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Ranked #173 · Grade C

AlyveRx review

AlyveRx (Alyve) is a telehealth platform selling compounded semaglutide and tirzepatide in both standard injection and proprietary PermeAct sublingual-drop form, plus brand Ozempic, Wegovy.

Visit AlyveRx Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.
Semaglutide
$183/mo (starting dose, compounded)
Tirzepatide
$283/mo (starting dose, compounded)
Coverage
Coverage not published
Brand-name
Yes

Semaglutide · modeled / year

$2,196

Tirzepatide · modeled / year

$3,396

Pricing verified August 2026

The Index scorecard

AlyveRx scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month66/100
Price Transparency78/100
Nationwide Access24/100
Formulation Options90/100
Clinical Oversight71/100
Contract Flexibility55/100

Where the value is

  • Offers a genuinely needle-free sublingual delivery option (PermeAct) for both semaglutide and tirzepatide, not just injections
  • Also carries brand-name Ozempic, Wegovy, and Mounjaro for patients who want an FDA-approved product
  • All four price points (injection and drops, both drugs) are published upfront on the homepage before intake

The tradeoffs

  • The dataset's previous $249/mo tirzepatide figure is the SUBLINGUAL DROPS price, not the standard injection ($283/mo) — confirm which form a quoted price refers to
  • Sublingual PermeAct absorption relies on the company's own proprietary technology claims and is not FDA-reviewed for weight-loss efficacy
  • No compounding pharmacy or medical director is publicly named
  • No LegitScript certification found, and state availability is not published on the site

The bottom line

Best for: Shoppers who specifically want a needle-free sublingual GLP-1 option alongside standard injections on the same platform. AlyveRx (Alyve) is a telehealth platform selling compounded semaglutide and tirzepatide in both standard injection and proprietary PermeAct sublingual-drop form, plus brand Ozempic, Wegovy.

Ranked #173 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.

Compare with other providers

All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to AlyveRx.

The 23 programs nearest this one

Pricing, states and verification reflect AlyveRx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on AlyveRx's site. Not medical advice; see our disclosure.

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