Alternatives
Alternatives to Lyfe Rx
Lyfe Rx scores 68/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.
Lyfe Rx at a glance
- Semaglutide
- $225.50/moMonthly subscription, compounded; $275 as a one-time order, $206.25/mo billed every 3 months
- Tirzepatide
- $327.18/moMonthly subscription, compounded; $399 as a one-time order, $299.25/mo billed every 3 months
- Coverage
- 49 states
- Brand-name GLP-1s
- No, compounded only
- Oral option
- No
- Pricing verified
- October 2026
7 of the 8 programs below list semaglutide for less than Lyfe Rx's $225.5 a month. 7 of the 8 list tirzepatide for less than its $327.18 a month.
Lyfe Rx is an online store for compounded GLP-1s that prices semaglutide and tirzepatide all-in, with no membership: one-time orders at $275 and $399, or less on a monthly or 3-month subscription, shipping to every state but Alabama.
Best for: Shoppers who want one all-inclusive price with no separate membership, and the option to buy a single month without subscribing.
What Lyfe Rx does well
- All-inclusive pricing with no membership: the listed price covers the provider review, medication, supplies and free shipping
- Buy one month at a time, or subscribe for 18% off monthly or 25% off every 3 months, and pause or stop whenever you want
- Ships to 49 states (all but Alabama)
- Named medical director (John Marley Bernard Jr., MD) and co-medical director (Sergio Naccarato, MD), plus named nurse practitioners
- LegitScript certified
Why readers look for an alternative
- No dose is shown on either listing, so you can't tell what the price buys at higher doses
- No compounding pharmacy is named beyond a U.S.-licensed 503A pharmacy
- Its pricing page says no consultation charge is added, but the refund policy keeps a $50 intake and doctor fee if you cancel before the prescription is filled
- Filled prescriptions are final sale, even unopened
- FDA issued Lyfe Rx a warning letter in September 2025; the letter is public in FDA's warning-letter database
- Partner01A94/ 100Index
CoreAge Rx
CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.
- Sema
- $99/mo
- Tirz
- $149/mo
- Coverage
- All 50 states
- Brand
- Compounded
Compared with Lyfe Rx: $126.5/mo less for semaglutide · $178.18/mo less for tirzepatide
- 02C68/ 100Index
Alternate Health Club
Alternate Health Club, LLC offers compounded semaglutide for $129 and tirzepatide for $169 a month, with the same price at every dose.
- Sema
- $129/moAll doses, compounded
- Tirz
- $169/moAll doses, compounded
- Coverage
- Multi-state
- Brand
- Compounded
Compared with Lyfe Rx: $96.5/mo less for semaglutide · $158.18/mo less for tirzepatide
- 03C68/ 100Index
HealthHub
HealthHub is a LegitScript-certified telehealth platform (seal 46103909) selling compounded semaglutide and tirzepatide in FOUR formats standard injection, oral dissolving tablet, and a sublingual liquid.
- Sema
- $99For the first 4 weeks (starting dose, compounded; later refill prices not published)
- Tirz
- $199For the first month (starting dose, compounded; later refill prices not published)
- Coverage
- Multi-state
- Brand
- Compounded
Compared with Lyfe Rx: $126.5/mo less for semaglutide · $128.18/mo less for tirzepatide · offers an oral option
- 04C68/ 100Index
Corsica Health
Corsica Health offers one-month compounded semaglutide for $199 and tirzepatide for $299, lower prepaid three-month equivalents, and separate brand-name pill prescription services.
- Sema
- $199/moOne-month compounded plan; $149/mo equivalent on $447 three-month prepay
- Tirz
- $299/moOne-month compounded plan; $249/mo equivalent on $747 three-month prepay
- Coverage
- Multi-state
- Brand
- Yes
Compared with Lyfe Rx: $26.5/mo less for semaglutide · $28.18/mo less for tirzepatide · also lists brand-name GLP-1s · offers an oral option
- 05C68/ 100Index
Green Cap Health
Green Cap Health coordinates Texas-only compounded GLP-1 care through independent clinicians and pharmacy partners. Monthly plans cost $179 for semaglutide and $279 for tirzepatide, with lower committed-plan rates.
- Sema
- $179/moAll doses, month-to-month, compounded; $89.50 first month with code
- Tirz
- $279/moAll doses, month-to-month, compounded
- Coverage
- Texas only
- Brand
- Compounded
Compared with Lyfe Rx: $46.5/mo less for semaglutide · $48.18/mo less for tirzepatide
- 06C68/ 100Index
Semaglutide Online
Semaglutide Online sells both FDA-approved brand-name GLP-1s (billed as medication plus a separate $44/mo provider subscription) and 'all-inclusive' compounded semaglutide and tirzepatide with no separate provider fee.
- Sema
- $199/moAll-inclusive compounded; $179 elsewhere on the page, confirm current price
- Tirz
- $299/moAll-inclusive compounded
- Coverage
- Multi-state
- Brand
- Yes
Compared with Lyfe Rx: $26.5/mo less for semaglutide · $28.18/mo less for tirzepatide · also lists brand-name GLP-1s · offers an oral option
- 07C68/ 100Index
Transparent Meds
Transparent Meds offers compounded weekly semaglutide and tirzepatide injections with introductory prices of $99 and $199, then regular program fees of $229 and $349 monthly.
- Sema
- $229/moRegular rate, compounded; $99 introductory offer
- Tirz
- $349/moCompounded
- Coverage
- 45 states
- Brand
- Compounded
Compared with Lyfe Rx: $3.5/mo more for semaglutide · $21.82/mo more for tirzepatide
- 08C68/ 100Index
ElleS
ElleS offers compounded GLP-1 injections and oral options alongside hormone, hair and longevity care; the $179 headline is a microdose semaglutide plan.
- Sema
- $179/moMicrodose semaglutide, 1-month plan, compounded
- Tirz
- $199/moMicrodose tirzepatide, 1-month plan, compounded
- Coverage
- Multi-state
- Brand
- Compounded
Compared with Lyfe Rx: $46.5/mo less for semaglutide · $128.18/mo less for tirzepatide · offers an oral option
Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.