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Best-value alternatives

Alternatives to Synergy Rx

Synergy Rx scores 72/100 on our Cost-Efficiency Index (ranked #53 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.

Read the Synergy Rx review →CoreAge Rx vs Synergy Rx →
  1. Our #1 pick
    01A

    CoreAge Rx

    Ranked #1

    Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded
    Visit CoreAge Rx CoreAge Rx vs Synergy Rx →
  2. 02C

    Rylo Health

    Ranked #52

    Rylo Health is a compounded GLP-1/NAD+/peptide telehealth platform operating in all 50 states through Lone Star Virtual Health PLLC and dispensing via VialsRX in Houston, TX.

    Sema
    $149/mo (all doses, promotional rate, compounded)
    Tirz
    $249/mo (all doses, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
    Visit Rylo Health Rylo Health vs Synergy Rx →
  3. 03C

    Vytora Health

    Ranked #51

    Vytora Health (Wasef Health, PC) is a 50-state-plus-DC telehealth platform selling flat-rate compounded semaglutide and tirzepatide alongside retail-priced brand-name Mounjaro and Zepbound ($1,399/mo each).

    Sema
    $179/mo (all doses, compounded)
    Tirz
    $199/mo (all doses, 3-month plan, compounded)
    Coverage
    All 50 states
    Brand
    Yes
    Visit Vytora Health Vytora Health vs Synergy Rx →
  4. 04C

    NiceRx

    Ranked #50

    NiceRx is a compounded GLP-1 telehealth platform charging $199/mo for semaglutide and $299/mo for tirzepatide on an ongoing month-to-month basis (first month discounted to $99 and $199 respectively).

    Sema
    $199/mo (all doses, compounded)
    Tirz
    $299/mo (all doses, compounded)
    Coverage
    46 states
    Brand
    Compounded
    Visit NiceRx NiceRx vs Synergy Rx →
  5. 05C

    Maves

    Ranked #49

    Maves (operated by parent company Homera Health) is a men's-health/performance-framed telehealth platform offering compounded semaglutide and tirzepatide plus sermorelin.

    Sema
    $89/mo (starting dose, compounded)
    Tirz
    Not disclosed
    Coverage
    All 50 states
    Brand
    Yes
    Visit Maves Maves vs Synergy Rx →
  6. 06C

    EverSlim

    Ranked #48

    EverSlim is a US telehealth program selling doctor-prescribed compounded GLP-1 medication delivered to the door, with compounded semaglutide from $117 a month and compounded tirzepatide from $140 a month.

    Sema
    $117/mo (compounded)
    Tirz
    $140/mo (compounded)
    Coverage
    All 50 states
    Brand
    Compounded
    Visit EverSlim EverSlim vs Synergy Rx →
  7. 07C

    Pallas Health

    Ranked #47

    Prices both molecules openly and bills them in 12-week blocks — $597 and $897 up front, with no monthly option to fall back on.

    Sema
    $199/mo average — Pallas's own figure for $597 billed every 12 weeks, its only cadence; $139 covers the first 4 weeks
    Tirz
    $299/mo average — Pallas's own figure for $897 billed every 12 weeks, its only cadence; $179 covers the first 4 weeks
    Coverage
    Most states
    Brand
    Compounded
    Visit Pallas Health Pallas Health vs Synergy Rx →
  8. 08C

    HealthRX

    Ranked #46

    Publishes its entire term ladder as machine-readable data — and advertises the twelve-month rung, so the price on the tin is roughly half the price you pay month to month.

    Sema
    $190/mo (all doses, compounded)
    Tirz
    $239/mo (all doses, compounded)
    Coverage
    All 50 states
    Brand
    Compounded
    Visit HealthRX HealthRX vs Synergy Rx →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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