Yes Clinic Review: Price, Pros & Cons
Yes Clinic sells compounded semaglutide at $129 a month and tirzepatide at $149, flat at every dose, but the shortest plan is three months paid upfront: $387 or $447.
- Semaglutide
- $129/mo3-month plan, billed $387 upfront, same price at every dose, compounded
- Tirzepatide
- $149/mo3-month plan, billed $447 upfront, same price at every dose, compounded
- Coverage
- Not published
- Brand-name
- Compounded only
Semaglutide · modeled / year
$1,548
Tirzepatide · modeled / year
$1,788
The Index scorecard
Yes Clinic scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Every plan price is on the product pages with no quiz or account: semaglutide $387 for 3 months or $699 for 6, tirzepatide $447 or $894
- The price stays the same at every dose, and the online consultation, shipping and membership are all included at $0
- If a provider declines to prescribe, you aren't charged for medication, and a 6-month plan refunds months 4 to 6 if they aren't approved
- Cancel a subscription any time from your account or by email, and an order that hasn't been dispensed yet is refunded in full
The tradeoffs
- There is no single-month plan: the cheapest way in is three months paid upfront
- The homepage says GLP-1 programs start "From $199/month" and mentions monthly plan rates, while the product pages show only $129 and $149 a month on 3- and 6-month plans
- It doesn't name its pharmacies or its medical group, and says only that services are "not available in all states" without a list
- Its terms of use still contain unfilled template placeholders where the dispute-resolution clause and the governing-law state should be
- Dispensed medication can't be returned or refunded, even unopened
- Compounded semaglutide and tirzepatide are not FDA-approved products
The bottom line
Best for: Shoppers who can pay for three months at once and want a price that won't rise as their dose goes up. Yes Clinic sells compounded semaglutide at $129 a month and tirzepatide at $149, flat at every dose, but the shortest plan is three months paid upfront: $387 or $447.
For comparison, read our review of CoreAge Rx, one of our partners. Partners are listed first on our leaderboard; every provider is scored on the same six factors.
Other programs to compare with Yes Clinic
These are partners: we may earn a commission if you sign up, at no cost to you.
CoreAge RxPartner
Semaglutide from $99/mo · tirzepatide from $149/mo
CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.
EdenPartner
Semaglutide from $99/mo · tirzepatide from $129/mo
Eden charges $99 a month for compounded semaglutide and $129 for compounded tirzepatide, the same at every dose, with the visit, medication and shipping included.
ShedRx (Shed)Partner
Semaglutide from $199/mo · tirzepatide from $299/mo
Shed sells its GLP-1s as an injection, drops, lozenges or a daily pill, with brand-name Zepbound too; month to month, semaglutide is $199 and tirzepatide $299.
Compare with other providers
The providers whose Cost-Efficiency Index scores sit closest to Yes Clinic's. See the alternatives to Yes Clinic.
- Zenbody— Zenbody lists compounded semaglutide from $149 and tirzepatide from $179 a month as weekly injections, or from $199 and $299 as daily tablets, but those are first-month starting-dose prices and the rate after month one isn't shown until checkout.65/100
- Vital Step— Vital Step advertises compounded semaglutide "as low as $161" and tirzepatide "as low as $198" a month as injections or daily tablets, but the plan and the regular monthly price only appear once you've done the intake.65/100
- Enhanced— Enhanced sells compounded semaglutide from $89 a month and tirzepatide from $129, with the medication, clinician and follow-ups included, plus lower-priced microdose plans.65/100
- Levity— Levity is a telehealth weight-loss provider dispensing only FDA-approved branded GLP-1 medications Ozempic ($1,199/mo), Mounjaro ($1,299/mo) and Wegovy ($1,599/mo), all all-inclusive of consultation, prescription and shipping.64/100
- AlyveRx— AlyveRx (Alyve) is a telehealth platform selling compounded semaglutide and tirzepatide in both standard injection and proprietary PermeAct sublingual-drop form, plus brand Ozempic, Wegovy.64/100
- Blis MD— Blis MD is a telehealth service offering compounded semaglutide ($109/mo) and tirzepatide ($159/mo) at flat monthly rates with a free initial consultation and ongoing provider check-ins.64/100
Pricing, states and verification reflect Yes Clinic's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Yes Clinic's site. Not medical advice; see our disclosure.