Best-value alternatives
Alternatives to Piper
Piper scores 66/100 on our Cost-Efficiency Index (ranked #132 of 529). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.
- Our #1 pick01A94/ 100Index
CoreAge Rx
Ranked #1Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 02C67/ 100Index
Spry
Ranked #131Spry is a weight-loss and anti-aging telehealth brand, founded by Gabriel Mullins, Sara Yoder, and Tyler Bowman.
- Sema
- $199/mo (all doses, compounded)
- Tirz
- $299/mo (all doses, compounded)
- Coverage
- Multi-state
- Brand
- Yes
- 03C67/ 100Index
InstaRX
Ranked #130InstaRx sells compounded semaglutide and tirzepatide at a single flat monthly price regardless of dose — $179/mo and $259/mo respectively — with free expedited shipping.
- Sema
- $179/mo
- Tirz
- $259/mo
- Coverage
- All 50 states
- Brand
- Compounded
- 04C67/ 100Index
Hello Alpha
Ranked #129Hello Alpha is a well-established women's telehealth brand that also genuinely prescribes FDA-approved branded GLP-1s (Wegovy, Ozempic, Mounjaro, Zepbound, and orforglipron/Foundayo) rather than compounded versions.
- Sema
- $79/mo (brand Wegovy, plus a separate fee)
- Tirz
- $79/mo (brand Mounjaro, plus a separate fee)
- Coverage
- Multi-state
- Brand
- Yes
- 05C67/ 100Index
HeliMeds
Ranked #128HeliMeds sells compounded semaglutide and tirzepatide (plus brand Wegovy/Zepbound) through one-time upfront 12-week plans rather than a true subscription — 'you will only be charged once for the selected treatment plan,' per the site.
- Sema
- $99/mo (starting dose, 3-month plan, compounded)
- Tirz
- $149/mo (starting dose, 3-month plan, compounded)
- Coverage
- Multi-state
- Brand
- Yes
- 06C67/ 100Index
HealthHub
Ranked #127HealthHub is a LegitScript-certified telehealth platform (seal 46103909) selling compounded semaglutide and tirzepatide in FOUR formats standard injection, oral dissolving tablet, and a sublingual liquid.
- Sema
- $99/mo (compounded)
- Tirz
- $199/mo (compounded)
- Coverage
- Multi-state
- Brand
- Compounded
- 07C67/ 100Index
FormidableMD
Ranked #126FormidableMD is a Florida-based, physician-led cash-pay telehealth practice selling compounded semaglutide and tirzepatide at transparent, published dose-by-dose prices ($169-$269/mo and $199-$319/mo respectively).
- Sema
- $169/mo (1 mg dose, compounded)
- Tirz
- $199/mo (10 mg dose, plus a separate fee, compounded)
- Coverage
- 1 state
- Brand
- Yes
- 08C67/ 100Index
Factor Health MD
Ranked #125Factor Health MD is a compounded-GLP-1 and general telehealth clinic (LegitScript-certified per its footer badge, based in St. Petersburg, FL) offering semaglutide and tirzepatide.
- Sema
- $99/mo (all doses, annual plan, compounded)
- Tirz
- $149/mo (all doses, annual plan, compounded)
- Coverage
- Multi-state
- Brand
- Compounded
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.