Ryze Rx Review: Price, Pros & Cons
Ryze Rx is a prescription telehealth platform for weight loss, TRT and peptide therapy, prescribing through board-certified physicians and shipping from US-licensed compounding pharmacies.
In this review
Prices at a glance
- Semaglutide
- Not disclosedVials from $119; duration depends on dose
- Tirzepatide
- Not disclosedVials from $199; duration depends on dose
- Coverage
- All 50 states
- Brand-name
- Not confirmed
Who Ryze Rx may suit
Shoppers who want compounded GLP-1s plus a broad TRT and peptide menu on one platform.
Where the value is
- Lists injectable semaglutide and tirzepatide by vial strength, plus oral versions of both drugs
- Physician consultation, ongoing clinical support and shipping are included
- Licensed providers serve all 50 states
- Terms allow cancellation before the next renewal date
The tradeoffs
- The injectable catalog prices vials, so confirm how many weeks your prescription covers before treating a figure as a monthly cost
- Pharmacy partners are not named
- No detailed prescription refund policy is published
- The contact number in its terms uses a 555 placeholder
How Ryze Rx prices a vial
Ryze Rx doesn't sell a flat monthly plan. It prices compounded GLP-1s by the vial, and the price climbs with the strength your provider prescribes. Compounded tirzepatide comes in 2 ml vials:
| Tirzepatide vial | Price |
|---|---|
| 5 mg | $199 |
| 10 mg | $249 |
| 15 mg | $279 |
| 20 mg | $299 |
| 25 mg | $329 |
| 30 mg | $359 |
There are also two three-month tirzepatide kits. One bundles the 5, 10 and 15 mg vials for $499. The other bundles 20, 25 and 30 mg for $799. Compounded semaglutide is sold the same way, in 1 ml vials that cost more as the strength goes up.
How long a vial lasts depends on your weekly dose, so ask your provider how many weeks your vial covers. That's the number that turns a vial price into a monthly cost. Every product is FSA and HSA eligible, and you don't need insurance.
Considering Ryze Rx?
Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.
What comes with a prescription
You fill out an online evaluation. Ryze Rx says a board-certified physician licensed in your state reviews it within 24 hours and prescribes a protocol, and that it aims to get you from evaluation to delivery in about 48 hours. After that you get monthly check-ins, dose adjustments and round-the-clock messaging with your provider.
Medication ships free by two-day delivery from a U.S.-licensed compounding pharmacy, in discreet, temperature-controlled packaging. Ryze Rx doesn't name the pharmacy. The same account sells testosterone therapy and peptides if you want those later.
Who you're dealing with
The company behind the site is Ryze RX LLC in Austin, Texas. It isn't a pharmacy itself. Its terms give support by email, and they list a phone number in the 555 range, which is the kind used as a placeholder. Use email to reach support until a working number is confirmed.
Its terms say you must be 18 or older and live in a state it covers, so confirm yours at the start of the evaluation.
Renewals and canceling
Subscription plans renew automatically until you cancel. The terms say you can cancel any time before your next renewal date by emailing support. Ryze Rx doesn't publish a refund policy, and its terms don't say whether a declined prescription is refunded or what happens to a kit you stop partway through. Get those answers in writing before you buy a three-month kit, since that's the largest single charge on the site.
The Index scorecard
Ryze Rx scored on our six Cost-Efficiency Index factors. See the methodology.
The bottom line
Ryze Rx is a prescription telehealth platform for weight loss, TRT and peptide therapy, prescribing through board-certified physicians and shipping from US-licensed compounding pharmacies.
Compare the total cost of other GLP-1 programs and alternatives to Ryze Rx before deciding. A clinician should help you choose the right treatment.
Other programs to compare with Ryze Rx
These are partners: we may earn a commission if you sign up, at no cost to you.
Enhance MDPartner
Semaglutide modeled $212/mo · Tirzepatide modeled $280/mo
Enhance MD charges $212 a month for compounded semaglutide and $280 for tirzepatide at every dose, with lab work every six months included; the first month is $100 less.
HealthRXPartner
Semaglutide modeled $190/mo · Tirzepatide modeled $239/mo
HealthRX charges $190 a month for compounded semaglutide and $239 for tirzepatide month to month; the $99 and $179 it advertises are prepaid twelve-month prices.
SkinnyRxPartner
Semaglutide modeled $249/mo · Tirzepatide modeled $299/mo
SkinnyRx charges $99 for the first month of compounded semaglutide or tirzepatide, then $249 or $299 a month; prepaid plans bring semaglutide down to $199 a month.
Compare with other providers
The providers whose Cost-Efficiency Index scores sit closest to Ryze Rx's. See the alternatives to Ryze Rx.
- Zealthy— Zealthy is a broad telehealth platform whose weight-loss arm sells GLP-1s several ways, including an insurance-routed path for branded Ozempic, Wegovy, Zepbound and Mounjaro (advertised 'as low as $25/month' if coverage comes through) and an all-in compounded bundle.63/100
- Hone Health— Hone Health's only GLP-1 is compounded liraglutide, a daily injection at $160 a month plus a $25 or $155 monthly membership, and you start with a $65 lab panel and a video visit with a physician.63/100
- Chia— Chia charges $349 a month for compounded semaglutide and $399 for tirzepatide month to month; the "from $249" on its product pages is a committed multi-month rate.63/100
- TD Tele-Doc Weight Loss— TD Tele-Doc is a small, Richmond, VA-based virtual weight-loss clinic offering semaglutide 'starting at $199' -- but that price sits beside an insurance-eligibility check rather than standing as a flat cash rate.62/100
- Jently— Jently publishes retail monthly prices of $199 semaglutide and $259 tirzepatide, plus lower founding-member offers that need confirmation. MD Integrations supplies clinicians and Precision Compounding Pharmacy is named for fulfillment.62/100
- Potere Health MD— Potere Health MD is a Utah-based, physician-led weight loss clinic offering semaglutide and tirzepatide in both FDA-approved and compounded forms via telehealth and in-person visits.62/100
Pricing, states and verification reflect Ryze Rx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Ryze Rx's site. Not medical advice; see our disclosure.