Joi + Blokes review
Joi + Blokes is a hormone-first telehealth platform running parallel women's (Joi) and men's (Blokes) programs, now including compounded GLP-1s at $199/mo semaglutide and $299/mo tirzepatide (after a discounted $99/$149 first month).
- Semaglutide
- $199/mo (quarterly plan, compounded)
- Tirzepatide
- $299/mo (quarterly plan, compounded)
- Coverage
- Coverage not published
- Brand-name
- Compounded only
Semaglutide · modeled / year
$2,388
Tirzepatide · modeled / year
$3,588
Pricing verified August 2026
The Index scorecard
Joi + Blokes scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Named Medical Director, Dr. Melissa Loseke, DO, plus a named Head Nurse Practitioner and two named Medical Advisors — real clinical attribution not disclosed by most competitors in this batch
- Separate gender-specific programs (Joi for women, Blokes for men) built around hormone health, with GLP-1 added as an integrated option alongside testosterone/perimenopause protocols
- For FDA-approved GLP-1/GIP medications specifically, insurance is accepted and the prescription routes to the patient's own local pharmacy rather than a mail-order compounder
- Every tier includes clinician consults and health coaching bundled into the price, not medication alone
The tradeoffs
- Billed in 3-month blocks, not month-to-month — the $99/$149 first-month price is promotional, and the real standing cost from month 2 is $199 (semaglutide) or $299 (tirzepatide)
- New York and New Jersey residents are explicitly called out as paying different pricing, but the site does not state the amount
- No full state-availability list is published — the safety page only says 'available in certain locations'
- No compounding pharmacy is named for the compounded line, and no LegitScript certification is mentioned anywhere on the site
- FDA issued Joi and Blokes dba Joi + Blokes a warning letter in June 2026; the letter is public in FDA's warning-letter database
The bottom line
Best for: Patients already on Joi or Blokes hormone programs who want GLP-1 added under the same clinician relationship, and are comfortable with a 3-month billing commitment. Joi + Blokes is a hormone-first telehealth platform running parallel women's (Joi) and men's (Blokes) programs, now including compounded GLP-1s at $199/mo semaglutide and $299/mo tirzepatide (after a discounted $99/$149 first month).
Ranked #384 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Joi + Blokes.
- #391Remi Meds— Remi Meds is a GLP-1 telehealth marketing platform that itself provides no medical or pharmacy services — prescriptions come through partner Beluga Health and medication is dispensed by Strive Pharmacy (Gilbert, AZ).52/100
- #392Shape Vantage— Shape Vantage (shapevantage.com) sells a single flat-rate, prepaid 3-month tirzepatide program for $399 (~$133/mo).52/100
- #393Vyora Wellness— Vyora Wellness is a compounded GLP-1 telehealth subscription priced as a genuinely flat rate $299/mo for semaglutide, $399/mo for tirzepatide that does not change as the prescribed dose is titrated up.52/100
- #394Empower Pharmacy— Empower Pharmacy is a large 503A/503B compounding pharmacy that manufactures and fulfills compounded semaglutide and tirzepatide for practitioners and telehealth companies nationwide -- it is a B2B (and refill-only B2C) fulfillment pharmacy.51/100
- #395BioGlow Health— BioGlow Health is a multi-service telehealth platform (weight loss, peptides, TRT, ED, hair loss) that does offer compounded semaglutide and tirzepatide.51/100
- #396Bloom MD— BloomMD is a telehealth platform with unusually transparent, explicitly dose-tiered pricing for compounded semaglutide and tirzepatide (both starting at $295/month, scaling up to $595/month at the highest published tirzepatide dose).51/100
The 18 programs nearest this one
- #385 Alegro Health52
- #386 CVS MinuteClinic52
- #387 EllieMD52
- #388 Hormonally Balanced52
- #389 Lyfe Rx52
- #390 PCOS Sisters52
- #397 Gaya Wellness51
- #398 JRNYS51
- #399 LIV by WellNow51
- #400 LVNG RX51
- #401 Noom51
- #402 Onyx Weight Loss51
- #403 TRT Nation51
- #404 tru Weight Loss51
- #405 Woodwork51
- #406 Try Ageless48
- #407 DadVantage Men's Health50
- #408 ElixaMD50
Pricing, states and verification reflect Joi + Blokes's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Joi + Blokes's site. Not medical advice; see our disclosure.