Alternatives
Alternatives to Rx.com
Rx.com scores 77/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.
Rx.com at a glance
- Semaglutide
- $175/moMonth-to-month; $165 on three months, $146 on six and $99 on twelve, prepaid
- Tirzepatide
- $285/moMonth-to-month; $265 on three months, $259 on six and $149 on twelve, prepaid
- Coverage
- 47 states on its program page; product pages say 49
- Brand-name GLP-1s
- No, compounded only
- Oral option
- No
- Pricing verified
- October 2026
4 of the 8 programs below list semaglutide for less than Rx.com's $175 a month. 7 of the 8 list tirzepatide for less than its $285 a month.
Offers a flat price at every dose, no automatic renewals and a named dispensing pharmacy, with lower rates on prepaid plans.
Best for: Someone who will judge it by the plan card rather than the banner, and who values no auto-renewal and a named pharmacy over the lowest sticker.
What Rx.com does well
- "No automatic renewals" is printed under the plan card itself rather than buried in the terms
- Names Manifest Pharmacy in Greer, South Carolina with a full street address, and MD Integrations as the provider network, on the same page as the price
- One flat price at every dose from 2.5 mg to 15 mg, with the provider visit, injection supplies and cold shipping stated as included
- A provider who declines to prescribe does not charge for medication
Why readers look for an alternative
- The $99/mo semaglutide and $149/mo tirzepatide headlines require a 12-month prepayment of $1,188 or $1,788
- Its program page excludes Alaska, Louisiana and Mississippi, while product pages exclude only Alaska; confirm coverage before paying
- Injection only — no oral route and no brand-name lane
- A separate program page quotes higher monthly prices than its product cards; confirm your plan total at checkout
- Partner01A94/ 100Index
CoreAge Rx
CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Rx.com: $76/mo less for semaglutide · $136/mo less for tirzepatide
- 02C78/ 100Index
TeleClinic
TeleClinic's standard rate is $199 a month for compounded semaglutide and $299 for tirzepatide, locked as your dose rises, after a $79 or $149 first month; Rush Pharmacy fills every order.
- Sema
- $199/moCompounded, standard monthly rate, same at every dose; $79 first month
- Tirz
- $299/moCompounded, standard monthly rate, same at every dose; $149 first month
- Coverage
- 47 states
- Brand
- Compounded
Compared with Rx.com: $24/mo more for semaglutide · $14/mo more for tirzepatide
- 03C78/ 100Index
Sipra
Sipra's shortest GLP-1 plan is three months paid up front: $189 a month for compounded semaglutide and $249 for tirzepatide, the same at every dose, with nothing charged until a physician approves.
- Sema
- $189/mo3-month plan, $567 charged up front, same price at every dose, compounded
- Tirz
- $249/mo3-month plan, $747 charged up front, same price at every dose, compounded
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Rx.com: $14/mo more for semaglutide · $36/mo less for tirzepatide · offers an oral option
- 04C77/ 100Index
PreventiveMD
PreventiveMD is a physician-guided telehealth platform for GLP-1 weight loss and peptide therapy, offering compounded semaglutide from $83/mo all-in and compounded tirzepatide from $97/mo all-in.
- Sema
- $83/moAs low as, term not published, all-in, compounded
- Tirz
- $97/moAs low as, term not published, all-in, compounded
- Coverage
- 36 states
- Brand
- Yes
Compared with Rx.com: $92/mo less for semaglutide · $188/mo less for tirzepatide · also lists brand-name GLP-1s
- 05C77/ 100Index
Alloy
Alloy is a telehealth platform built around women's midlife health (menopause hormone therapy, skincare, sexual health) that also runs a dedicated Weight Care line offering both FDA-approved brand GLP-1s (Zepbound, Wegovy) and compounded alternatives (semaglutide, tirzepatide, liraglutide).
- Sema
- $169/moStarting dose, compounded
- Tirz
- $199/moStarting dose, compounded
- Coverage
- Multi-state
- Brand
- Yes
Compared with Rx.com: $6/mo less for semaglutide · $86/mo less for tirzepatide · also lists brand-name GLP-1s · offers an oral option
- 06C77/ 100Index
NuBloom
NuBloom is a women's metabolic-health telehealth practice founded and medically led by Dr. Marianne Pinkston Mueller.
- Sema
- $149/moMonthly plan, compounded
- Tirz
- $279/moMonthly plan, compounded; a 2.5 mg microdose plan is $249/mo
- Coverage
- 49 states
- Brand
- Compounded
Compared with Rx.com: $26/mo less for semaglutide · $6/mo less for tirzepatide
- 07C77/ 100Index
Ascend Vitality
Ascend Vitality (Ascend Vitality LLC, Sheridan WY) is a cash-pay compounded GLP-1 telehealth platform selling semaglutide injections or tablets from $199 a month and tirzepatide injections from $249 a month, with no membership fee.
- Sema
- $199/mo1-month plan, compounded
- Tirz
- $249/mo1-month plan, compounded
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Rx.com: $24/mo more for semaglutide · $36/mo less for tirzepatide · offers an oral option
- 08C77/ 100Index
FormBlends
FormBlends charges one price at every dose: $190 a month for compounded semaglutide and $239 for tirzepatide month to month, after a cheaper first month, with no membership fee.
- Sema
- $190/moAll doses, month to month, compounded
- Tirz
- $239/moAll doses, month to month, compounded
- Coverage
- Multi-state
- Brand
- Compounded
Compared with Rx.com: $15/mo more for semaglutide · $46/mo less for tirzepatide
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.