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Best-value alternatives

Alternatives to Ryze Rx

Ryze Rx scores 54/100 on our Cost-Efficiency Index (ranked #364 of 539). Here are the closest-ranked programs that beat it, plus our #1 pick — all scored the same way.

Read the Ryze Rx review →CoreAge Rx vs Ryze Rx →
  1. Our #1 pick
    01A

    CoreAge Rx

    Ranked #1

    Best value in the ranking: both molecules at one flat, all-50 price with no teaser step-ups — the lowest true cost of ownership, not the lowest teaser.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded
    Visit CoreAge Rx CoreAge Rx vs Ryze Rx →
  2. 02C

    Rixa Health

    Ranked #363

    Rixa Health is a telehealth GLP-1 clinic led by named medical director Timothy Scott, D.O., serving 45 states with a wide medication menu (compounded semaglutide, tirzepatide, an oral option, and retatrutide).

    Sema
    Not disclosed
    Tirz
    Not disclosed
    Coverage
    All 50 states
    Brand
    Compounded
    Visit Rixa Health Rixa Health vs Ryze Rx →
  3. 03C

    Pomegranate Health

    Ranked #362

    Pomegranate Health sells compounded semaglutide and tirzepatide with no membership and no consultation fee.

    Sema
    $119/mo (starting price, compounded)
    Tirz
    $149/mo (Starter tier, compounded)
    Coverage
    Multi-state
    Brand
    Compounded
    Visit Pomegranate Health Pomegranate Health vs Ryze Rx →
  4. 04C

    NuBloom

    Ranked #361

    NuBloom is a women's metabolic-health telehealth practice founded and medically led by Dr. Marianne Pinkston Mueller.

    Sema
    Not disclosed
    Tirz
    $249/mo (microdose tier, compounded)
    Coverage
    49 states
    Brand
    Compounded
    Visit NuBloom NuBloom vs Ryze Rx →
  5. 05C

    Mirabel Meds

    Ranked #360

    Mirabel Meds is a 'luxury' nationwide GLP-1 telehealth brand (found at gomirabelmeds.com after the mirabelmeds.com domain turned out to be a dead deployment) offering semaglutide, tirzepatide.

    Sema
    Not disclosed
    Tirz
    Not disclosed
    Coverage
    All 50 states
    Brand
    Yes
    Visit Mirabel Meds Mirabel Meds vs Ryze Rx →
  6. 06C

    Metaboost Rx

    Ranked #359

    Metaboost Rx is a concierge GLP-1 telehealth platform advertising 'from $249/mo' semaglutide and 'from $299/mo' tirzepatide on its homepage, but its own product pages decline to confirm or itemize those numbers.

    Sema
    $249/mo (starting dose, compounded)
    Tirz
    $299/mo (starting dose, compounded)
    Coverage
    Multi-state
    Brand
    Compounded
    Visit Metaboost Rx Metaboost Rx vs Ryze Rx →
  7. 07C

    Medi-Weightloss

    Ranked #358

    Medi-Weightloss is a 130+ location, independently-operated (franchise) in-person weight loss clinic network offering compounded semaglutide and tirzepatide at $99 and $199 first-month promotional rates.

    Sema
    $99/mo (starting dose, first-month rate, plus a separate fee, compounded)
    Tirz
    $199/mo (starting dose, first-month rate, plus a separate fee, compounded)
    Coverage
    Multi-state
    Brand
    Yes
    Visit Medi-Weightloss Medi-Weightloss vs Ryze Rx →
  8. 08C

    MANÜ Telehealth

    Ranked #357

    MANU Telehealth advertises GLP-1 pricing exclusively in per-day terms ('from $4/day' or '$5/day' depending on the page), which understates the true monthly cost and is never converted to a monthly total on the page itself.

    Sema
    $122/mo (starting dose, compounded)
    Tirz
    $152/mo (starting dose, compounded)
    Coverage
    Multi-state
    Brand
    Compounded
    Visit MANÜ Telehealth MANÜ Telehealth vs Ryze Rx →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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