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Provider review

Blis MD Review: Price, Pros & Cons

By The WeighLab Bench, Tools & Data Desk

Blis MD sells compounded semaglutide and tirzepatide by vial strength, starting at $109 and $159 for a one-month supply. Higher doses cost more; oral semaglutide and prepaid starter kits are also listed.

In this review

Compounded drugs are not FDA-approved. Treatment requires a clinician's assessment. Understand compounded GLP-1 treatment.

Check Blis MD prices Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.

Prices at a glance

Semaglutide
$109/mo0.25 mg weekly starting dose, compounded; higher doses $129–$189
Tirzepatide
$159/mo2.5 mg weekly starting dose, compounded; higher doses $199–$270
Coverage
29 states
Brand-name
Not confirmed

Semaglutide · estimated annual cost

$1,308

Tirzepatide · estimated annual cost

$1,908

Who Blis MD may suit

Patients in its twenty-nine covered states who want one-time vial purchases and will budget for the higher prescribed strength.

Where the value is

  • Publishes a dose-based price ladder for both injections
  • No automatic refill or subscription required for one-time purchases
  • Free consultation, shipping and provider messaging advertised
  • Lists twenty-nine covered states in its FAQ
  • Oral semaglutide with pyridoxine is listed from $159 per thirty tablets

The tradeoffs

  • The $109 and $159 prices are starting doses, not flat prices at every strength
  • The dispensing pharmacy and medical director are not named
  • Prescription return and refund eligibility needs confirmation before an order
  • Compounded oral tablets are not FDA-approved semaglutide products

Blis MD prices by the vial

Blis MD sells compounded semaglutide from $109 and compounded tirzepatide from $159, but those are the starting-dose prices. Each order is one vial, a one-month supply, and the price goes up with the strength of the vial as your weekly dose rises.

Weekly doseSemaglutide vial
0.25 mg$109
0.5 mg$129
1 mg$149
1.5 mg$169
2.5 mg$189

Tirzepatide follows the same pattern, starting at $159 for a vial covering 2.5 mg a week and climbing in steps to $270 for a vial covering 15 mg a week.

There's also a three-month kit called the Blis Reset, which bundles three vial strengths with syringes and alcohol pads at a lower total than buying them one at a time. There are no doctor's fees or subscription fees, and shipping is free. Compounded semaglutide with pyridoxine is also sold as thirty oral tablets, from $159 to $349 depending on strength. Those tablets are not FDA-approved oral semaglutide products.

Considering Blis MD?

Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.

Buying without a subscription

Each product page sells a one-time purchase, not an auto-refill plan. Once your medical forms are approved, Blis MD says you can reorder whenever you need to, following your dosing plan. That means nothing renews by itself, but it also means you have to remember to order the next vial in time.

You can start two ways. Book a free virtual consultation first, or, if you already know what you want, order from the shop and complete a short medical intake of about five minutes. A licensed clinician reviews it, and Blis MD says most patients are approved and shipped within 24 to 48 hours. Medication comes from a U.S. 503A compounding pharmacy, which it doesn't name, in temperature-controlled packaging.

Where it treats and who's behind it

Blis MD is a Florida-based virtual clinic. Its founder and medical director is a primary care physician with more than 17 years of practice, though the site doesn't give her name. It currently serves 29 states: Arizona, California, Colorado, Connecticut, Florida, Georgia, Illinois, Indiana, Kentucky, Massachusetts, Maryland, Michigan, Missouri, North Carolina, North Dakota, Nevada, New York, Ohio, Oklahoma, Oregon, Pennsylvania, South Carolina, South Dakota, Tennessee, Texas, Utah, Virginia, Washington and Wyoming.

After you're set up, you can message your practitioner in your account, and Blis MD says replies come within 24 hours. Its tirzepatide plan lists check-ins every two weeks.

Payment and refunds

Blis MD doesn't take insurance of any kind, but HSA and FSA cards work. It doesn't publish a written refund policy. Its FAQ says that if you're not satisfied, support will adjust your plan, suggest alternatives, or walk you through refund or exchange options depending on the product. Ask what applies to a compounded vial before you order, since medication usually can't be returned once it ships. Blis MD also sells testosterone, sermorelin, NAD+ and other peptides from the same shop.

The Index scorecard

Blis MD scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month82/100
Price Transparency78/100
Nationwide Access52/100
Formulation Options77/100
Clinical Oversight79/100
Contract Flexibility55/100

The bottom line

Blis MD sells compounded semaglutide and tirzepatide by vial strength, starting at $109 and $159 for a one-month supply. Higher doses cost more; oral semaglutide and prepaid starter kits are also listed.

Compare the total cost of other GLP-1 programs and alternatives to Blis MD before deciding. A clinician should help you choose the right treatment.

Other programs to compare with Blis MD

These are partners: we may earn a commission if you sign up, at no cost to you.

  • bmiMDPartner

    Semaglutide modeled $159/mo · Tirzepatide modeled $249/mo

    bmiMD charges $159 a month for compounded semaglutide and $249 for tirzepatide month to month, the same at every dose, with lower prices on three-, six- and twelve-month plans.

  • RxSpan MDPartner

    Semaglutide modeled $249/mo · Tirzepatide modeled $329/mo

    RxSpan MD puts injections, oral capsules and three brand-name drugs on one account, with every price and plan length published; one month of the semaglutide injection is $249.

  • Sprout HealthPartner

    Semaglutide modeled $161.42/mo · Tirzepatide modeled $215.58/mo

    Sprout charges $149 every four weeks for compounded semaglutide and $199 for tirzepatide, or $99 and $149 a month if you prepay a full year.

Compare with other providers

The providers whose Cost-Efficiency Index scores sit closest to Blis MD's. See the alternatives to Blis MD.

Explore more provider reviews

Pricing, states and verification reflect Blis MD's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Blis MD's site. Not medical advice; see our disclosure.

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