Onyx Weight Loss review
Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.
- Semaglutide
- $228/mo (starting dose, compounded)
- Tirzepatide
- $280/mo (starting dose, compounded)
- Coverage
- 8 states
- Brand-name
- Compounded only
Semaglutide · modeled / year
$2,736
Tirzepatide · modeled / year
$3,360
The Index scorecard
Onyx Weight Loss scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Competitive entry pricing: semaglutide from $228/mo and tirzepatide from $280/mo with medication + supplies included
- Nurse-practitioner-led care: founder Tasha Vangile FNP-C (20+ years) and Stephanie Robison APRN-CNP (27 years experience)
- Low-cost $99/mo GLP-1 microdosing option for patients who prefer a gradual titration start
- Strive Pharmacy partnership implies compounded 503A-quality supply chain from a known pharmacy
- Multi-modal clinic: GLP-1 + peptides + HRT + nutrition coaching available under one provider team
The tradeoffs
- Only 8 states (NC, CO, ME, VT, VA, IA, NH, PA) — excludes the majority of the US
- No LegitScript certification; credentialing evidence limited to local 2025 Best of Iredell award
- Specific drug names (semaglutide/tirzepatide) never stated on website; compounded status inferred, not disclosed
- Labs not included or mentioned; no baseline bloodwork protocol published
- Pricing shown as 'Starting at' with no dose-escalation tier pricing disclosed publicly
The bottom line
Best for: Cost-first shoppers who want nP-led GLP-1 telehealth across 8 states; sema from $228/mo or tirz from $280/mo, med+ship incl. Onyx Weight Loss is a nurse-practitioner-led telehealth clinic based in Mooresville, NC, offering GLP-1 and GLP-1/GIP weight-loss medications alongside peptides and HRT across 8 states.
Ranked #258 of 492 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 491 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Onyx Weight Loss.
- #257Mint Medical Clinic— Mint Medical Clinic is a hybrid Utah practice with in-person locations in Sandy and Layton plus telehealth, offering compounded semaglutide and tirzepatide from $299/month.59/100
- #259Potere Health MD— Potere Health MD is a Utah-based, physician-led weight loss clinic offering semaglutide and tirzepatide in both FDA-approved and compounded forms via telehealth and in-person visits.59/100
- #260Velvet Rx— Velvet Rx (velvetrx.com) is a cash-pay telehealth platform offering compounded semaglutide, compounded tirzepatide, and an oral GLP-1 across three publicly-listed SKUs ranging from $139 to $199 'today'…59/100
- #261BloomWell Rx— BloomWell Rx is a 100% online telehealth service offering personalized compounded GLP-1 weight loss — semaglutide (from $199/mo) and tirzepatide/GLP-1+GIP (from $249/mo) — after a free visit, plus wellness…58/100
- #262Carocare Wellness— Carocare Wellness is a medically guided clinic in Houston, Texas offering in-person, provider-supervised GLP-1 weight loss alongside IV hydration, NAD+ and routine wellness visits.58/100
- #263Elara MD— Elara MD is a weight-loss and wellness telehealth platform offering weekly injectable GLP-1 therapy alongside a peptide menu (NAD+, sermorelin, glutathione).58/100
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Pricing, states and verification reflect Onyx Weight Loss's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Onyx Weight Loss's site. Not medical advice; see our disclosure.