Head-to-head · Cost-Efficiency Index
Medical Health Institute vs TMates
Two GLP-1 programs on the bench, scored on the same six factors. Here's how their real cost of ownership compares — and which one we'd start with.
Medical Health Institute
Shoppers comparing across TRT, peptides, and weight loss under one provider who don't need public pricing detail up front.
Visit Medical Health InstituteTMates
Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.
Visit TMatesThe verdict
Medical Health Institute and TMates tie on the Cost-Efficiency Index at 68/100, so neither wins outright on the numbers, so choose on fit. Medical Health Institute: Shoppers comparing across TRT, peptides, and weight loss under one provider who don't need public pricing detail up front. TMates: Shoppers who want a flat price at every dose, with an oral semaglutide option and a provider who can also prescribe brand Wegovy or Zepbound.
Worth knowing either way: CoreAge Rx is one of our partners and leads our leaderboard, where partners are listed first (Cost-Efficiency Index 94/100). See how it stacks up: CoreAge Rx vs Medical Health Institute.
Factor by factor
Both providers scored on our six Cost-Efficiency Index factors. The stronger side on each row is marked in teal.
Normalized Cost/Month
Price Transparency
Nationwide Access
Formulation Options
Clinical Oversight
Contract Flexibility
Pricing, coverage & formulary
The disclosed facts behind the scores. Lower price wins its row (teal).
| Spec | Medical Health Institute | TMates |
|---|---|---|
| Cost-Efficiency Index | 68/100 | 68/100 |
| Semaglutide / mo | $100/moAll doses, compounded | $249/moMonth to month, same price at every dose, compounded |
| Tirzepatide / mo | Not disclosed | $297/moMonth to month, same price at every dose, compounded |
| Semaglutide / yr (modeled) | $1,200 | $2,988 |
| Tirzepatide / yr (modeled) | — | $3,564 |
| Coverage | Coverage not published | Not published ("most states") |
| Oral / sublingual | No | Yes |
| Brand-name access | Compounded only | Yes |
| Rank here | #156 | #160 |
Medical Health Institute
68/100Where the value is
- Advertises a competitively low $100/mo entry price for GLP-1 weight loss
- Offers multiple service lines (weight loss, TRT, peptide therapy) under one provider
- LegitScript and HIPAA-compliance badges both displayed on the homepage
The tradeoffs
- The $100/mo headline price carries the company's own asterisk — '*Based on pharmacy availability' — meaning it is explicitly not a guaranteed rate before intake
- No dose tier or even which drug (semaglutide vs. tirzepatide) the $100 figure applies to is disclosed anywhere public
TMates
68/100Where the value is
- Each product page lists every plan: semaglutide is $249 for one month, $650 for three, $1,050 for six and $1,900 for twelve; tirzepatide is $297, $800, $1,299 and $1,999
- The price covers the medication, telemedicine visits and coaching, and stays the same at every dose
- Semaglutide comes as a weekly injection or an oral option, and brand Wegovy or Zepbound can be prescribed for $99 a month to fill at your own pharmacy
The tradeoffs
- The "from $158" and "from $167" category prices are 12-month prepaid rates; month to month is $249 and $297
- No refund once your prescription is sent to the pharmacy
Assume any provider we list may compensate us — we may earn a commission, at no cost to you. It never changes the Cost-Efficiency Index. Pricing, states and verification reflect each provider's public disclosures at last review; prices change — confirm on the provider's site. Not medical advice. See our disclosure.