ARSYNL Rx Review: Price, Pros & Cons
ARSYNL offers compounded semaglutide and tirzepatide injections with provider review, a protocol-based price ladder and nationwide shipping.
In this review
Compounded drugs are not FDA-approved. Treatment requires a clinician's assessment. Understand compounded GLP-1 treatment.
Prices at a glance
- Semaglutide
- $219/moStarting protocol, compounded injection; higher protocols cost more
- Tirzepatide
- $269/moStarting protocol, compounded injection; higher protocols cost more
- Coverage
- All 50 states (per therapies page)
- Brand-name
- Not confirmed
Semaglutide · estimated annual cost
$2,628
Tirzepatide · estimated annual cost
$3,228
Who ARSYNL Rx may suit
Cost-first shoppers who want a needle-free tirzepatide hypospray option alongside standard compounded injections, from a veteran-founded telehealth brand.
Where the value is
- Public one-month starting protocols are $219 semaglutide and $269 tirzepatide
- Names the Arora Health provider network
- Therapies page says delivery is available in all 50 states
- Supplies, consultation and shipping are included
The tradeoffs
- Higher protocols cost more than the advertised starting rate
- Tirzepatide title says B12 while the description says B6; confirm the additive in your prescription
- No individual medical director or dispensing pharmacy is named
How ARSYNL Rx prices its GLP-1s
ARSYNL Rx sells three compounded GLP-1 products: a weekly semaglutide injection, a weekly tirzepatide injection, and a needle-free tirzepatide spray it calls the HypoSpray. Each one is priced as a flat monthly plan with the medication included, and there's no separate membership fee. Consultations, injection supplies and shipping are part of the price.
The starting price only covers the lowest protocol. Each product has a ladder of strengths, and its listed price range runs well above the starting figure. Ask what your expected maintenance dose will cost before you sign up, not just what month one costs.
A three-month prepay brings the monthly rate down a little compared with paying month to month. First-time customers also get $100 off their first order. ARSYNL doesn't take insurance.
Considering ARSYNL Rx?
Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.
Three formats to choose from
The semaglutide injection is compounded with vitamin B12 and comes in four protocols that cover the step-up from the starting dose to maintenance. The tirzepatide injection is compounded with vitamin B6 and runs in five steps from 2.5 mg to 15 mg a week. Its product name mentions B12, but the description says B6, so ask which one is in your vial.
The HypoSpray is a tirzepatide spray applied to the skin daily instead of injected. ARSYNL sells it in six protocols, from 10 mg to 60 mg a month, and says one bottle is exactly four weeks of supply. You prime the pump before the first use of each new bottle.
Who prescribes it
You complete an online medical intake, and a U.S.-licensed provider reviews it, plus labs when needed. If you've had labs in the past six months, ARSYNL may be able to use them. State rules can require a photo of you and your photo ID. The prescribers come from the Arora Health provider network of physicians and nurse practitioners, and ARSYNL advertises round-the-clock messaging with providers.
A provider reviews your tolerance before every dose increase. Medication is made by a licensed pharmacy partner that ARSYNL doesn't name, and it ships in plain packaging. Check that ARSYNL serves your state before you pay. It was founded by a veteran, and a share of its revenue goes to Shields & Stripes, a recovery program for service members and first responders.
Refunds and canceling
Prescription medication can't be returned once the pharmacy has dispensed it. After your card is charged and the package is handed to the carrier, the sale is final. Before it ships, you can log in to change your address or payment method, or cancel your subscription. Problems go through a support ticket on the contact page or the patient care phone line.
Before you order:
- Ask for the price at your expected dose, not the starting protocol.
- Confirm whether your tirzepatide contains B6 or B12.
- Cancel before the next shipment goes out if you plan to stop.
The Index scorecard
ARSYNL Rx scored on our six Cost-Efficiency Index factors. See the methodology.
The bottom line
ARSYNL offers compounded semaglutide and tirzepatide injections with provider review, a protocol-based price ladder and nationwide shipping.
Compare the total cost of other GLP-1 programs and alternatives to ARSYNL Rx before deciding. A clinician should help you choose the right treatment.
Other programs to compare with ARSYNL Rx
These are partners: we may earn a commission if you sign up, at no cost to you.
SkinnyRxPartner
Semaglutide modeled $249/mo · Tirzepatide modeled $299/mo
SkinnyRx charges $99 for the first month of compounded semaglutide or tirzepatide, then $249 or $299 a month; prepaid plans bring semaglutide down to $199 a month.
Bodybuilding Health+Partner
Semaglutide modeled $179/mo · Tirzepatide modeled $209/mo
The Bodybuilding.com brand's telehealth arm charges $179 a month for compounded semaglutide and $209 for tirzepatide, with discounts for three, six and twelve months.
Peter MDPartner
Semaglutide modeled $149/mo · Tirzepatide modeled $249/mo
One account across six verticals — TRT, ED, weight loss, GLP-1, men's hair loss and NAD+ — from a physician-prescribed telehealth brand running since 2021, at a renewal price ($249/mo tirzepatide) well above its own $149 first-month headline.
Compare with other providers
The providers whose Cost-Efficiency Index scores sit closest to ARSYNL Rx's. See the alternatives to ARSYNL Rx.
- TMates— TMates sells compounded semaglutide at $249 a month and tirzepatide at $297, the same at every dose, with lower rates down to $158 and $167 only if you prepay up to 12 months.68/100
- MadeMed— MadeMed has no month-to-month plan: compounded semaglutide is $239 a month billed $717 every three months, tirzepatide $399 billed $1,197, and both drop to $199 and $369 on a six-month plan.68/100
- Vyvron— Vyvron charges $199 every four weeks for compounded GLP-1 care at its founding-member rate, which adds up to 13 charges a year and rises to $249 once its founding spots fill.68/100
- MEDGm— MEDGm charges $299 a month for compounded semaglutide injections and $399 for tirzepatide once the $120 welcome coupon lapses, prints every plan length on its product pages, and names the four pharmacies that fill its prescriptions.67/100
- WeightWatchers Clinic— WeightWatchers Clinic (Med+) is the medical arm of WeightWatchers, prescribing brand-name GLP-1s, including the Wegovy pill and pen, with self-pay prices published and a separate monthly membership on top.67/100
- Hello Alpha— Hello Alpha is a well-established women's telehealth brand that also genuinely prescribes FDA-approved branded GLP-1s (Wegovy, Ozempic, Mounjaro, Zepbound, and orforglipron/Foundayo) rather than compounded versions.67/100
Pricing, states and verification reflect ARSYNL Rx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on ARSYNL Rx's site. Not medical advice; see our disclosure.