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Alternatives

Alternatives to Joi + Blokes

Joi + Blokes scores 56/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.

Read the Joi + Blokes review →CoreAge Rx vs Joi + Blokes →

Joi + Blokes at a glance

Semaglutide
$179/moBilled quarterly, first month $99, compounded
Tirzepatide
$249/moBilled quarterly, first month $149, compounded
Coverage
Coverage not published
Brand-name GLP-1s
Yes
Oral option
No
Pricing verified
October 2026

3 of the 8 programs below list semaglutide for less than Joi + Blokes's $179 a month. 3 of the 8 list tirzepatide for less than its $249 a month.

Joi + Blokes is a hormone-first telehealth platform running parallel women's (Joi) and men's (Blokes) programs, with compounded GLP-1s at $179/mo semaglutide and $249/mo tirzepatide (after a discounted $99/$149 first month) and a separate brand Zepbound program.

Best for: Patients already on Joi or Blokes hormone programs who want GLP-1 added under the same clinician relationship, and are comfortable with a 3-month billing commitment.

What Joi + Blokes does well

  • Named Medical Director, Dr. Melissa Loseke, DO, plus a named Head Nurse Practitioner and two named Medical Advisors, more clinical names than most programs we track
  • Separate gender-specific programs (Joi for women, Blokes for men) built around hormone health, with GLP-1 added as an integrated option alongside testosterone/perimenopause protocols
  • For FDA-approved GLP-1/GIP medications specifically, insurance is accepted and the prescription routes to the patient's own local pharmacy rather than a mail-order compounder
  • Every tier includes clinician consults and health coaching bundled into the price, not medication alone
  • A brand Zepbound program is offered too: $99/mo for visits and coaching, billed quarterly, with the medication bought from LillyDirect at $349 to $599 a month by dose

Why readers look for an alternative

  • Billed in 3-month blocks, not month-to-month — the $99/$149 first-month price is promotional, and the standing cost from month 2 is $179 (semaglutide) or $249 (tirzepatide)
  • New York and New Jersey residents are explicitly called out as paying different pricing, but the site does not state the amount
  • No full state-availability list is published — the safety page only says 'available in certain locations'
  • No compounding pharmacy is named for the compounded line, and no LegitScript certification is mentioned anywhere on the site
  • FDA issued Joi and Blokes dba Joi + Blokes a warning letter in June 2026; the letter is public in FDA's warning-letter database
  1. Partner
    01A

    CoreAge Rx

    CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with Joi + Blokes: $80/mo less for semaglutide · $100/mo less for tirzepatide · compounded only, no brand-name GLP-1s

    Visit CoreAge Rx CoreAge Rx vs Joi + Blokes →
  2. 02C

    WellMedr

    Partner

    Names its pharmacy, its clinician network and the FDA's compounding caveat right on the pricing page — then quotes only sale prices for its compounded plans and bills on a cycle its own pages describe as four weeks in one place and 21 days in another.

    Sema
    Not disclosedSale price only, no standing rate
    Tirz
    Not disclosed"Starting at" only, no standing rate
    Coverage
    Multi-state
    Brand
    Yes

    Compared with Joi + Blokes: offers an oral option

    Visit WellMedr WellMedr vs Joi + Blokes →
  3. 03C

    Midi Health

    Midi Health is a telehealth platform built around midlife women's hormone health (menopause, HRT) that also runs a genuine GLP-1 weight-management track with its own dedicated pricing page.

    Sema
    $166/mo0.5 mg dose, plus a separate fee, compounded
    Tirz
    $210/mo2.5 mg dose, plus a separate fee, compounded
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with Joi + Blokes: $13/mo less for semaglutide · $39/mo less for tirzepatide · compounded only, no brand-name GLP-1s

    Visit Midi Health Midi Health vs Joi + Blokes →
  4. 04C

    Refills

    Refills is a multi-category telehealth platform offering compounded GLP-1 treatment through independent clinician networks, with Hallandale and Perfect Rx named as dispensing partners.

    Sema
    Not disclosed
    Tirz
    Not disclosed
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Joi + Blokes: compounded only, no brand-name GLP-1s

    Visit Refills Refills vs Joi + Blokes →

    Regulatory note: the FDA issued a warning letter to Refills Health, LLC dba Refills Health in February 2026. We still list and link to Refills; you should know the letter is on the public record before you decide.

  5. 05C

    Framework

    Framework offers doctor-guided compounded GLP-1 plans with nutrition support, while the medication price appears after intake.

    Sema
    Not disclosed
    Tirz
    Not disclosed
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Joi + Blokes: compounded only, no brand-name GLP-1s

    Visit Framework Framework vs Joi + Blokes →
  6. 06C

    myRocky

    MyRocky lists branded GLP-1 products, oral Rybelsus and a separate $397 compounded semaglutide offer. The program adds a $99 monthly care fee, and the medication pack prices need a confirmed supply length.

    Sema
    Monthly medication cost not established (Ozempic listed $1,409; compounded offer $397, supply to confirm; plus $99/mo program fee)
    Tirz
    Monthly medication cost not established (Mounjaro listed $1,509; supply to confirm; plus $99/mo program fee)
    Coverage
    Multi-state
    Brand
    Yes

    Compared with Joi + Blokes: offers an oral option

    Visit myRocky myRocky vs Joi + Blokes →
  7. 07C

    Boston Medical Group

    Boston Medical Group is an established medical group running a 12-week compounded GLP-1 weight-loss program.

    Sema
    $199/moStarting strength, rising with dose, compounded
    Tirz
    Not disclosed
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Joi + Blokes: $20/mo more for semaglutide · compounded only, no brand-name GLP-1s

    Visit Boston Medical Group Boston Medical Group vs Joi + Blokes →
  8. 08C

    HelloWellness

    HelloWellness sells compounded GLP-1 plans paid up front and renewed every 11 weeks, so its advertised three-month equivalents understate the ongoing calendar-month average.

    Sema
    ~$157.18/mo equivalent average ($399 upfront, then every 11 weeks; compounded)
    Tirz
    ~$196.58/mo equivalent average ($499 upfront, then every 11 weeks; compounded; cadence conflict)
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with Joi + Blokes: $21.82/mo less for semaglutide · $52.42/mo less for tirzepatide · compounded only, no brand-name GLP-1s

    Visit HelloWellness HelloWellness vs Joi + Blokes →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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