Rex MD Review: Price, Pros & Cons
Rex MD offers a $349 monthly Wegovy pill plan including provider care, alongside separately billed brand-name injection options.
In this review
Prices at a glance
- Semaglutide
- $349/moBrand Wegovy pill, all titration doses; provider care included
- Tirzepatide
- $424/moBrand Zepbound, plus a separate fee
- Coverage
- All 50 states
- Brand-name
- Yes
Semaglutide · estimated annual cost
$4,188
Tirzepatide · estimated annual cost
$5,088
Who Rex MD may suit
Patients seeking a Wegovy pill plan with medication and provider care in one monthly price.
Where the value is
- Wegovy pill plan includes medication and provider care for $349 monthly
- The pill price is locked across listed titration doses
- Names Dr. Anthony Puopolo and the Rex MD Affiliated Medical Group
- Offers brand-name Wegovy and Zepbound prescription routes
The tradeoffs
- The $349 pill plan differs from the injection route with separate program and manufacturer charges
- Zepbound pricing depends on the prescribed dose and manufacturer terms
- The weight program does not accept insurance
- Confirm the price for your selected formulation before enrolling
How Rex MD's weight program is priced
Rex MD is a men's telehealth brand, owned by LifeMD, best known for ED treatment. Its weight program prescribes brand-name GLP-1s only: Wegovy as a pill or a weekly pen, Zepbound and Saxenda. You pay in two parts, and you need to add them together.
The Rex MD program fee starts at $75 a month. It covers clinician consultations, prescriptions, coaching and any required lab work you haven't had in the last 12 months. The drug is bought separately, from the manufacturer's own cash-pay pharmacy:
| Medication | Rex MD program | Drug, cash pay | Monthly total |
|---|---|---|---|
| Wegovy pen (any dose) | $75 | $499 | $574 |
| Zepbound vial (starting) | $75 | $349 | $424 |
For Wegovy, your provider sends the prescription to NovoCare, Novo Nordisk's direct-pay pharmacy, and you set up an account there to pay and arrange delivery. Zepbound vials come straight from Eli Lilly's direct program, with the $349 listed as a starting price, so ask what your dose will cost.
The Wegovy pill is sold differently. Rex MD bundles the pill and provider care into one monthly price, and says that price stays the same at every pill dose, from 1.5 mg up to 25 mg. The current pill plan costs $349 a month including provider care; the separate $75 injection-route fee is not added again.
Considering Rex MD?
Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.
Getting a prescription
You fill in an online questionnaire about your goals and health history and upload photos, including a government ID. A Rex MD-affiliated provider reviews it. For many men that's the whole visit, with follow-up questions handled by secure chat or email. Some states and some medications require a phone or video call, which Rex MD arranges.
The affiliated medical group is led by Dr. Anthony Puopolo, its president. Providers are U.S. state-licensed and board-certified. Rex MD serves all 50 states.
You're charged when you finish the onboarding questionnaire. If the provider decides you're not eligible, you get a full refund.
Shipping, renewals and canceling
Weight program medication ships overnight once processed, and Rex MD says the monthly price includes shipping. You can request a dose increase through the patient portal or at a renewal visit.
You can pause or cancel anytime by phone, email or the portal, and there's no long-term contract. Other refunds are handled case by case, and prescriptions can't be returned once dispensed.
Things to know first
- No insurance. Rex MD's weight program is cash pay only. Its parent company, LifeMD, runs a separate program that does take insurance.
- Brand-name first. The drug cost is set by the manufacturer, not by Rex MD. Rex MD says its providers can prescribe a compounded version when appropriate, but it doesn't publish a price for one.
- The $75 is not the full bill. Plan on the combined monthly figure for the drug you choose.
- HSA and FSA cards are accepted.
The Index scorecard
Rex MD scored on our six Cost-Efficiency Index factors. See the methodology.
The bottom line
Rex MD offers a $349 monthly Wegovy pill plan including provider care, alongside separately billed brand-name injection options.
Compare the total cost of other GLP-1 programs and alternatives to Rex MD before deciding. A clinician should help you choose the right treatment.
Other programs to compare with Rex MD
These are partners: we may earn a commission if you sign up, at no cost to you.
MyDrHankPartner
Semaglutide modeled $249/mo · Tirzepatide modeled $349/mo
Every price this site advertises is a twelve-month prepay rate — its price display returns the cheapest term by design — so the real month-to-month cost is $249-$349, not the "from $171" on the page.
CollectivePartner
Semaglutide modeled $75.58/mo · Tirzepatide modeled $85.58/mo
Collective sells compounded semaglutide at $59 and tirzepatide at $69 a month, both genuinely medication prices, on top of a $199 annual membership that is required, auto-renewing and not refundable.
LttlPartner
Semaglutide modeled $107.25/mo · Tirzepatide modeled $161.42/mo
Lttl charges $99 every four weeks for compounded semaglutide and $149 for tirzepatide on a cancel-anytime auto-refill, with small discounts for longer supplies.
Compare with other providers
The providers whose Cost-Efficiency Index scores sit closest to Rex MD's. See the alternatives to Rex MD.
- Aspire Health— Aspire Health is a Nebraska-founded telehealth practice that prescribes compounded semaglutide and tirzepatide (made with B3) and brand-name Wegovy and Zepbound, with a published dose-by-dose price list and a named PA/NP team.71/100
- Goldspan Health— Goldspan Health sells compounded semaglutide at $229 and tirzepatide at $299 every 28 days, with daily sublingual and low-dose versions of both at lower prices, through a storefront operated by a different company.71/100
- Neuvé Health— Neuvé Health offers standard and microdose GLP-1 injections and oral rapid-dissolve tablets, with medication and clinician review included in its displayed treatment prices.71/100
- altRX— altRx is a compounded GLP-1 telehealth platform run through Usable Health, PC and its affiliated medical practices, offering semaglutide and tirzepatide at a flat 'same price at every dose' rate with no membership fee.70/100
- Zappy Health— Zappy Health (operated by Kare Solutions, LLC, based in La Jolla, CA) is a telehealth platform selling both compounded GLP-1s (semaglutide $249/mo and tirzepatide $349/mo month to month at every dose, less on prepaid plans) and brand pathways to Wegovy and Zepbound.70/100
- Kina— Kina is a menopause-first telehealth platform that also genuinely prescribes GLP-1s for weight management, led by a named clinical lead, Dr. Shannon Arora, PharmD.70/100
Pricing, states and verification reflect Rex MD's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Rex MD's site. Not medical advice; see our disclosure.