Lyfe Rx review
Lyfe Rx is a Shopify-based compounded-GLP-1 storefront charging a flat, all-inclusive $225/month for semaglutide and $299/month for tirzepatide with 'NO HIDDEN FEES OR MEMBERSHIPS,' shipping to 49 states (all but Alabama).
- Semaglutide
- $225/mo (plus a separate fee, compounded)
- Tirzepatide
- $299/mo (plus a separate fee, compounded)
- Coverage
- Coverage not published
- Brand-name
- Compounded only
Semaglutide · modeled / year
$2,700
Tirzepatide · modeled / year
$3,588
Pricing verified August 2026
The Index scorecard
Lyfe Rx scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Genuinely all-inclusive flat pricing — 'Every price covers your provider review, your medication, all medical supplies and free shipping,' with no separate membership charge unlike several competitors in this category
- 49-state coverage explicitly disclosed ('throughout the United States with the exception of Alabama')
- LegitScript Certified badge with a verification link displayed on the homepage
- Fast stated turnaround — orders ship within 3-5 business days of provider approval
The tradeoffs
- No dose (mg) is shown on the semaglutide or tirzepatide product listing, so a shopper cannot tell what starting dose $225/$299 actually buys before starting the intake
- No compounding pharmacy is named beyond generic '503A pharmacy' language, and no medical director or prescriber is named anywhere on the site
- Also sells non-prescription 'Tirzepatide Weight Loss Supplement' and similar products alongside prescription compounds, which can blur the line for shoppers browsing the storefront
- FDA issued Lyfe Rx a warning letter in September 2025; the letter is public in FDA's warning-letter database
The bottom line
Best for: Shoppers who want one flat all-inclusive charge with no separate membership fee, in 49 states. Lyfe Rx is a Shopify-based compounded-GLP-1 storefront charging a flat, all-inclusive $225/month for semaglutide and $299/month for tirzepatide with 'NO HIDDEN FEES OR MEMBERSHIPS,' shipping to 49 states (all but Alabama).
Ranked #389 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to Lyfe Rx.
- #391Remi Meds— Remi Meds is a GLP-1 telehealth marketing platform that itself provides no medical or pharmacy services — prescriptions come through partner Beluga Health and medication is dispensed by Strive Pharmacy (Gilbert, AZ).52/100
- #392Shape Vantage— Shape Vantage (shapevantage.com) sells a single flat-rate, prepaid 3-month tirzepatide program for $399 (~$133/mo).52/100
- #393Vyora Wellness— Vyora Wellness is a compounded GLP-1 telehealth subscription priced as a genuinely flat rate $299/mo for semaglutide, $399/mo for tirzepatide that does not change as the prescribed dose is titrated up.52/100
- #394Empower Pharmacy— Empower Pharmacy is a large 503A/503B compounding pharmacy that manufactures and fulfills compounded semaglutide and tirzepatide for practitioners and telehealth companies nationwide -- it is a B2B (and refill-only B2C) fulfillment pharmacy.51/100
- #395BioGlow Health— BioGlow Health is a multi-service telehealth platform (weight loss, peptides, TRT, ED, hair loss) that does offer compounded semaglutide and tirzepatide.51/100
- #396Bloom MD— BloomMD is a telehealth platform with unusually transparent, explicitly dose-tiered pricing for compounded semaglutide and tirzepatide (both starting at $295/month, scaling up to $595/month at the highest published tirzepatide dose).51/100
The 18 programs nearest this one
- #390 PCOS Sisters52
- #397 Gaya Wellness51
- #398 JRNYS51
- #399 LIV by WellNow51
- #400 LVNG RX51
- #401 Noom51
- #402 Onyx Weight Loss51
- #403 TRT Nation51
- #404 tru Weight Loss51
- #405 Woodwork51
- #406 Try Ageless48
- #407 DadVantage Men's Health50
- #408 ElixaMD50
- #409 Klinic50
- #410 MDLive50
- #411 Nurx50
- #412 PrescribedRX50
- #413 Remote Pharmacy50
Pricing, states and verification reflect Lyfe Rx's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Lyfe Rx's site. Not medical advice; see our disclosure.