Head-to-head · Cost-Efficiency Index
Wholesome Clinic vs TMates
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Wholesome Clinic
Patients in TX/CO/NM/OK/LA/AR/OR who want GLP-1 weight loss bundled with psychiatric/whole-person care from one provider, and who value transparent dose-tiered pricing.
Visit Wholesome ClinicTMates
Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.
Visit TMatesThe verdict
Wholesome Clinic and TMates tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers, so choose on fit. Wholesome Clinic: Patients in TX/CO/NM/OK/LA/AR/OR who want GLP-1 weight loss bundled with psychiatric/whole-person care from one provider, and who value transparent dose-tiered pricing. TMates: Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Wholesome Clinic.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Wholesome Clinic | TMates |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $149/mo0.5 mg dose, compounded | $249/moMonth to month, same price at every dose, compounded |
| Tirzepatide / mo | $349/mo5.0 mg dose, compounded | $297/moMonth to month, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $1,788 | $2,988 |
| Tirzepatide / yr (modeled) | $4,188 | $3,564 |
| Coverage | 7 states | Not published ("most states") |
| Oral / sublingual | Yes | Yes |
| Brand-name access | Compounded only | Yes |
| Rank here | #154 | #160 |
Wholesome Clinic
68/100Where the value is
- Real, named, dual-certified prescriber (Stephanie Ukoha, DNP, FNP-BC, PMHNP-BC)
- Transparent dose-tiered pricing for both injectable and oral GLP-1 options, with no evident promo bait-and-switch
- Oral ODT alternatives offer a notably cheaper entry point ($109/mo semaglutide, $249/mo tirzepatide)
The tradeoffs
- Weight loss is a secondary service line to the clinic's core psychiatry focus, not its specialty
- Only licensed in seven states -- far narrower than most national GLP-1 telehealth competitors
TMates
68/100Where the value is
- Each product page lists every plan: semaglutide is $249 for one month, $650 for three, $1,050 for six and $1,900 for twelve; tirzepatide is $297, $800, $1,299 and $1,999
- The price covers the medication, telemedicine visits and coaching, and stays the same at every dose
- Semaglutide comes as a weekly injection or an oral option, and brand Wegovy or Zepbound can be prescribed for $99 a month to fill at your own pharmacy
The tradeoffs
- The "from $158" and "from $167" category prices are 12-month prepaid rates; month to month is $249 and $297
- No refund once your prescription is sent to the pharmacy
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.