Clume Health review
Clume Health charges one $259 monthly price for its Signature program whichever GLP-1 a provider picks and whichever route you take, names its four dispensing pharmacies with addresses, and advertises a $199 figure that matches nothing it sells.
- Semaglutide
- $259/month month-to-month (one Signature price covers semaglutide or tirzepatide, oral or injectable; $186/mo needs a 52-week plan)
- Tirzepatide
- $259/month month-to-month (the same Signature price; $186/mo needs a 52-week plan)
- Coverage
- All 50 states
- Brand-name
- Compounded only
Semaglutide · modeled / year
$3,108
Tirzepatide · modeled / year
$3,108
Pricing verified September 2026
The Index scorecard
Clume Health scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Names all four dispensing pharmacies with street addresses, phone numbers and websites, so a buyer can look up who actually compounds the prescription
- The price is published before the intake and covers the consultation, ongoing oversight, the medication and delivery
- One figure covers semaglutide, tirzepatide, oral and injectable, so switching molecule or route does not change the bill
- Names OpenLoop as the clinical partner in the terms, the privacy policy and the telehealth consent
- Cancellation is by email or through the portal at any time, with no early-termination fee stated
The tradeoffs
- Both headline prices on the homepage match nothing on sale: "*$199/month" against real floors of $259 and $219, and "*$159/month" against $216 — and neither asterisk resolves to a footnote
- The cheaper monthly figures are commitments rather than rates: $186 a month requires a 52-week plan and $200 a month a 12-week one
- One price covers two molecules and two routes, so no drug-specific or form-specific figure is published at all
- The four pharmacies are named but never designated 503A or 503B, and the terms reserve transfers between them for "fulfillment, availability, pricing, or operational reasons"
- The refund policy states in capitals that no refund will be issued on cancellation for the current month or any prior month
- The refund policy promises a 24/7 patient support line while no phone number appears anywhere on the site — support is email only
- No clinician is named, and the seller's own street address is not published, though Iowa law and a Polk County venue are
The bottom line
Best for: Readers who want the dispensing pharmacies named up front and do not need the price broken out by molecule. Clume Health charges one $259 monthly price for its Signature program whichever GLP-1 a provider picks and whichever route you take, names its four dispensing pharmacies with addresses, and advertises a $199 figure that matches nothing it sells.
Ranked #66 of 529 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 528 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Clume Health.
- #45NiceRx— NiceRx is a compounded GLP-1 telehealth platform charging $199/mo for semaglutide and $299/mo for tirzepatide on an ongoing month-to-month basis (first month discounted to $99 and $199 respectively).76/100
- #46Vytora Health— Vytora Health (Wasef Health, PC) is a 50-state-plus-DC telehealth platform selling flat-rate compounded semaglutide and tirzepatide alongside retail-priced brand-name Mounjaro and Zepbound ($1,399/mo each).76/100
- #47Rylo Health— Rylo Health is a compounded GLP-1/NAD+/peptide telehealth platform operating in all 50 states through Lone Star Virtual Health PLLC and dispensing via VialsRX in Houston, TX.75/100
- #48Synergy Rx— Brand Wegovy, Ozempic or Mounjaro when clinically appropriate, with unlimited round-the-clock clinical contact — at prices its own site never shows.72/100
- #49Peter MD— One account across six verticals — TRT, ED, weight loss, GLP-1, men's hair loss and NAD+ — from a physician-prescribed telehealth brand running since 2021, at a renewal price ($249/mo tirzepatide) well above its own $149 first-month headline.72/100
- #50EdgeRx— The best clinical documentation of any newly added row — a named Chief Medical Advisor and a named 503A pharmacy — but it's a men's-only platform, not a fit for every reader.74/100
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Pricing, states and verification reflect Clume Health's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Clume Health's site. Not medical advice; see our disclosure.