it is not a compounding facility, and explains its own asterisk in its own FAQ — two disclosures most of this market never makes.74/100
- Found Youth— Found Youth sells compounded semaglutide at $249 and tirzepatide at $329 for a one-month term, with cheaper three- and six-month terms paid up front, and names the Miami pharmacy that fills every order.74/100
- Amazon One Medical— Amazon One Medical's GLP-1 program prescribes brand-name drugs only, never compounded ones, and charges a separate ~$39 initial care fee on top of the medication.73/100
- MyFastRx— MyFastRx is a cash-pay compounded-GLP-1 platform with a full published price ladder: a $139/mo semaglutide and $199/mo tirzepatide standing month-to-month rate, a discounted first month with a promo code.73/100
- Navio MD— NavioMD is a 48-state telehealth platform selling compounded tirzepatide from $189/mo plus brand-name Ozempic, Zepbound, and Mounjaro at near-retail 'as low as' prices.73/100
Pricing, states and verification reflect PrescrYbe's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on PrescrYbe's site. Not medical advice; see our disclosure.