Signos Review: Price, Pros & Cons

Signos is built around a continuous glucose monitor. Every plan includes the Stelo sensor by Dexcom, two sensors a month, and the Signos app, which reads your glucose every few minutes and pairs it with meal logs, workouts and weight to suggest what to eat next or when to move.

Signos sells these monitor plans in one-, three- and six-month terms, and the longer the term, the lower the monthly price. Six-month plans ship in two three-month bundles and renew automatically every six months. The monitor plans don't include any medication.

A GLP-1 prescription is a separate route. The Signos+ plan pairs a clinician-prescribed GLP-1 with the monitor and app, starting at $199 a month on a three- or six-month treatment plan. Its terms describe the medication subscription, run by OpenLoop Health, as offered in all 50 states and D.C. Yet its FAQ says Signos doesn't currently offer prescription medication. Before you start the GLP-1 intake, ask support which drug you'd get, whether it's available in your state, and what the total comes to over the plan.

Signos says it's a technology and wellness company, not a medical practice. Apart from its registered dietitians, it doesn't employ clinicians. Prescribing is done by OpenLoop Health and other networks of U.S.-licensed clinicians, who decide on their own whether you qualify for a compounded GLP-1.

Under the terms, the medication subscription starts when you complete the intake form, and that's when you're charged for the first month. It includes access to OpenLoop providers, medication where appropriate, and online support. OpenLoop contracts with outside pharmacies to fill prescriptions. The terms name four: RedRock Pharmacy in Utah, Health Warehouse in Kentucky, Precision Medicine in New York and Triad Rx in Alabama. To cancel the medication subscription, give at least 72 hours' notice before your billing date.

The two parts of Signos follow different rules.

• Monitor plans: all sales are final, because the sensors are regulated medical devices and can't be returned. Cancel auto-renewal in the app at least 24 hours before your term ends. There are no prorated refunds, and canceling a three- or six-month plan early can trigger a cancellation fee.
• GLP-1 subscription: if an OpenLoop clinician turns you down for a medical reason, you get a full refund. Otherwise, any approved refund covers only your most recent billing cycle. Damaged or incorrect medication is replaced by the pharmacy if you report it right away.

Signos makes the most sense if you want to learn how food and movement affect your glucose, with or without a GLP-1. If you're already on a GLP-1 elsewhere, its part-time "GLP-1 Essentials" monitor program is designed for that and doesn't include medication. Compounded GLP-1s aren't FDA-approved.