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Provider review

RxION Health Review: Price, Pros & Cons

By The WeighLab Bench, Tools & Data Desk

RxION Health offers compounded GLP-1 injections with monthly and prepaid plans, plus brand-name Wegovy and Zepbound prescriptions.

In this review

Compounded drugs are not FDA-approved. Treatment requires a clinician's assessment. Understand compounded GLP-1 treatment.

Check RxION Health prices Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. See our disclosure.

Prices at a glance

Semaglutide
$199/moOne-month compounded subscription, all doses
Tirzepatide
$299/moOne-month compounded subscription, all doses
Coverage
Coverage not published
Brand-name
Yes

Semaglutide · estimated annual cost

$2,388

Tirzepatide · estimated annual cost

$3,588

Who RxION Health may suit

Patients who want a flat dose price and can compare the one-month subscription against prepaid supply totals.

Where the value is

  • One-month subscriptions cost $199 semaglutide and $299 tirzepatide at any dose
  • Includes consultation, medication if prescribed, injection supplies and cold-pack shipping
  • Publishes six-month totals of $594 semaglutide and $1,098 tirzepatide
  • Also offers brand-name Wegovy and Zepbound prescriptions

The tradeoffs

  • The $99/$183 monthly equivalents require six months paid upfront
  • Not available in New Jersey, Alaska or Mississippi
  • The clinician and dispensing pharmacies are not individually named
  • If treatment is declined, the medication portion is refunded but a $75 consultation fee is kept
  • Once a prescription reaches the pharmacy, cancellation and refunds are restricted

RxION's plans and what each costs

RxION Health sells compounded semaglutide and tirzepatide as weekly injections. The price is the same at every dose, so it doesn't climb as you step up. What changes the price is how many months you buy at once.

PlanSemaglutideTirzepatide
6-month supply$99/mo ($594 total)$183/mo ($1,098 total)
3-month supply$127/mo ($381 total)$220/mo ($660 total)
1-month subscription$199/mo$299/mo
1 month, no subscription$299 one timenot offered

The low monthly figures are the six-month rates, paid upfront. Each price covers the telehealth consultation and the medication if you're prescribed it, plus injection supplies, step-by-step instructions and cold-pack shipping. RxION doesn't need insurance.

Brand-name Wegovy and Zepbound are also listed as separate prescription options.

There's also a separate microdose line, lower doses of compounded semaglutide or tirzepatide with glycine added, for people whose BMI is under 25.

Considering RxION Health?

Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.

From questionnaire to delivery

You pick your medication and plan, then complete an online health questionnaire. A licensed provider reviews it and decides whether treatment fits. Some states require a short video visit before a prescription can be written. RxION isn't a pharmacy itself. Approved prescriptions are filled by licensed partner pharmacies, and RxION doesn't name them.

Once a prescription is approved and verified, orders usually ship within one to three business days, a little longer for compounded medication. Standard delivery takes two to five business days after shipping in the continental U.S. The box comes in plain packaging, and someone should be home to put it in the fridge. Compounded medication can't go to a PO box. RxION says its compounded batches are tested for potency, pH, sterility and endotoxins.

The $75 you won't get back

Pay attention to the order of events. You pay before a provider reviews you, and buying a plan doesn't guarantee approval. If you're turned down, RxION refunds the medication portion but keeps a $75 consultation fee.

Once a prescription goes to the pharmacy, the order can't be canceled, changed or refunded, whether or not it has shipped. On auto-refill plans:

  • Cancel before your renewal date and nothing is charged.
  • Cancel after the renewal payment but before provider review, and you get a refund less a 7.5% cancellation fee.
  • After the refill prescription is issued, there's no refund.

Report a lost or damaged package within 7 days of the delivery date, and a warm or damaged cold shipment within 24 hours.

Before you sign up

  • RxION isn't available in New Jersey, Alaska or Mississippi.
  • Six months at $99 is $594 due at once. If you're not sure the drug suits you, compare that with the one-month price.
  • Ask which pharmacy will fill your prescription.
  • Support runs weekdays, 9 a.m. to 6 p.m. Central.

Compounded semaglutide and tirzepatide are not FDA-approved.

The Index scorecard

RxION Health scored on our six Cost-Efficiency Index factors. See the methodology.

Normalized Cost/Month73/100
Price Transparency94/100
Nationwide Access24/100
Formulation Options79/100
Clinical Oversight81/100
Contract Flexibility55/100

The bottom line

RxION Health offers compounded GLP-1 injections with monthly and prepaid plans, plus brand-name Wegovy and Zepbound prescriptions.

Compare the total cost of other GLP-1 programs and alternatives to RxION Health before deciding. A clinician should help you choose the right treatment.

Other programs to compare with RxION Health

These are partners: we may earn a commission if you sign up, at no cost to you.

  • HealthRXPartner

    Semaglutide modeled $190/mo · Tirzepatide modeled $239/mo

    HealthRX charges $190 a month for compounded semaglutide and $239 for tirzepatide month to month; the $99 and $179 it advertises are prepaid twelve-month prices.

  • SkinnyRxPartner

    Semaglutide modeled $249/mo · Tirzepatide modeled $299/mo

    SkinnyRx charges $99 for the first month of compounded semaglutide or tirzepatide, then $249 or $299 a month; prepaid plans bring semaglutide down to $199 a month.

  • Bodybuilding Health+Partner

    Semaglutide modeled $179/mo · Tirzepatide modeled $209/mo

    The Bodybuilding.com brand's telehealth arm charges $179 a month for compounded semaglutide and $209 for tirzepatide, with discounts for three, six and twelve months.

Compare with other providers

The providers whose Cost-Efficiency Index scores sit closest to RxION Health's. See the alternatives to RxION Health.

Explore more provider reviews

Pricing, states and verification reflect RxION Health's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on RxION Health's site. Not medical advice; see our disclosure.

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