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Provider review

Rex MD Review: Price, Pros & Cons

By The WeighLab Bench, Tools & Data Desk

Rex MD offers a $349 monthly Wegovy pill plan including provider care, alongside separately billed brand-name injection options.

In this review
Check Rex MD prices Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.

Prices at a glance

Semaglutide
$349/moBrand Wegovy pill, all titration doses; provider care included
Tirzepatide
$424/moBrand Zepbound, plus a separate fee
Coverage
All 50 states
Brand-name
Yes

Semaglutide · estimated annual cost

$4,188

Tirzepatide · estimated annual cost

$5,088

Who Rex MD may suit

Patients seeking a Wegovy pill plan with medication and provider care in one monthly price.

Where the value is

  • Wegovy pill plan includes medication and provider care for $349 monthly
  • The pill price is locked across listed titration doses
  • Names Dr. Anthony Puopolo and the Rex MD Affiliated Medical Group
  • Offers brand-name Wegovy and Zepbound prescription routes

The tradeoffs

  • The $349 pill plan differs from the injection route with separate program and manufacturer charges
  • Zepbound pricing depends on the prescribed dose and manufacturer terms
  • The weight program does not accept insurance
  • Confirm the price for your selected formulation before enrolling

How Rex MD's weight program is priced

Rex MD is a men's telehealth brand, owned by LifeMD, best known for ED treatment. Its weight program prescribes brand-name GLP-1s only: Wegovy as a pill or a weekly pen, Zepbound and Saxenda. You pay in two parts, and you need to add them together.

The Rex MD program fee starts at $75 a month. It covers clinician consultations, prescriptions, coaching and any required lab work you haven't had in the last 12 months. The drug is bought separately, from the manufacturer's own cash-pay pharmacy:

MedicationRex MD programDrug, cash payMonthly total
Wegovy pen (any dose)$75$499$574
Zepbound vial (starting)$75$349$424

For Wegovy, your provider sends the prescription to NovoCare, Novo Nordisk's direct-pay pharmacy, and you set up an account there to pay and arrange delivery. Zepbound vials come straight from Eli Lilly's direct program, with the $349 listed as a starting price, so ask what your dose will cost.

The Wegovy pill is sold differently. Rex MD bundles the pill and provider care into one monthly price, and says that price stays the same at every pill dose, from 1.5 mg up to 25 mg. The current pill plan costs $349 a month including provider care; the separate $75 injection-route fee is not added again.

Considering Rex MD?

Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.

Getting a prescription

You fill in an online questionnaire about your goals and health history and upload photos, including a government ID. A Rex MD-affiliated provider reviews it. For many men that's the whole visit, with follow-up questions handled by secure chat or email. Some states and some medications require a phone or video call, which Rex MD arranges.

The affiliated medical group is led by Dr. Anthony Puopolo, its president. Providers are U.S. state-licensed and board-certified. Rex MD serves all 50 states.

You're charged when you finish the onboarding questionnaire. If the provider decides you're not eligible, you get a full refund.

Shipping, renewals and canceling

Weight program medication ships overnight once processed, and Rex MD says the monthly price includes shipping. You can request a dose increase through the patient portal or at a renewal visit.

You can pause or cancel anytime by phone, email or the portal, and there's no long-term contract. Other refunds are handled case by case, and prescriptions can't be returned once dispensed.

Things to know first

  • No insurance. Rex MD's weight program is cash pay only. Its parent company, LifeMD, runs a separate program that does take insurance.
  • Brand-name first. The drug cost is set by the manufacturer, not by Rex MD. Rex MD says its providers can prescribe a compounded version when appropriate, but it doesn't publish a price for one.
  • The $75 is not the full bill. Plan on the combined monthly figure for the drug you choose.
  • HSA and FSA cards are accepted.

The Index scorecard

Rex MD scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month41/100
Price Transparency78/100
Nationwide Access86/100
Formulation Options90/100
Clinical Oversight89/100
Contract Flexibility55/100

The bottom line

Rex MD offers a $349 monthly Wegovy pill plan including provider care, alongside separately billed brand-name injection options.

Compare the total cost of other GLP-1 programs and alternatives to Rex MD before deciding. A clinician should help you choose the right treatment.

Other programs to compare with Rex MD

These are partners: we may earn a commission if you sign up, at no cost to you.

  • MyDrHankPartner

    Semaglutide modeled $249/mo · Tirzepatide modeled $349/mo

    Every price this site advertises is a twelve-month prepay rate — its price display returns the cheapest term by design — so the real month-to-month cost is $249-$349, not the "from $171" on the page.

  • CollectivePartner

    Semaglutide modeled $75.58/mo · Tirzepatide modeled $85.58/mo

    Collective sells compounded semaglutide at $59 and tirzepatide at $69 a month, both genuinely medication prices, on top of a $199 annual membership that is required, auto-renewing and not refundable.

  • LttlPartner

    Semaglutide modeled $107.25/mo · Tirzepatide modeled $161.42/mo

    Lttl charges $99 every four weeks for compounded semaglutide and $149 for tirzepatide on a cancel-anytime auto-refill, with small discounts for longer supplies.

Compare with other providers

The providers whose Cost-Efficiency Index scores sit closest to Rex MD's. See the alternatives to Rex MD.

Explore more provider reviews

Pricing, states and verification reflect Rex MD's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Rex MD's site. Not medical advice; see our disclosure.

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