ZYP Medical Review: Price, Pros & Cons

ZYP Medical doesn't charge a flat monthly fee. You pay for the medication you order, and the price depends on your dose and how much you buy at once. A higher dose uses up a vial faster, so the same vial covers fewer weeks. ZYP quotes each order as a total plus a monthly equivalent, and says a "two-month" plan can last seven weeks or nine depending on your dose.

Published starter totals are $399 for ten weeks of compounded semaglutide, advertised as a $160 monthly average, or $450 for the two-month tirzepatide injection starter, advertised as $225 monthly. Those are initial courses; the ongoing dose-specific injection bill needs confirmation. New patients start with a starter plan paid in full. Compounded semaglutide comes as a 10-week starter that steps from 0.25 mg to 0.5 mg to 1 mg, with a 12-week version too. Tirzepatide's default is a two-month starter, 2.5 mg for four weeks then 5 mg, with a check-in at week seven before you reorder. A three-month tirzepatide plan is also offered. Semaglutide refills are capped at $350 per order at any dose.

The price includes supplies, cold-pack shipping and unlimited messages with your provider. There's no membership. You can pay with HSA or FSA cards, or split an order with Affirm at a slightly higher total. ZYP doesn't bill insurance.

ZYP is run by Josh Peterson, a board-certified family nurse practitioner, from a clinic in Gretna, Nebraska, in the Omaha metro. He treats weight-loss patients in person there, or by telehealth in a short list of states, so check that yours is on it when you book. He's also the person you text during treatment.

The visit comes in two lengths: a 60-minute Deep Dive for people new to GLP-1s, or a 30-minute Power Consult if you've taken them before. The weight-loss page calls the first consult free, but the current site footer lists $75 for the Deep Dive and $39.99 for the Power Consult. Ask which applies when you book.

Prescriptions go to licensed 503A compounding pharmacies, which make each order for a named patient. ZYP doesn't name them. Its formula includes vitamin B6, with a B12 and glycine version available at extra cost. Tirzepatide ODT costs $250 for a thirty-day supply. A separate chewable product is $199 for thirty tablets or $499 for ninety; the provider determines dosing frequency, so tablet counts do not by themselves establish a monthly price. Most patients get their medication three to five business days after the visit.

ZYP's refund policy is strict. Medication isn't refundable once the pharmacy ships it, and consult fees aren't refundable once the visit is done. On prepaid and multi-vial plans, the most you'll get back if you cancel before a later vial ships is $100. There are no partial refunds for unused medication, dose changes or stopping early.

If a package arrives damaged or warm, text within 24 hours of delivery and ZYP will review a replacement. There's no contract, and month-to-month supplies are offered at every dose, so you don't have to prepay for months you may not need.