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Provider review

WeightlessRx Review: Price, Pros & Cons

By The WeighLab Bench, Tools & Data Desk

WeightlessRx is a direct-to-consumer telehealth provider selling compounded semaglutide and tirzepatide with no separate membership or consultation fees layered on top of the drug price.

In this review

Compounded drugs are not FDA-approved. Treatment requires a clinician's assessment. Understand compounded GLP-1 treatment.

Check WeightlessRx prices Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.

Prices at a glance

Semaglutide
$167/moAll doses, $500 total for 3 months prepaid, compounded
Tirzepatide
$233/moAll doses, $700 total for 3 months prepaid, compounded
Coverage
All 50 states
Brand-name
Not confirmed

Semaglutide · estimated annual cost

$2,004

Tirzepatide · estimated annual cost

$2,796

Who WeightlessRx may suit

Shoppers comfortable buying a three-month supply who want medication, clinician messaging, nutrition support, and supplies included.

Where the value is

  • Published three-month totals of $500 for semaglutide and $700 for tirzepatide include every prescribed dose
  • No separate membership or consultation fee; supplies, required labs and shipping included
  • Names VitaScripts Pharmacy and displays a LegitScript certification claim
  • Says it serves all fifty states
  • Cancel by text or email, or pause for up to ninety days

The tradeoffs

  • The displayed monthly figures are averages for a prepaid three-month supply, not a published month-to-month bill
  • The banner offers monthly or three-month plans, but the FAQ says every plan is a three-month supply; confirm your billing term
  • Cancellation needs at least five business days notice to stop the next charge
  • Prescription medication is non-refundable once dispensed
  • No named medical director is disclosed on the marketing page

How WeightlessRx prices its plans

WeightlessRx sells compounded semaglutide and compounded tirzepatide as once-weekly injections. There's no membership fee and no consultation fee on top, and the price is the same at every dose. It covers unlimited clinician messaging, supplies, labs when your clinician requires them, and shipping.

The advertised three-month totals are $500 for semaglutide and $700 for tirzepatide, shown as $167 and $233 per month after rounding. The banner offers a monthly or a three-month plan. The three-month plan carries the lower rate, is billed as one charge for a three-month supply, and comes with a promise that you keep that price for life. The FAQ goes further and says every plan is a three-month supply, so confirm at checkout whether you're paying for one month or three. Tirzepatide costs more than semaglutide, and its plan adds priority shipping in 24 to 48 hours.

Nothing is due when you sign up. Your card is authorized and charged only if a clinician approves you. WeightlessRx doesn't take insurance; it says most members pay with an HSA or FSA card and it'll send a superbill on request.

Considering WeightlessRx?

Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.

Who prescribes and who fills it

WeightlessRx is run by Weightless Rx LLC, a Wyoming company formed in 2025, and says it has no connection to WeightRx. It works with independent U.S.-licensed clinicians and doesn't name a medical director. The intake takes about 90 seconds, a clinician reviews it, and a short video visit is usually available within 24 hours. If you're approved, the first shipment leaves within three to five business days, and the site describes follow-ups every 28 days; confirm whether your prepaid supply ships together or in separate refills.

The compounding pharmacy is VitaScripts Pharmacy. WeightlessRx says each batch passes potency, sterility, pH and endotoxin testing before it ships, and that it serves all 50 states. If you're switching from another GLP-1 program, list your current drug and dose in the intake; your clinician may continue you near that dose rather than starting over.

What comes with the plan

Beyond the medication, the plan includes a GLP-1 fitness app, on-demand workouts, personalized meal plans, one-on-one nutrition coaching, a recipe library, monthly live sessions and a member community. Your clinician can switch you between semaglutide and tirzepatide, and WeightlessRx says dose changes don't cost extra. Billing and account support answers by email or text on weekdays.

Canceling, pausing and refunds

There's no cancellation fee, but you have to cancel by email or text at least five business days before your next billing date. A request inside that window takes effect the following cycle, and you keep access until the end of the period you've paid for. You can also pause for up to 90 days without being billed. Medication can't be refunded once it's dispensed.

Things to check first

  • Whether your checkout total is for one month or three.
  • Whether the lifetime price survives a pause or a switch between drugs.
  • Compounded semaglutide and tirzepatide aren't FDA-approved, which WeightlessRx states itself.

The Index scorecard

WeightlessRx scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month66/100
Price Transparency97/100
Nationwide Access86/100
Formulation Options66/100
Clinical Oversight86/100
Contract Flexibility43/100

The bottom line

WeightlessRx is a direct-to-consumer telehealth provider selling compounded semaglutide and tirzepatide with no separate membership or consultation fees layered on top of the drug price.

Compare the total cost of other GLP-1 programs and alternatives to WeightlessRx before deciding. A clinician should help you choose the right treatment.

Other programs to compare with WeightlessRx

These are partners: we may earn a commission if you sign up, at no cost to you.

  • Enhance MDPartner

    Semaglutide modeled $212/mo · Tirzepatide modeled $280/mo

    Enhance MD charges $212 a month for compounded semaglutide and $280 for tirzepatide at every dose, with lab work every six months included; the first month is $100 less.

  • HealthRXPartner

    Semaglutide modeled $190/mo · Tirzepatide modeled $239/mo

    HealthRX charges $190 a month for compounded semaglutide and $239 for tirzepatide month to month; the $99 and $179 it advertises are prepaid twelve-month prices.

  • SkinnyRxPartner

    Semaglutide modeled $249/mo · Tirzepatide modeled $299/mo

    SkinnyRx charges $99 for the first month of compounded semaglutide or tirzepatide, then $249 or $299 a month; prepaid plans bring semaglutide down to $199 a month.

Compare with other providers

The providers whose Cost-Efficiency Index scores sit closest to WeightlessRx's. See the alternatives to WeightlessRx.

Explore more provider reviews

Pricing, states and verification reflect WeightlessRx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on WeightlessRx's site. Not medical advice; see our disclosure.

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