Head-to-head · Cost-Efficiency Index
Mixx Health & Wellness vs TMates
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Mixx Health & Wellness
Shoppers who want a named medical director and a named compounding pharmacy, and who will ask for a tirzepatide quote since it isn't published.
Visit Mixx Health & WellnessTMates
Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.
Visit TMatesThe verdict
Mixx Health & Wellness and TMates tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers, so choose on fit. Mixx Health & Wellness: Shoppers who want a named medical director and a named compounding pharmacy, and who will ask for a tirzepatide quote since it isn't published. TMates: Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Mixx Health & Wellness.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Mixx Health & Wellness | TMates |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $120/moStarting dose, compounded | $249/moMonth to month, same price at every dose, compounded |
| Tirzepatide / mo | Not disclosed | $297/moMonth to month, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $1,440 | $2,988 |
| Tirzepatide / yr (modeled) | — | $3,564 |
| Coverage | 44 states | Not published ("most states") |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Yes |
| Rank here | #157 | #160 |
Mixx Health & Wellness
68/100Where the value is
- Names its medical director (Dr. James David Lawrence III, MD) and its compounding pharmacy (Promise Pharmacy, Palm Harbor, FL), which most programs we track don't
- Free ($0) consultation and 'Unlimited Check-ins' with no extra charge stated
- Licensed in a genuinely large footprint — 44 states per the site's own count
The tradeoffs
- The only published price, 'Plans starting at $120/mo,' is not broken out by drug — there is no separate tirzepatide/GIP price anywhere on the site even though tirzepatide is clearly offered through the same pharmacy
- A $125 cancellation/prescription-change fee applies if requested within 24 hours of payment, and all payments are stated to be final with non-refundable prescriptions
TMates
68/100Where the value is
- Each product page lists every plan: semaglutide is $249 for one month, $650 for three, $1,050 for six and $1,900 for twelve; tirzepatide is $297, $800, $1,299 and $1,999
- The price covers the medication, telemedicine visits and coaching, and stays the same at every dose
- Semaglutide comes as a weekly injection or an oral option, and brand Wegovy or Zepbound can be prescribed for $99 a month to fill at your own pharmacy
The tradeoffs
- The "from $158" and "from $167" category prices are 12-month prepaid rates; month to month is $249 and $297
- No refund once your prescription is sent to the pharmacy
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.