Synergy Rx Review: Price, Pros & Cons
Synergy Rx lists compounded injections, dissolving tablets and brand-name GLP-1s at published starting prices, with provider care and shipping.
In this review
Compounded drugs are not FDA-approved. Treatment requires a clinician's assessment. Understand compounded GLP-1 treatment.
Prices at a glance
- Semaglutide
- $199Starting price (compounded injection; billing cycle and dose not stated)
- Tirzepatide
- $349Starting price (compounded injection; billing cycle and dose not stated)
- Coverage
- All 50 states claimed in FAQ; subject to provider availability
- Brand-name
- Yes
Semaglutide · estimated annual cost
$2,388
Tirzepatide · estimated annual cost
$4,188
Who Synergy Rx may suit
Readers comparing injection, dissolving-tablet and brand-name routes who will confirm the plan total and billing schedule.
Where the value is
- Offers compounded injections, compounded oral dissolving tablets and brand-name Wegovy, Mounjaro and Ozempic
- Lists starting prices before consultation
- FAQ says all 50 states, subject to state rules and licensed-provider availability
- Names four pharmacy partners in its FAQ
The tradeoffs
- Starting figures do not specify the billing cycle or dose; confirm the complete plan total
- Oral semaglutide starts at $299 and oral tirzepatide at $399, above the injection floors
- State availability is conditional; confirm that a licensed provider can treat you
- Get cancellation and refund terms in writing before paying
What Synergy Rx lists
Synergy Rx publishes "starting at" prices for each weight-loss medication it offers:
| Medication | Starting at |
|---|---|
| Compounded semaglutide injection | $199/mo |
| Compounded tirzepatide injection | $349/mo |
| Compounded semaglutide dissolving tablet | $299/mo |
| Compounded tirzepatide dissolving tablet | $399/mo |
| Wegovy | $947/mo |
| Mounjaro | $947/mo |
| Ozempic | $499/mo |
Those are floors, not quotes. Synergy says the final price depends on your treatment plan and the medication you're prescribed, and that you'll see full pricing after your consultation. It doesn't say whether the starting price is month to month or tied to a longer plan, or whether it rises with the dose. Ask both before you pay.
New patients get a $100 welcome credit at checkout with no code needed. Shipping is free, and FSA and HSA cards are accepted. Synergy notes that most insurance plans don't cover GLP-1s for weight loss through telemedicine, and its providers don't bill insurance or Medicare.
Considering Synergy Rx?
Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.
How it works
You fill out a questionnaire online, then a licensed provider in your state reviews it and builds a treatment plan. Before each refill, your provider checks your progress and adjusts the dose if needed, with check-ins monthly or quarterly. Medication ships discreetly to your door.
Synergy runs on a patient management platform called CareGLP. The doctors and nurse practitioners are independent professionals working with affiliated medical groups, and CareGLP isn't itself a medical practice or a pharmacy. Synergy's FAQ names four compounding pharmacies it works with. Ask which one will fill your prescription.
Support
Synergy says its plans include unlimited appointments, unlimited messaging and round-the-clock access to its clinical team. If you have side effects or want to stop, you contact your provider through the patient portal, and they can guide you through tapering or switching medications.
Things to check before you sign up
- Your state. The FAQ says Synergy's services reach all 50 states, subject to each state's rules. Its terms say the service is only available in certain states and tell you to email customer service for the current list. Confirm yours first.
- Refunds and canceling. Synergy's about page mentions a money-back guarantee, but its terms don't spell out how refunds or cancellations work, and they say consultation fees aren't refundable. Get the rules in writing.
- Dose pricing. Ask whether the price changes as your dose increases.
- Eligibility. Synergy follows the usual guideline: a BMI of 30 or higher, or 27 and up with a weight-related condition such as high blood pressure.
The Index scorecard
Synergy Rx scored on our six Cost-Efficiency Index factors. See the methodology.
The bottom line
Synergy Rx lists compounded injections, dissolving tablets and brand-name GLP-1s at published starting prices, with provider care and shipping.
Compare the total cost of other GLP-1 programs and alternatives to Synergy Rx before deciding. A clinician should help you choose the right treatment.
Other programs to compare with Synergy Rx
These are partners: we may earn a commission if you sign up, at no cost to you.
OakPartner
Semaglutide modeled $250/mo · Tirzepatide modeled $300/mo
Oak's order form charges $250 a month for compounded semaglutide and $300 for tirzepatide at every dose, with no subscription and brand-name pens on the same menu, while its marketing pages advertise figures from $89 to $190 that the form does not offer.
EmbodyPartner
Semaglutide modeled $79/mo · Tirzepatide modeled $129/mo
Embody sells compounded semaglutide from $79 a month and tirzepatide from $129, marked as sale prices, with prescribers from the OpenLoop Health network.
Enhance MDPartner
Semaglutide modeled $212/mo · Tirzepatide modeled $280/mo
Enhance MD charges $212 a month for compounded semaglutide and $280 for tirzepatide at every dose, with lab work every six months included; the first month is $100 less.
Compare with other providers
The providers whose Cost-Efficiency Index scores sit closest to Synergy Rx's. See the alternatives to Synergy Rx.
- KERNX Health— KERNX Health charges one flat monthly price at every dose — $209 for compounded semaglutide, $299 for compounded tirzepatide — with no consultation or membership fee, and names its prescribing clinicians individually.79/100
- Somira Health— Somira Health offers compounded semaglutide at $139.99 a month and tirzepatide at $159.99 a month, or three-month subscriptions billed as $299.99 and $399.99.79/100
- Mondae— Mondae charges $87 for compounded semaglutide and $126 for tirzepatide every 28 days, with the medication, the supplies, unlimited clinician messaging and shipping inside the figure and no consultation or membership fee.79/100
- Trimi Health— Trimi charges $175 a month for compounded semaglutide and $235 for tirzepatide month to month; the $99 and $125 it advertises are the prices on a prepaid year.78/100
- Welling Health— Welling Health sells a yearly lab and body-scan membership; its prescription track, which would include GLP-1 medication, isn't open yet.78/100
- Amble— Amble is a managed-services telehealth platform (by its own terms, not itself a medical facility or pharmacy) selling compounded semaglutide and tirzepatide at IDENTICAL prices on a commitment-length pricing table: $179/mo with no commitment.78/100
Pricing, states and verification reflect Synergy Rx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Synergy Rx's site. Not medical advice; see our disclosure.