Piper review
Now rebranded to Polly — its advertised $135/$199 prices are billed weekly, not monthly, so the real monthly-equivalent cost is roughly $585-$862, not the $135-199 a naive read would assume.
- Semaglutide
- $135/week ($585/mo equiv.)
- Tirzepatide
- $199/week ($862/mo equiv.)
- Coverage
- All 50 states
- Brand-name
- Compounded only
Semaglutide · modeled / year
$7,020
Tirzepatide · modeled / year
$10,344
The Index scorecard
Piper scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Names two specific 503A partner compounding pharmacies (Hallandale Pharmacy, VialsRx) rather than staying anonymous
- Nationwide all-50 access with flat pricing at every dose
- LegitScript-certified seal displayed for the current joinpolly.com domain
The tradeoffs
- The headline $135/$199 prices are billed WEEKLY, not monthly — the real monthly-equivalent cost is roughly $585 (semaglutide) and $862 (tirzepatide)
- Compounded only — no brand-name or oral route
- The brand recently changed names entirely (Piper to Polly), so historical track record under 'Piper' may not transfer cleanly
The bottom line
Best for: Shoppers who understand the pricing is billed weekly and want a flat, dose-independent recurring charge from a named pharmacy. Now rebranded to Polly — its advertised $135/$199 prices are billed weekly, not monthly, so the real monthly-equivalent cost is roughly $585-$862, not the $135-199 a naive read would assume.
Ranked #132 of 529 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 528 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Piper.
- #117Mixx Health & Wellness— Mixx Health & Wellness is a compounded-GLP-1 telehealth clinic under medical director Dr. James David Lawrence III, MD (Georgia), sourcing 'Compounded GLP-1/GIP' from a named pharmacy, Promise Pharmacy (Palm Harbor, FL).68/100
- #118Neuvé Health— Neuvé Health prices twelve GLP-1 products openly — injectable and sublingual, standard and low dose, with a B12 or a glycine base — and then says three different things about whether the medication is inside the monthly figure.68/100
- #119SexyMD— SexyMD prints "from $199" and "from $299" on every page, but those are its 48-week commitment rates: the four-week price is $269 for compounded semaglutide and $369 for tirzepatide.68/100
- #120Oak— Publishes nine different "starting" prices and attaches a term to none of them — the two cheapest appear only beside a $200-off badge its own affiliate page defines as a three-month package, so this ranking files no figure for Oak at all.65/100
- #121MyDrHank— Every price this site advertises is a twelve-month prepay rate — its price display returns the cheapest term by design — so the real month-to-month cost is $249-$349, not the "from $171" on the page.65/100
- #122Alternate Health Club— Alternate Health Club is a compounded-GLP-1 telehealth storefront offering semaglutide at $129/month and tirzepatide at $169/month, both marketed as flat rates that do not rise as the dose is titrated up a real.67/100
The 24 programs nearest this one
- #133 Good Girl Rx66
- #134 TRYM Health66
- #135 DrMedHealth66
- #136 Corsica Health66
- #137 Go Vida Plena66
- #138 Good Life Meds66
- #139 NuvaHealth66
- #140 Rewinding RX66
- #141 TD Tele-Doc Weight Loss66
- #142 TrueMe66
- #143 Tyde Wellness66
- #144 VirtualCare2Go66
- #145 Walgreens Weight Management66
- #146 Primary Clinic (Direct GLP)65
- #147 AbundRX65
- #148 Bon Health65
- #149 Dr. Gillis' Wellness Center65
- #150 DrBrainRx65
- #151 Eloria65
- #152 FeelGood65
- #153 Fitness RX65
- #154 Loop Health65
- #155 Medsol RX65
- #156 PlushCare65
Pricing, states and verification reflect Piper's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Piper's site. Not medical advice; see our disclosure.