Best-value alternatives
Alternatives to Fifty 410
Fifty 410 scores 59/100 on our Cost-Efficiency Index (ranked #263 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.
- Our #1 pick01A94/ 100Index
CoreAge Rx
Ranked #1Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 02C57/ 100Index
Collective
Ranked #262Collective sells compounded semaglutide at $59 and tirzepatide at $69 a month, both genuinely medication prices, on top of a $199 annual membership that is required, auto-renewing and not refundable.
- Sema
- $59/mo for the medication, plus a required $199/year membership billed separately
- Tirz
- $69/mo for the medication, plus the same required $199/year membership
- Coverage
- Multi-state
- Brand
- Compounded
- 03C60/ 100Index
VevaRX
Ranked #261VevaRX sells compounded semaglutide at $189 a month and tirzepatide only as a $467 quarterly plan with a three-month minimum, on a site that prints at least eight mutually contradictory prices for its own products.
- Sema
- $189/month month-to-month (the same page also prints $167/month and a $467 three-month total)
- Tirz
- $155.67/mo equivalent — VevaRX bills $467 every three months on a three-month minimum and publishes no monthly plan
- Coverage
- 36 states
- Brand
- Compounded
- 04C60/ 100Index
YourHealthRx
Ranked #260YourHealthRx is a scientist-founded peptide and GLP-1 telehealth platform available in all 50 states and DC via a multi-state (IMLC) clinician network.
- Sema
- $170/mo (compounded)
- Tirz
- $210/mo (compounded)
- Coverage
- All 50 states
- Brand
- Compounded
- 05C60/ 100Index
VitaFusions IV
Ranked #259VitaFusions IV is a Dallas, TX-based IV-therapy and medical-weight-loss provider that does genuinely sell compounded semaglutide ($149/mo) and tirzepatide ($189/mo) at a flat, dose-independent monthly rate with no memberships or contracts.
- Sema
- $149/mo (all doses, contract term, plus a separate fee, compounded)
- Tirz
- $189/mo (all doses, contract term, compounded)
- Coverage
- Multi-state
- Brand
- Compounded
- 06C60/ 100Index
Oxford's Medical Weight Loss (The Calibrate Clinic)
Ranked #258The Calibrate Clinic is a Lafayette, Louisiana-based telehealth weight-loss provider offering phone-only consultations and nationwide shipping for compounded GLP-1 and GLP-1+GIP treatments.
- Sema
- $145/mo (plus a separate fee, compounded)
- Tirz
- $199/mo (compounded)
- Coverage
- 2 states
- Brand
- Compounded
- 07C60/ 100Index
StackMD
Ranked #257StackMD (stackmdhealth.com) is a telehealth weight-loss and longevity platform advertising both compounded semaglutide and tirzepatide at an identical 'starting at $99/month' headline price with no dose tiers shown -- likely a lowest-dose teaser rather than a representative cost.
- Sema
- Not disclosed
- Tirz
- Not disclosed
- Coverage
- All 50 states
- Brand
- Compounded
- 08C60/ 100Index
RxPepsDirect
Ranked #256RxPepsDirect (Peptide RX LLC) is a per-vial compounded GLP-1 telehealth platform whose advertised vial prices are not the whole cost: a flat medical visit charge and flat overnight delivery are added to every order.
- Sema
- $79/mo (starting dose, visit fee and shipping included, compounded)
- Tirz
- $99/mo (starting dose, visit fee and shipping included, compounded)
- Coverage
- 28 states
- Brand
- Compounded
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.