Defy Medical Review: Price, Pros & Cons
Defy Medical is a Tampa-based men's-health and hormone-optimization (TRT) clinic led by Medical Director Dr. Justin Saya that also genuinely offers compounded semaglutide and tirzepatide as an add-on service.
In this review
Prices at a glance
- Semaglutide
- Not disclosed
- Tirzepatide
- Not disclosed
- Coverage
- Coverage not published
- Brand-name
- Not confirmed
Who Defy Medical may suit
Men already in TRT or hormone care who want to add a GLP-1 with the same clinic, rather than shoppers comparing GLP-1 prices alone.
Where the value is
- Named, credentialed Medical Director (Dr. Justin Saya)
- Large third-party review base (3,999 Trustpilot reviews, 5-star average)
- Offers both semaglutide and tirzepatide alongside broader men's-health services
- In-house pharmacy referenced by at least one patient testimonial
The tradeoffs
- GLP-1 is clearly a secondary offering bolted onto a primarily TRT/hormone-optimization practice, not its core focus
- Zero pricing disclosed on its site -- fully gated behind quiz/consultation
- No LegitScript certification
- No named compounding pharmacy or states-served list
A hormone clinic that also prescribes GLP-1s
Defy Medical is a Tampa, Florida, concierge clinic best known for testosterone and hormone therapy. It treats most patients by telemedicine, and weight loss is one of its service lines. Its providers can prescribe semaglutide, tirzepatide and liraglutide, and it also lists semaglutide as under-the-tongue oral drops. The lead physician and medical director is Dr. Justin Saya.
Defy doesn't publish a price for any GLP-1, for the consultation or for the lab work a weight plan needs. You see costs as you go: lab orders are bought separately, and medication is ordered and paid for in the patient portal after a provider prescribes it. Ask for the full monthly figure for your drug and dose, plus the consult and lab charges, before you commit.
Considering Defy Medical?
Check the plan total, billing period and cancellation terms before you enroll. A clinician decides whether treatment is appropriate.
How starting works
You fill in a Get Started form, and a patient advocate contacts you to explain the new-patient requirements, such as blood testing, a recent physical and your medical history. Defy treats bloodwork as the starting point for a weight plan, to look for conditions that make weight hard to lose. Labs are drawn at a LabCorp near you, and results usually take five to ten business days.
You then meet a provider by telemedicine, and Defy offers extended consults if you want more time. If a GLP-1 is appropriate, it can be part of a wider plan that may include other medications or supplements.
Who fills the prescription
Defy doesn't make or ship medication itself. When you order in the patient portal, its team checks the order against your care plan and sends it to a pharmacy in its vendor network. That pharmacy makes and ships the medication and sends you tracking. Defy doesn't name the pharmacies, so ask which one will fill yours and whether the drug is compounded or brand-name.
Money and insurance
Defy doesn't take any insurance and won't contact your insurer. Lab orders stay valid for three months and can be renewed once for free. A lab order can be refunded only before your sample is submitted. Within 90 days of purchase the refund goes to your card. From 91 to 180 days you get store credit instead, minus a $25 processing fee.
The Index scorecard
Defy Medical scored on our six Cost-Efficiency Index factors. See the methodology.
The bottom line
Defy Medical is a Tampa-based men's-health and hormone-optimization (TRT) clinic led by Medical Director Dr. Justin Saya that also genuinely offers compounded semaglutide and tirzepatide as an add-on service.
Compare the total cost of other GLP-1 programs and alternatives to Defy Medical before deciding. A clinician should help you choose the right treatment.
Other programs to compare with Defy Medical
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WillowPartner
Semaglutide modeled $299/mo · Tirzepatide modeled $399/mo
Willow is a direct-to-consumer telehealth provider offering compounded semaglutide and tirzepatide in both injectable and oral-tablet form at identical prices per format.
MEDGmPartner
Semaglutide modeled $299/mo · Tirzepatide modeled $399/mo
MEDGm charges $299 a month for compounded semaglutide injections and $399 for tirzepatide once the $120 welcome coupon lapses, prints every plan length on its product pages, and names the four pharmacies that fill its prescriptions.
Luvo HealthPartner
Semaglutide modeled $226.42/mo · Tirzepatide modeled $269.75/mo
Luvo charges $209 every four weeks for compounded semaglutide and $249 for tirzepatide, with half off the first delivery and brand-name Ozempic or Zepbound available.
Compare with other providers
The providers whose Cost-Efficiency Index scores sit closest to Defy Medical's. See the alternatives to Defy Medical.
- Rugiet— Rugiet sells ED, testosterone and men's health treatments plus Weigh In, an oral bupropion, naltrexone and metformin plan; it doesn't sell GLP-1 medication.43/100
- Grüns— Grüns sells greens supplement gummies by subscription from about $1.78 a day; it isn't a prescriber and doesn't sell GLP-1 medication.43/100
- Future— Future is remote one-on-one personal training at $50 for the first month, then $199 a month; it isn't a prescriber and doesn't sell GLP-1 medication.43/100
- HumeCare+— HumeCare is a telehealth weight-loss platform genuinely prescribing semaglutide or tirzepatide (chosen by a named physician) with muscle-preserving B-vitamin supplementation and a proprietary body-composition tracker.42/100
- Glam Health— Low advertised prices on both molecules plus NAD+, but few trust signals — no LegitScript, no named clinicians or pharmacy, and no state list.42/100
- TideMedix— TideMedix advertises a shared $99 first-month GLP-1 program floor. It offers semaglutide and tirzepatide assessment paths but does not publish separate standing monthly prices.42/100
Pricing, states and verification reflect Defy Medical's public disclosures at last review; the Cost-Efficiency Index is our editorial judgment per the methodology. Prices change — confirm on Defy Medical's site. Not medical advice; see our disclosure.