Rex MD review
Rex MD (a LifeMD brand, historically known for ED telehealth) also runs a real weight-management program, but it is a referral model rather than a compounder: a $75/month Rex MD program fee covers consultation, coaching and labs.
- Semaglutide
- $574/mo (all doses, plus a separate fee, brand-name)
- Tirzepatide
- $424/mo (brand Zepbound, plus a separate fee)
- Coverage
- All 50 states
- Brand-name
- Yes
Semaglutide · modeled / year
$6,888
Tirzepatide · modeled / year
$5,088
Pricing verified August 2026
The Index scorecard
Rex MD scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Genuine FDA-approved brand-name medication (Wegovy, Zepbound, Saxenda) rather than compounded — a different, more regulated tier than most of this list
- Named medical leadership (Dr. Anthony Puopolo, M.D., Rex MD Affiliated Medical Group) and a LegitScript Certified badge
- Backed by publicly known parent LifeMD, with an established telehealth track record
- Program fee ($75/mo) is cancel-anytime with no long-term lock-in disclosed
The tradeoffs
- The headline $75 is NOT the medication cost — Wegovy runs an additional $499/mo (any dose) and Zepbound vials an additional $349/mo, both billed separately by the manufacturer, not Rex MD
- All-in realistic cost is roughly $424-$574/month, far above what a '$75' or even a '$349' headline implies depending on which landing page you see
- Two different Rex MD pages show materially different, hard-to-reconcile pricing structures for what appears to be the same semaglutide product
- Does not accept insurance; no compounded (cheaper) option offered as an alternative
The bottom line
Best for: Cost-first shoppers who want men wanting brand-name Wegovy/Zepbound access through a manufacturer direct-pay bridge, not compounded medication. Rex MD (a LifeMD brand, historically known for ED telehealth) also runs a real weight-management program, but it is a referral model rather than a compounder: a $75/month Rex MD program fee covers consultation, coaching and labs.
Ranked #331 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Rex MD.
- #292Sumbare Wellness— Sumbare Wellness is a telehealth GLP-1 and peptide-therapy provider advertising 'plans from $199/mo,' explicitly contingent on provider review rather than guaranteed at booking.58/100
- #293Transparent Meds— Transparent Meds is an online GLP-1 weight-care service that connects you with licensed medical providers and leads with upfront pricing: compounded weekly injections of semaglutide at an intro $149/month.58/100
- #294Trinity Meds— Trinity Meds (trinitymeds.com) is a LegitScript-certified, 50-state telehealth platform prescribing compounded semaglutide ($99/mo) and tirzepatide ($149/mo) through the OpenLoop Health provider network.58/100
- #295Lttl— Publishes every commitment tier openly — then advertises the twelve-month one, so the price on the tin is 35–40% below what a month-to-month customer pays.55/100
- #29624hrDOC— 24hrDOC is a fast, cash-pay telehealth service selling compounded semaglutide and tirzepatide, both as standard weekly injections and as lower-cost nightly/daily microdose options.57/100
- #297HealthOn— HealthOn is a Shopify-based multi-category telehealth brand (weight loss, longevity, hair, sexual health) selling compounded semaglutide and tirzepatide by monthly or quarterly subscription.57/100
The 24 programs nearest this one
- #332 Vita Bella56
- #333 ZYP Medical56
- #334 Mint Med55
- #335 Premium Health55
- #336 Call-On-Doc55
- #337 CeliaRx55
- #338 Harmony Wellness Clinic55
- #339 MediRX55
- #340 Mint Medical Clinic55
- #341 Nucore Health55
- #342 Optimized Health55
- #343 PeptidesRx55
- #344 Revive Meds55
- #345 Rivas Medical Weight Loss55
- #346 SkyRx55
- #347 TeleDocs36055
- #348 TelePeptide55
- #349 The Aesthetic Concierge55
- #350 The Virtual NP55
- #351 Fierce Health55
- #352 WeightCare54
- #353 BetterMe Rx54
- #354 Gatlan54
- #355 Iron Med RX54
Pricing, states and verification reflect Rex MD's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Rex MD's site. Not medical advice; see our disclosure.