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Alternatives

Alternatives to PrescrYbe

PrescrYbe scores 74/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.

Read the PrescrYbe review →CoreAge Rx vs PrescrYbe →

PrescrYbe at a glance

Semaglutide
$249Every 4 weeks (compounded injection; oral $279, microdose $179)
Tirzepatide
$339Every 4 weeks (compounded injection; microdose $179)
Coverage
All 50 states + DC
Brand-name GLP-1s
No, compounded only
Oral option
Yes
Pricing verified
October 2026

8 of the 8 programs below list semaglutide for less than PrescrYbe's $249 a month. 8 of the 8 list tirzepatide for less than its $339 a month.

PrescrYbe lists compounded semaglutide at $249 and tirzepatide at $339 per four-week cycle before you start, with oral semaglutide at $279 and microdose plans at $179; a four-week cycle means 13 charges a year.

Best for: Shoppers who want an injection, an oral tablet or a microdose plan priced up front on one page, and who budget by the four-week cycle rather than the month.

What PrescrYbe does well

  • Five GLP-1 plans are priced on the weight-loss page before any questionnaire: semaglutide injection $249, tirzepatide injection $339, oral semaglutide $279, and microdose semaglutide or tirzepatide at $179
  • Offers an oral semaglutide formulation as well as weekly injections
  • Names its clinical partner, OpenLoop Health, and says plans are evaluated by board-certified clinicians, with follow-ups to adjust dosing and manage side effects
  • You can cancel at any time from your account or by email, and a full refund applies if you cancel within 72 hours before any service is delivered or if a provider finds you ineligible

Why readers look for an alternative

  • Every price is charged per four weeks, not per month, so a year is 13 charges: $3,237 for semaglutide injections rather than 12 × $249
  • Cancellations must reach support at least 72 hours before the next billing date, and a cycle that has already been charged is not refunded
  • The dispensing pharmacy is not named; the site says only that a licensed pharmacy partner fills prescriptions
  • The weight-loss FAQ describes a different kind of program (insurance help, prior authorizations, weekly group coaching, lab testing) than the cash-pay medication plans priced above it, so confirm what your plan includes before paying
  • The site claims all 50 states and D.C. but adds that some services may not be available everywhere, and it publishes no state-by-state list
  • Compounded semaglutide and tirzepatide are not FDA-approved products
  1. Partner
    01A

    CoreAge Rx

    CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with PrescrYbe: $150/mo less for semaglutide · $190/mo less for tirzepatide · no oral option

    Visit CoreAge Rx CoreAge Rx vs PrescrYbe →
  2. 02C

    Science & Co

    Declares in its own footer that it is not a compounding facility, and explains its own asterisk in its own FAQ — two disclosures most of this market never makes.

    Sema
    $149/moMonth-to-month; $79 only on a twelve-month plan
    Tirz
    $199/moMonth-to-month; $125 only on a twelve-month plan
    Coverage
    Not disclosed
    Brand
    Compounded

    Compared with PrescrYbe: $100/mo less for semaglutide · $140/mo less for tirzepatide · no oral option

    Visit Science & Co Science & Co vs PrescrYbe →
  3. 03C

    Pallas Health

    Prices both molecules openly and bills them in 12-week blocks — $597 and $897 up front, with no monthly option to fall back on.

    Sema
    $199/moAverage — Pallas's own figure for $597 billed every 12 weeks, its only cadence; $139 covers the first 4 weeks
    Tirz
    $299/moAverage — Pallas's own figure for $897 billed every 12 weeks, its only cadence; $179 covers the first 4 weeks
    Coverage
    Most states
    Brand
    Compounded

    Compared with PrescrYbe: $50/mo less for semaglutide · $40/mo less for tirzepatide · no oral option

    Visit Pallas Health Pallas Health vs PrescrYbe →
  4. 04C

    NextMeds

    NextMeds is a compounded-GLP-1 telehealth platform naming a real clinical group (Lion MD, led by two NPI-verifiable physicians) and six named compounding pharmacies — unusually transparent on that front.

    Sema
    $79/moStarting dose, promotional rate, compounded
    Tirz
    $129/moStarting dose, promotional rate, compounded
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with PrescrYbe: $170/mo less for semaglutide · $210/mo less for tirzepatide · no oral option

    Visit NextMeds NextMeds vs PrescrYbe →
  5. 05C

    Jyra Health

    Jyra Health is a compounded GLP-1 telehealth clinic charging $175/mo (semaglutide) or $199/mo (tirzepatide) month-to-month, discounted to $139/mo and $179/mo respectively on a 3-month prepaid plan.

    Sema
    $175/moAll doses, compounded
    Tirz
    $199/moAll doses, compounded
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with PrescrYbe: $74/mo less for semaglutide · $140/mo less for tirzepatide · no oral option

    Visit Jyra Health Jyra Health vs PrescrYbe →
  6. 06C

    DoctorAdam

    DoctorAdam is a Shopify-storefront telehealth company selling compounded oral (sublingual) and injectable semaglutide and tirzepatide plus NAD+/glutathione add-ons, prescribed by a named roster of six MD/NP prescribers.

    Sema
    $129/moStarting dose, compounded oral
    Tirz
    $199/moStarting dose, compounded oral
    Coverage
    44 states
    Brand
    Compounded

    Compared with PrescrYbe: $120/mo less for semaglutide · $140/mo less for tirzepatide

    Visit DoctorAdam DoctorAdam vs PrescrYbe →
  7. 07C

    Aspen

    Aspen Health is a cash-pay telehealth platform spanning weight loss, hair health, longevity, and sexual wellness.

    Sema
    $179/moAll doses, compounded
    Tirz
    $179/moAll doses, compounded
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with PrescrYbe: $70/mo less for semaglutide · $160/mo less for tirzepatide · no oral option

    Visit Aspen Aspen vs PrescrYbe →
  8. 08C

    Amble

    Amble is a managed-services telehealth platform (by its own terms, not itself a medical facility or pharmacy) selling compounded semaglutide and tirzepatide at IDENTICAL prices on a commitment-length pricing table: $179/mo with no commitment.

    Sema
    $179/moAll doses, compounded
    Tirz
    $179/moAll doses, compounded
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with PrescrYbe: $70/mo less for semaglutide · $160/mo less for tirzepatide · no oral option

    Visit Amble Amble vs PrescrYbe →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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