1st Optimal review
1st Optimal is a Michigan-based hormone and metabolic telehealth practice founded by Dr. Amber Miller, a functional medicine physician, offering GLP-1 weight-loss care alongside broader hormone and lab-based programs.
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Compounded only
Pricing verified August 2026
The Index scorecard
1st Optimal scored on our six Cost-Efficiency Index factors. See the methodology.
Where the value is
- Named founder and clinical lead: Dr. Amber Miller, a functional medicine physician
- LegitScript verification badge displayed
- No credit card required to start the intake quiz
- Positions GLP-1 care within a broader labs-and-data-driven metabolic program
The tradeoffs
- No GLP-1 pricing published anywhere on the public site
- No compounding pharmacy partner named
- No published states-served list
- 'Members-only rates' language suggests price shopping requires committing to intake first
The bottom line
Best for: Patients who want a named founding physician and a broader functional-medicine/hormone workup alongside GLP-1s. 1st Optimal is a Michigan-based hormone and metabolic telehealth practice founded by Dr. Amber Miller, a functional medicine physician, offering GLP-1 weight-loss care alongside broader hormone and lab-based programs.
Ranked #518 of 539 providers on the Cost-Efficiency Index — see our #1 pick, CoreAge Rx, for comparison.
Compare with other providers
All 538 other providers we've modeled, in Cost-Efficiency Index order. See the ranked alternatives to 1st Optimal.
- #522Teladoc Health— Teladoc Health is the large, publicly traded telehealth company; its GLP-1 program is only accessible through an employer- or insurance-sponsored plan.41/100
- #523Thriving Again— Thriving Again is a men's health telehealth platform bundling TRT, peptides, hair restoration, and GLP-1 weight loss under one membership model, claiming coverage in all 50 states.41/100
- #524Ways2Well— Ways2Well is a concierge functional-medicine membership (founded by Brigham Buhler) built around biannual biomarker panels and personalized protocols that CAN include semaglutide/tirzepatide, peptides.41/100
- #525Cabana— Cabana is a concierge wellness brand offering compounded GLP-1 semaglutide and tirzepatide (injections and a semaglutide tablet) alongside NAD+ energy products, advertised from $249/month.40/100
- #526LevelUp Rx— LevelUp Rx is a broad multi-vertical telehealth pharmacy that lists GLP-1/weight-loss medications among several unrelated categories (hair loss, beauty, sexual health, longevity) but discloses zero actual pricing anywhere on its public site.40/100
- #527Wellspring Longevity Clinic— Wellspring Longevity Clinic is a longevity-focused telehealth service offering compounded GLP-1 (semaglutide) and dual GLP-1/GIP (tirzepatide) for weight management, plus NAD+, peptide therapy.40/100
The 18 programs nearest this one
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- #533 Immortals38
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- #536 RxSaludable38
- #537 California Trim Clinic37
- #538 Believe Health37
- #539 Thryve22
- #1 CoreAge Rx94
- #2 Found88
- #3 Ondra Health90
Pricing, states and verification reflect 1st Optimal's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on 1st Optimal's site. Not medical advice; see our disclosure.