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Alternatives

Alternatives to TMates

TMates scores 68/100 on our Cost-Efficiency Index . Here are other programs to consider, each scored the same way. Partners are listed first.

Read the TMates review →CoreAge Rx vs TMates →

TMates at a glance

Semaglutide
$249/moMonth to month, same price at every dose, compounded
Tirzepatide
$297/moMonth to month, same price at every dose, compounded
Coverage
Not published ("most states")
Brand-name GLP-1s
Yes
Oral option
Yes
Pricing verified
October 2026

7 of the 8 programs below list semaglutide for less than TMates's $249 a month. 2 of the 8 list tirzepatide for less than its $297 a month.

TMates sells compounded semaglutide at $249 a month and tirzepatide at $297, the same at every dose, with lower rates down to $158 and $167 only if you prepay up to 12 months.

Best for: Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.

What TMates does well

  • Each product page lists every plan: semaglutide is $249 for one month, $650 for three, $1,050 for six and $1,900 for twelve; tirzepatide is $297, $800, $1,299 and $1,999
  • The price covers the medication, telemedicine visits and coaching, and stays the same at every dose
  • Semaglutide comes as a weekly injection or an oral option, and brand Wegovy or Zepbound can be prescribed for $99 a month to fill at your own pharmacy
  • No contract on the monthly plan; the product pages say you can cancel anytime

Why readers look for an alternative

  • The "from $158" and "from $167" category prices are 12-month prepaid rates; month to month is $249 and $297
  • No refund once your prescription is sent to the pharmacy
  • No state list: one page says it ships to "most states" and another says "50+ states"
  • The $99 brand-name plan covers only the visit and prescription; the Wegovy or Zepbound itself is bought separately at your pharmacy
  • The dispensing pharmacy isn't named
  • Compounded semaglutide and tirzepatide are not FDA-approved products
  1. Partner
    01A

    CoreAge Rx

    CoreAge Rx charges one flat price at every dose, $99 a month for semaglutide and $149 for tirzepatide, with no membership fee.

    Sema
    $99/mo
    Tirz
    $149/mo
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with TMates: $150/mo less for semaglutide · $148/mo less for tirzepatide · compounded only, no brand-name GLP-1s · no oral option

    Visit CoreAge Rx CoreAge Rx vs TMates →
  2. 02C

    SexyMD

    SexyMD prints "from $199" and "from $299" on every page, but those are its 48-week commitment rates: the four-week price is $269 for compounded semaglutide and $369 for tirzepatide.

    Sema
    $269/moOn the four-week plan (the site's "from $199" is the 48-week commitment rate)
    Tirz
    $369/moOn the four-week plan (the site's "from $299" is the 48-week commitment rate)
    Coverage
    47 states
    Brand
    Compounded

    Compared with TMates: $20/mo more for semaglutide · $72/mo more for tirzepatide · compounded only, no brand-name GLP-1s · no oral option

    Visit SexyMD SexyMD vs TMates →
  3. 03C

    Neuvé Health

    Neuvé Health prices twelve GLP-1 products openly — injectable and sublingual, standard and low dose, with a B12 or a glycine base — and then says three different things about whether the medication is inside the monthly figure.

    Sema
    $217/monthStandard injectable with B12; the site gives three different answers on whether the medication is inside the figure
    Tirz
    $324/monthStandard injectable with B12; same unresolved question about what the figure covers
    Coverage
    All 50 states
    Brand
    Compounded

    Compared with TMates: $32/mo less for semaglutide · $27/mo more for tirzepatide · compounded only, no brand-name GLP-1s

    Visit Neuvé Health Neuvé Health vs TMates →
  4. 04C

    Mixx Health & Wellness

    Mixx Health & Wellness is a compounded-GLP-1 telehealth clinic under medical director Dr. James David Lawrence III, MD (Georgia), sourcing 'Compounded GLP-1/GIP' from a named pharmacy, Promise Pharmacy (Palm Harbor, FL).

    Sema
    $120/moStarting dose, compounded
    Tirz
    Not disclosed
    Coverage
    44 states
    Brand
    Compounded

    Compared with TMates: $129/mo less for semaglutide · compounded only, no brand-name GLP-1s · no oral option

    Visit Mixx Health & Wellness Mixx Health & Wellness vs TMates →
  5. 05C

    Medical Health Institute

    Medical Health Institute is a multi-service telehealth provider (weight loss, testosterone therapy, peptide therapy) advertising GLP-1 weight loss 'starting at $100/mo' a figure the company itself footnotes as contingent.

    Sema
    $100/moAll doses, compounded
    Tirz
    Not disclosed
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with TMates: $149/mo less for semaglutide · compounded only, no brand-name GLP-1s · no oral option

    Visit Medical Health Institute Medical Health Institute vs TMates →
  6. 06C

    YOURx Health

    YOURx Health is a compounded GLP-1 telehealth platform operating under the MD Integrations physician network, selling semaglutide and tirzepatide as both weekly injections and daily oral RDT tablets, each enhanced with B12.

    Sema
    $169/moAll doses, promotional rate, bundle, compounded
    Tirz
    $189/moAll doses, promotional rate, compounded
    Coverage
    Multi-state
    Brand
    Compounded

    Compared with TMates: $80/mo less for semaglutide · $108/mo less for tirzepatide · compounded only, no brand-name GLP-1s

    Visit YOURx Health YOURx Health vs TMates →
  7. 07C

    Wholesome Clinic

    Wholesome Clinic is primarily an integrative psychiatry and wellness practice in Frisco, TX, led by NP Stephanie Ukoha.

    Sema
    $149/mo0.5 mg dose, compounded
    Tirz
    $349/mo5.0 mg dose, compounded
    Coverage
    7 states
    Brand
    Compounded

    Compared with TMates: $100/mo less for semaglutide · $52/mo more for tirzepatide · compounded only, no brand-name GLP-1s

    Visit Wholesome Clinic Wholesome Clinic vs TMates →
  8. 08C

    WeightWatchers Clinic

    WeightWatchers Clinic (Med+) is the telehealth medical arm of the long-established WeightWatchers brand, prescribing FDA-approved branded GLP-1s (Wegovy, Zepbound) and non-GLP-1 alternatives (Saxenda, Metformin) rather than compounded drugs.

    Sema
    $74/moBrand Wegovy, 12-month plan, plus a separate fee
    Tirz
    Not disclosed
    Coverage
    All 50 states
    Brand
    Yes

    Compared with TMates: $175/mo less for semaglutide · no oral option

    Visit WeightWatchers Clinic WeightWatchers Clinic vs TMates →

Assume any provider we list may compensate us — it never changes the Cost-Efficiency Index. Pricing and coverage reflect public disclosures at last review; confirm on each provider's site. Not medical advice. See our disclosure.

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