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Provider review

Nucore Health Review: Price, Pros & Cons

By The WeighLab Bench, Tools & Data Desk

Nucore Health offers compounded semaglutide from $179 a month, tirzepatide from $269 and an oral semaglutide option from $209, with no membership fee.

In this review

Compounded drugs are not FDA-approved. Treatment requires a clinician's assessment. Understand compounded GLP-1 treatment.

Check Nucore Health prices Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.

Prices at a glance

Semaglutide
$179/moAs low as; dose and plan terms need confirmation, compounded
Tirzepatide
$269/moAs low as; dose and plan terms need confirmation, compounded
Coverage
All 50 states
Brand-name
Not confirmed

Semaglutide · estimated annual cost

$2,148

Tirzepatide · estimated annual cost

$3,228

Who Nucore Health may suit

Shoppers comparing injectable and oral GLP-1 options who will confirm the price at their prescribed dose.

Where the value is

  • Publishes separate monthly starting figures for semaglutide, tirzepatide and an oral semaglutide option
  • LegitScript certification badge displayed
  • Claims nationwide coverage across all 50 states
  • FSA/HSA eligible, no insurance required

The tradeoffs

  • Starting figures do not show a complete dose or plan-length price ladder; ask what your ongoing prescription costs
  • Fullscript powers the supplement store; the compounding pharmacy filling GLP-1 prescriptions is not named
  • No medical director named
  • 'Any dose' flat pricing isn't spelled out at higher doses, so ask what a maintenance dose costs

What Nucore charges

Nucore sells compounded semaglutide and compounded tirzepatide injections, plus an oral option, each at a monthly price with no membership fee. Semaglutide starts at $179 a month, tirzepatide at $269 and oral semaglutide at $209. Each is an "as low as" figure, so the amount at your dose or plan may differ. Tirzepatide and the oral form have their own monthly prices, and a separate microdosing program starts lower. Ask which plan length and dose your quote covers.

Nucore doesn't take insurance, and its plans are HSA and FSA eligible. Most products can be set to auto-renew every 30 or 90 days. If you buy a bundled multi-month plan, know that a refund on it is recalculated at standard, non-discounted prices.

Considering Nucore Health?

Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.

Who prescribes and who fills it

Nucore runs the platform. Its terms name OpenLoop Health as a vendor that helps run its telehealth services, alongside independent licensed providers, pharmacies and labs. Nucore doesn't name a medical director or the compounding pharmacy that fills GLP-1 prescriptions. Fullscript, which appears on Nucore's site, powers its supplement store, not its prescriptions. Nucore says its compounds use pharmaceutical-grade ingredients in base form rather than salt form, and that the pharmacy runs third-party tests for potency, sterility and toxins.

You pick a treatment, fill out a medical intake, and a licensed provider decides whether to prescribe. Nucore says it serves all 50 states. Approved orders usually ship within one to two business days and arrive in two to three, and cold-packed items ship Monday through Thursday only. Follow-ups are monthly until your dose is steady, then every three months.

Canceling and refunds

You cancel by email at least 72 hours before your next billing date. A later request may still be billed for the coming cycle, with the cancellation taking effect the cycle after. You keep access through the end of the period you've paid for.

Refunds are narrow. You can get the current cycle back only if your medication hasn't been ordered, processed, dispensed or shipped. For new patients, ordering usually happens as soon as you submit the intake, or right after a live visit if your state needs one, so the window closes fast. Refunds cover only the current cycle and are reviewed case by case. On bundled plans, Nucore prorates any approved refund using the shipments you've received and its standard prices. If a provider finds you ineligible before medication is ordered, you can get a full refund for that cycle.

Before you sign up

  • Ask what your monthly price will be at a maintenance dose, not just at the start.
  • Check the renewal interval, 30 or 90 days, at checkout.
  • Compounded semaglutide and tirzepatide are not FDA-approved.

The Index scorecard

Nucore Health scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month65/100
Price Transparency78/100
Nationwide Access86/100
Formulation Options77/100
Clinical Oversight82/100
Contract Flexibility55/100

The bottom line

Nucore Health offers compounded semaglutide from $179 a month, tirzepatide from $269 and an oral semaglutide option from $209, with no membership fee.

Compare the total cost of other GLP-1 programs and alternatives to Nucore Health before deciding. A clinician should help you choose the right treatment.

Other programs to compare with Nucore Health

These are partners: we may earn a commission if you sign up, at no cost to you.

  • EdenPartner

    Semaglutide modeled $99/mo · Tirzepatide modeled $129/mo

    Eden charges $99 a month for compounded semaglutide and $129 for compounded tirzepatide, the same at every dose, with the visit, medication and shipping included.

  • FoundPartner

    Semaglutide modeled $215.58/mo · Tirzepatide modeled $313.08/mo

    Found bundles compounded semaglutide or tirzepatide into a care plan you can pay for with insurance or cash; month to month, semaglutide is $199 insured or $289 cash.

  • ShedRx (Shed)Partner

    Semaglutide modeled $199/mo · Tirzepatide modeled $299/mo

    Shed sells its GLP-1s as an injection, drops, lozenges or a daily pill, with brand-name Zepbound too; month to month, semaglutide is $199 and tirzepatide $299.

Compare with other providers

The providers whose Cost-Efficiency Index scores sit closest to Nucore Health's. See the alternatives to Nucore Health.

Explore more provider reviews

Pricing, states and verification reflect Nucore Health's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Nucore Health's site. Not medical advice; see our disclosure.

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